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Preface
Acknowledgments
Part I. The opioid epidemic: 1. Chronic pain and opioids; 2. Current costs of the opioid epidemic; 3. Opioid use disorder
Part II. Overview of cannabis: 4. History and legality of cannabis; 5. Overview of the endocannabinoid system
Part III. Cannabinoids: 6. Cannabinoids and terpenes; 7. Synthetic cannabinoid pharmaceuticals; 8. Isolate cannabinoid pharmaceuticals
Part IV. Medical marijuana: 9. Medical marijuana and bioavailability; 10. Side effects of cannabis use
Part V. Chronic pain management: 11. Causes of chronic pain; 12. Treating chronic pain with opioids; 13. Treating chronic pain with cannabinoids
Part VI. Cannabinoids and the opioid crisis: 14. Cannabinoid and opioid interactions; 15. Cannabis as an adjunct to opioids; 16. Opioid sparing with cannabinoids
Appendix A. Centers for Disease Control and Prevention guideline for prescribing opioids for chronic pain
Appendix B. National Institutes of Drug Abuse quick screen and NIDA-Modified ASSIST screenings for opioid use disorder
Appendix C. Centers for Disease Control and Prevention calculating total daily dose of opioids for safer dosage.

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