U.S. 2 : St. Ignace, Michigan, to Ironwood, Michigan
U.S. 12 : Ypsilanti, Michigan, to Beverly Shores, Indiana
U.S. 20 : Oberlin, Ohio, to South Bend, Indiana
U.S. 22 : Steubenville, Ohio, to Cincinnati, Ohio
U.S. 23 and Michigan 25 : Mackinaw City, Michigan, to Port Huron, Michigan
U.S. 24 : Monroe, Michigan, to Kentland, Indiana
U.S. 27 : Angola, Indiana, to Cincinnati, Ohio
U.S. 31 : Carp Lake, Michigan, to Ludington, Michigan
U.S. 35 : Michigan City, Indiana, to Gallipolis, Ohio
U.S. 36 : Uhrichsville, Ohio, to Dana, Indiana
U.S. 41 : Copper Harbor, Michigan, to Menominee, Michigan
U.S. 50 : Belpre, Ohio, to Vincennes, Indiana
U.S. 52 : Burlington, Ohio, to Finly, Indiana
U.S. 62 : Youngstown, Ohio, to Aberdeen, Ohio
U.S. 231 : Crown Point, Indiana, to Rockport, Indiana
U.S. 250 : Sandusky, Ohio, to Bridgeport, Ohio
U.S. 421 : Michigan City, Indiana, to Madison, Indiana
Indiana 135 : Indianapolis, Indiana, to Corydon, Indiana
Ohio 7 : Martins Ferry, Ohio, to Chesapeake, Ohio.