@article{1387405, note = {"Bradford book."}, author = {Kohane, Isaac S. and Kho, Alvin T. and Butte, Atul J.}, url = {http://library.usi.edu/record/1387405}, title = {Microarrays for an integrative genomics /}, publisher = {MIT Press,}, abstract = {Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level.This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.}, recid = {1387405}, pages = {1 online resource (xviii, 306 pages) :}, address = {Cambridge, Mass :}, year = {2003}, }