TY - GEN N2 - Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level.This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics. AB - Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level.This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics. T1 - Microarrays for an integrative genomics / DA - ©2003. CY - Cambridge, Mass : AU - Kohane, Isaac S. AU - Kho, Alvin T. AU - Butte, Atul J. CN - QP624.5.D726 PB - MIT Press, PP - Cambridge, Mass : PY - ©2003. N1 - "Bradford book." ID - 1387405 KW - DNA microarrays. KW - Genomics KW - Bioinformatics. KW - BIOMEDICAL SCIENCES/Quantitative Biology SN - 9780262277372 SN - 0262277379 SN - 0585477647 SN - 9780585477640 TI - Microarrays for an integrative genomics / LK - https://univsouthin.idm.oclc.org/login?url=https://doi.org/10.7551/mitpress/4594.001.0001?locatt=mode:legacy LK - http://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf UR - https://univsouthin.idm.oclc.org/login?url=https://doi.org/10.7551/mitpress/4594.001.0001?locatt=mode:legacy UR - http://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf ER -