001387446 000__ 02850cam\a2200493Ia\4500 001387446 001__ 1387446 001387446 003__ MaCbMITP 001387446 005__ 20240325105114.0 001387446 006__ m\\\\\o\\d\\\\\\\\ 001387446 007__ cr\cn\nnnunnun 001387446 008__ 030402s2002\\\\maua\\\\ob\\\\001\0\eng\d 001387446 020__ $$a9780262283984$$q(electronic bk.) 001387446 020__ $$a0262283980$$q(electronic bk.) 001387446 020__ $$a0585442592$$q(electronic bk.) 001387446 020__ $$a9780585442594$$q(electronic bk.) 001387446 020__ $$z0262194732$$q(hbk.) 001387446 020__ $$z9780262194730$$q(hbk.) 001387446 035__ $$a(OCoLC)51958073$$z(OCoLC)60573083$$z(OCoLC)733807832$$z(OCoLC)990742292$$z(OCoLC)991905539$$z(OCoLC)1020520002 001387446 035__ $$a(OCoLC-P)51958073 001387446 040__ $$aOCoLC-P$$beng$$epn$$cOCoLC-P 001387446 050_4 $$aQP363.3$$b.S525 2002eb 001387446 072_7 $$aSOC$$x002020$$2bisacsh 001387446 08204 $$a573.8/36$$221 001387446 1001_ $$aSmythies, John R.$$q(John Raymond),$$d1922- 001387446 24514 $$aThe dynamic neuron :$$ba comprehensive survey of the neurochemical basis of synaptic plasticity /$$cJohn Smythies. 001387446 260__ $$aCambridge, Mass. :$$bMIT Press,$$c©2002. 001387446 264_4 $$c©2002 001387446 300__ $$a1 online resource (viii, 150 pages) :$$billustrations 001387446 336__ $$atext$$btxt$$2rdacontent 001387446 337__ $$acomputer$$bc$$2rdamedia 001387446 338__ $$aonline resource$$bcr$$2rdacarrier 001387446 500__ $$a"A Bradford book." 001387446 506__ $$aAccess limited to authorized users. 001387446 5208_ $$aThe traditional model of synapses as fixed structures has been replaced by a dynamic one in which synapses are constantly being deleted and replaced. This book, written by a leading researcher on the neurochemistry of schizophrenia, integrates material from neuroscience and cell biology to provide a comprehensive account of our current knowledge of the neurochemical basis of synaptic plasticity. The book presents the evidence for synaptic plasticity, an account of the dendritic spine and the glutamate synapse with a focus on redox mechanisms, and the biochemical basis of the Hebbian synapse. It discusses the role of endocytosis, special proteins, and local protein synthesis. Additional topics include volume transmission, arachidonic acid signaling, hormonal modulation, and psychological stress. Finally, the book considers pharmacological and clinical implications of current research, particularly with reference to schizophrenia and Alzheimer's disease. 001387446 588__ $$aOCLC-licensed vendor bibliographic record. 001387446 650_0 $$aNeuroplasticity. 001387446 650_0 $$aNeurochemistry. 001387446 655_0 $$aElectronic books 001387446 852__ $$bebk 001387446 85640 $$3MIT Press$$uhttps://univsouthin.idm.oclc.org/login?url=https://doi.org/10.7551/mitpress/2518.001.0001?locatt=mode:legacy$$zOnline Access through The MIT Press Direct 001387446 85642 $$3OCLC metadata license agreement$$uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf 001387446 909CO $$ooai:library.usi.edu:1387446$$pGLOBAL_SET 001387446 980__ $$aBIB 001387446 980__ $$aEBOOK 001387446 982__ $$aEbook 001387446 983__ $$aOnline