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Intro
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Contents
Chapter 1 Introduction
1.1 Background
1.2 Noble Metals
1.3 Ferromagnetic Metals
1.4 Quantum Dots
1.5 Carbon Materials
1.6 Layered Double Hydroxides
1.7 Transition Metal Dichalcogenides
1.8 Silica-based Biomaterials
1.9 Metal-Organic Frameworks
1.10 Scope
References
Chapter 2 Inorganic Materials in Drug Delivery
2.1 Introduction
2.2 Metal-Organic Frameworks
2.2.1 Introduction
2.2.2 General Synthesis Methods
2.2.3 Typical Properties
2.2.4 Biocompatibility
2.2.5 In Vivo Toxicity

2.2.6 Drug Loading and Delivery
2.2.7 Stimuli-responsive Drug Delivery
2.2.8 Combination with Other Materials and Techniques
2.2.9 Summary and Outlook
2.3 Mesoporous Silica Nanoparticles
2.3.1 Introduction
2.3.2 Synthesis of MSNs
2.3.3 MSN Characteristics Influencing Drug Delivery
2.3.4 MSN-based Drug Delivery
2.3.5 Multifunctional MSNs
2.3.6 Summary and Outlook
2.4 Layered Materials
2.4.1 Introduction
2.4.2 Properties of Layered Materials
2.4.3 Types of Layered Materials
2.4.4 General Synthesis
2.4.5 Cytotoxicity
2.4.6 Drug Delivery

2.4.7 Summary and Outlook
2.5 Metallic Nanoparticles
2.5.1 Introduction
2.5.2 Synthesis and Properties
2.5.3 Cytotoxicity and Biocompatibility
2.5.4 Drug Delivery and Targeting
2.5.5 Combining Drug Delivery with Other Techniques
2.5.6 Hybrid Nanoparticles
2.5.7 Summary and Outlook
2.6 Conclusion
References
Chapter 3 Imaging Applications of Inorganic Nanomaterials
3.1 Introduction
3.2 Classes of Inorganic Nanomaterials for Diagnostic Imaging
3.2.1 Magnetic Nanomaterials
3.2.2 Optical Nanomaterials
3.2.3 Acoustic Nanomaterials

3.2.4 Nuclear Nanomaterials
3.2.5 Carrier Nanomaterials
3.3 Inorganic Materials in Diagnostic Imaging Modalities
3.3.1 MRI Contrast Agents
3.3.2 Nuclear Imaging Nanoprobes
3.3.3 Optical Imaging Nanoprobes
3.3.4 X-ray Computed Tomography Nanoprobes
3.3.5 Ultrasound Nanoprobes
3.3.6 PAI and PAT Nanoprobes
3.3.7 Comparison of Imaging Techniques and Advantages of Multimodality
3.4 Applications in Bioimaging
3.4.1 Single Modality Agents
3.4.2 Agents for Dual and Higher-modality Imaging
3.4.3 Agents for Higher-modality Imaging

3.5 In Vivo Biodistribution, Excretion, and Toxicity of Nanomaterials
3.6 Examples of Clinical Trials
3.7 Conclusions and Perspectives
References
Chapter 4 Diagnostic and Theranostic Applications of Inorganic Materials
4.1 Introduction
4.2 Inorganic Nanomaterials in the Biomedical Field
4.2.1 Iron Oxide-based Nanomaterials
4.2.2 Gold-based Nanomaterials
4.2.3 Silica-based Nanomaterials
4.2.4 Carbon-based Nanomaterials
4.2.5 Other Inorganic Nanomaterials
4.3 Inorganic Nanomaterials for Biomarker Detection
4.3.1 Introduction to Biomarkers

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