Introduction to systems biology in drug discovery and development
Methods for in silico biology : model construction and analysis
Methods in in silico biology : modeling feedback dynamics in pathways
Simulation of population variability in pharmacokinetics
Applications of systems biology approaches to target identification and validation in drug discovery
Lead identification and optimization
The role of core biological motifs in dose-response modeling : an example with switch-like circuits
Mechanism based pharmacokinetic-pharmacodynamic modeling during discovery and early development
Developing oncology drugs using virtual patients of vascular tumor diseases
Systems modeling applied to candidate biomarker identification
Simulating clinical trials
Pathway analysis in drug discovery
Functional mapping for predicting drug response and enabling personalized medicine
Future outlook of systems biology.