001412382 000__ 04222cam\a2200709Ki\4500 001412382 001__ 1412382 001412382 003__ MaCbMITP 001412382 005__ 20240325105222.0 001412382 006__ m\\\\\o\\d\\\\\\\\ 001412382 007__ cr\cn\nnnunnun 001412382 008__ 131118s2014\\\\maua\\\\ob\\\\001\0\eng\d 001412382 020__ $$a9781461952183$$q(electronic bk.) 001412382 020__ $$a1461952182$$q(electronic bk.) 001412382 020__ $$a9780262318389$$q(electronic bk.) 001412382 020__ $$a0262318385$$q(electronic bk.) 001412382 020__ $$a9780262318396$$q(electronic bk.) 001412382 020__ $$a0262318393$$q(electronic bk.) 001412382 020__ $$a1306140668 001412382 020__ $$a9781306140669 001412382 020__ $$z9780262019774 001412382 020__ $$z0262019779 001412382 0248_ $$aebr10803227 001412382 035__ $$a(OCoLC)863157576$$z(OCoLC)863672875$$z(OCoLC)864822098$$z(OCoLC)971582128$$z(OCoLC)971909028$$z(OCoLC)1055385038$$z(OCoLC)1066662229$$z(OCoLC)1081287918 001412382 035__ $$a(OCoLC-P)863157576 001412382 040__ $$aOCoLC-P$$beng$$erda$$epn$$cOCoLC-P 001412382 050_4 $$aR856$$bL383 2014eb 001412382 072_7 $$aHEA$$x012000$$2bisacsh 001412382 072_7 $$aHEA$$x020000$$2bisacsh 001412382 072_7 $$aMED$$x004000$$2bisacsh 001412382 072_7 $$aMED$$x101000$$2bisacsh 001412382 072_7 $$aMED$$x109000$$2bisacsh 001412382 072_7 $$aMED$$x029000$$2bisacsh 001412382 072_7 $$aMED$$x040000$$2bisacsh 001412382 072_7 $$aMED$$x092000$$2bisacsh 001412382 08204 $$a610.28$$223 001412382 1001_ $$aLee, W. David,$$d1946-$$eauthor. 001412382 24510 $$aFrom X-rays to DNA :$$bhow engineering drives biology /$$cDavid W. Lee, with Jeffrey Drazen, Phillip A. Sharp, and Robert S. Langer. 001412382 264_1 $$aCambridge, Massachusetts :$$bThe MIT Press,$$c[2014] 001412382 264_4 $$c©2014 001412382 300__ $$a1 online resource (xii, 233 pages) :$$billustrations 001412382 336__ $$atext$$btxt$$2rdacontent 001412382 337__ $$acomputer$$bc$$2rdamedia 001412382 338__ $$aonline resource$$bcr$$2rdacarrier 001412382 506__ $$aAccess limited to authorized users. 001412382 5203_ $$a"Engineering has been an essential collaborator in biological research and breakthroughs in biology are often enabled by technological advances. Decoding the double helix structure of DNA, for example, only became possible after significant advances in such technologies as X-ray diffraction and gel electrophoresis. Diagnosis and treatment of tuberculosis improved as new technologies -- including the stethoscope, the microscope, and the X-ray -- developed. These engineering breakthroughs take place away from the biology lab, and many years may elapse before the technology becomes available to biologists. In this book, David Lee argues for concurrent engineering -- the convergence of engineering and biological research -- as a means to accelerate the pace of biological discovery and its application to diagnosis and treatment. He presents extensive case studies and introduces a metric to measure the time between technological development and biological discovery. Investigating a series of major biological discoveries that range from pasteurization to electron microscopy, Lee finds that it took an average of forty years for the necessary technology to become available for laboratory use. Lee calls for new approaches to research and funding to encourage a tighter, more collaborative coupling of engineering and biology. Only then, he argues, will we see the rapid advances in the life sciences that are critically needed for life-saving diagnosis and treatment." 001412382 588__ $$aOCLC-licensed vendor bibliographic record. 001412382 650_0 $$aBiomedical engineering. 001412382 650_0 $$aMedicine$$xResearch$$xHistory. 001412382 650_0 $$aMedical instruments and apparatus$$xTechnological innovations. 001412382 650_0 $$aSurgical instruments and apparatus$$xTechnological innovations. 001412382 653__ $$aBIOMEDICAL SCIENCES/General 001412382 653__ $$aINFORMATION SCIENCE/Technology & Policy 001412382 655_0 $$aElectronic books 001412382 7001_ $$aDrazen, Jeffrey M.,$$d1946-$$eauthor. 001412382 7001_ $$aSharp, Phillip A.,$$eauthor. 001412382 7001_ $$aLanger, Robert S.,$$eauthor. 001412382 852__ $$bebk 001412382 85640 $$3MIT Press$$uhttps://univsouthin.idm.oclc.org/login?url=https://doi.org/10.7551/mitpress/8893.001.0001?locatt=mode:legacy$$zOnline Access through The MIT Press Direct 001412382 85642 $$3OCLC metadata license agreement$$uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf 001412382 909CO $$ooai:library.usi.edu:1412382$$pGLOBAL_SET 001412382 980__ $$aBIB 001412382 980__ $$aEBOOK 001412382 982__ $$aEbook 001412382 983__ $$aOnline