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Table of Contents
Intro
Half Title
Title
Copyright
Dedication
In Memoriam
Contributors
Preface
Foreword
Acknowledgments
Updates
About Our Process
November 2020
February 2021
May 2021
September 2021
January 2022
Contents
SECTION I Principles of Primary Care
Chapter 1 The Purpose and Practice of Primary Care
Chapter 2 Selection and Interpretation of Diagnostic Tests
Chapter 3 Health Maintenance and the Role of Screening
Chapter 4 Estimating and Communicating Risk and Prognosis
Chapter 5 Choosing among Treatment Options
Chapter 6 Immunization
Appendix 6-1: Vaccination for Travel
SECTION II Systemic Problems
Chapter 7 Screening for HIV Infection
Chapter 8 Evaluation of Chronic Fatigue
Chapter 9 Evaluation of Weight Loss
Chapter 10 Evaluation of Overweight and Obesity
Chapter 11 Evaluation of Fever
Chapter 12 Evaluation of Lymphadenopathy
Chapter 13 Approach to the Patient with Human Immunodeficiency Virus (HIV) Infection
Chapter 14 Screening for Hypertension
Chapter 15 Screening for Hyperlipidemia and Associated Coronary Heart Disease Risk Factors
Chapter 16 Infective Endocarditis Prophylaxis
Chapter 17 Prevention of Rheumatic Fever and Rheumatic Heart Disease
SECTION III Cardiovascular Problems
Chapter 18 Primary Prevention of Coronary Heart Disease
Appendix 18-1: Medical Screening of Potential Exercisers
Appendix 18-2: The Exercise Prescription
Chapter 19 Evaluation of Hypertension
Chapter 20 Evaluation of Chest Pain
Chapter 21 Evaluation of the Asymptomatic Systolic Murmur
Chapter 22 Evaluation of Leg Edema
Appendix 22-1: Screening for Occult Malignancy in Persons with Unprovoked Deep Vein Thrombosis
Appendix 22-2: Evaluation for Upper Extremity DVT
Chapter 23 Evaluation of Arterial Insufficiency of the Lower Extremities.
Chapter 24 Evaluation of Syncope
Chapter 25 Evaluation of Palpitations
Appendix 25-1: Evaluation of Atrial Fibrillation in the Outpatient Setting
Chapter 26 Management of Hypertension
Chapter 27 Approach to the Patient with a Lipid Disorder
Chapter 28 Outpatient Management of Atrial Fibrillation
Chapter 29 Management of Ventricular Irritability in the Ambulatory Setting
Chapter 30 Management of Chronic Stable Angina
Chapter 31 Secondary Prevention of Coronary Heart Disease after a Recent Acute Coronary Syndrome
Chapter 32 Approach to the Patient with Chronic Congestive Heart Failure
Appendix 32-1: Managing Disorders of Serum Potassium in Congestive Heart Failure
Chapter 33 Management of Valvular Heart Disease
Appendix 33-1: Approach to Hypertrophic Cardiomyopathy and Patent Foramen Ovale
Chapter 34 Management of Peripheral Artery Disease (PAD)
Chapter 35 Management of Peripheral Venous Disease
Chapter 36 Noninvasive Studies for Coronary Heart Disease
Appendix 36-1: Perioperative Medical Evaluation
SECTION IV Respiratory Problems
Chapter 37 Screening for Lung Cancer
Chapter 38 Tuberculosis Screening and Prophylaxis
Chapter 39 Evaluation and Prevention of Occupational and Environmental Lung Disease
Chapter 40 Evaluation of Chronic Dyspnea
Chapter 41 Evaluation of Subacute and Chronic Cough
Chapter 42 Evaluation of Hemoptysis
Chapter 43 Evaluation of Pleural Effusions
Chapter 44 Evaluation of the Solitary Pulmonary Nodule
Appendix 44-1: Evaluation of Multiple Incidental Pulmonary Nodules
Chapter 45 Evaluation of Clubbing
Chapter 46 Approach to the Patient with Obstructive Sleep Apnea
Chapter 47 Management of Chronic Obstructive Pulmonary Disease
Chapter 48 Management of Asthma
Chapter 49 Approach to the Patient with Tuberculosis.
Appendix 49-1: Approach to the Patient With Nontuberculous Mycobacterial Lung Disease
Chapter 50 Approach to Acute Uncomplicated Respiratory Tract Infection
Chapter 51 Management of Sarcoidosis
Appendix 51-1: Evaluation of Interstitial Lung Disease
Chapter 52 Outpatient Approach to Acute Lower Respiratory Tract Infection- Acute Bronchitis and Pneumonia
Appendix 52-1: SARS-COV-2 Infection
Chapter 53 Approach to the Patient with Lung Cancer
Chapter 54 Smoking Cessation
Appendix 54-1: Pulmonary Consequences of Other Forms of Smoking
SECTION V Gastrointestinal Problems
Chapter 55 Screening and Case Finding for Gastrointestinal Cancers
Chapter 56 Screening for Colorectal Cancer
Appendix 56-1: Examination of the Anorectum and Sigmoid Colon with Digital Rectal Examination, Anoscopy, and Sigmoidoscopy
Chapter 57 Screening for and Prevention of Viral Hepatitis
Chapter 58 Evaluation of Abdominal Pain
Appendix 58-1: Management of the Abdominal Aortic Aneurysm
Chapter 59 Evaluation of Nausea and Vomiting
Chapter 60 Evaluation of Dysphagia and Suspected Esophageal Chest Pain
Chapter 61 Approach to the Patient with Heartburn and Reflux (Gastroesophageal Reflux Disease)
Chapter 62 Evaluation of Jaundice
Appendix 62-1: Evaluation of the Asymptomatic Patient with an Incidental Elevation in a Liver Function Test
Chapter 63 Evaluation of Gastrointestinal Bleeding
Chapter 64 Evaluation and Management of Diarrhea
Chapter 65 Approach to the Patient with Constipation
Chapter 66 Approach to the Patient with Anorectal Complaints
Chapter 67 Approach to the Patient with an External Hernia
Chapter 68 Management of Peptic Ulcer Disease
Chapter 69 Management of Asymptomatic and Symptomatic Gallstones
Chapter 70 Management of Hepatitis.
Appendix 70-1: Recommended Direct-Acting Antiviral (DAA) Programs for Hepatitis C Virus Infection
Chapter 71 Management of Cirrhosis and Chronic Liver Failure
Chapter 72 Management of Pancreatitis
Chapter 73 Management of Inflammatory Bowel Disease
Chapter 74 Approach to the Patient with Functional Gastrointestinal Disease
Chapter 75 Management of Diverticular Disease
Chapter 76 Management of Gastrointestinal Cancers
SECTION VI Hematologic and Oncologic Problems
Chapter 77 Screening for Anemia
Chapter 78 Screening for Sickle Cell Disease and Sickle Cell Trait
Chapter 79 Evaluation of Anemia
Chapter 80 Evaluation of Erythrocytosis (Polycythemia)
Appendix 80-1: Other Myeloproliferative Disorders-Primary Myelofibrosis
Chapter 81 Evaluation of Bleeding Problems and Abnormal Bleeding Studies
Chapter 82 Management of Common Anemias
Appendix 82-1: Management of Asplenia
Chapter 83 Outpatient Oral Anticoagulant Therapy
Chapter 84 Approach to the Patient with Lymphoma
Chapter 85 Approach to the Patient with Metastatic Cancer of Unknown Primary Origin
Chapter 86 Approach to Staging and Monitoring
Chapter 87 Comprehensive Care of the Cancer Patient
Appendix 87-1: Cancer Prevention
Chapter 88 Principles of Cancer Drug Therapy
Chapter 89 Principles of Radiation Therapy
Chapter 90 Assessment and Relief of Chronic Cancer Pain and Palliative Care
Chapter 91 Managing the Gastrointestinal Complications of Cancer and Cancer Treatment
Chapter 92 Complications of Cancer: Oncologic Emergencies, Malignant Effusions, and Paraneoplastic Syndromes
SECTION VII Endocrinologic Problems
Chapter 93 Screening for Type 2 Diabetes Mellitus
Appendix 93-1: Screening for Gestational and Type 1 Diabetes
Chapter 94 Screening for Thyroid Cancer
Chapter 95 Evaluation of Thyroid Nodules.
Chapter 96 Approach to the Patient with Hypercalcemia
Chapter 97 Evaluation of Hypoglycemia
Chapter 98 Evaluation of Hirsutism
Appendix 98-1: Approach to an Incidentally Encountered Adrenal Mass
Chapter 99 Evaluation of Gynecomastia
Chapter 100 Evaluation of Galactorrhea and Hyperprolactinemia
Chapter 101 Evaluation of Suspected Diabetes Insipidus
Chapter 102 Approach to the Patient with Diabetes Mellitus
Chapter 103 Approach to the Patient with Hyperthyroidism
Chapter 104 Approach to the Patient with Hypothyroidism
Chapter 105 Glucocorticoid Therapy
SECTION VIII Gynecologic Problems
Chapter 106 Screening for Breast Cancer
Chapter 107 Screening for Cervical Cancer
Chapter 108 Screening for Ovarian Cancer
Chapter 109 Screening for Endometrial Cancer
Chapter 110 Screening for and Prevention of Intimate Partner Violence
Appendix 110-1: Screening for Firearm Risk
Chapter 111 Approach to the Woman with Abnormal Vaginal Bleeding
Chapter 112 Evaluation and Symptomatic Management of Secondary Amenorrhea
Chapter 113 Evaluation of Breast Masses and Nipple Discharges
Chapter 114 Evaluation of Vulvar Pruritus
Chapter 115 Medical Evaluation of Female Sexual Dysfunction
Chapter 116 Approach to the Patient with Pelvic Pain
Appendix 116-1: Premenstrual Syndrome/Premenstrual Dysphoric Disorder
Chapter 117 Approach to the Patient with an Abnormal Vaginal Discharge
Chapter 118 Approach to the Menopausal Woman
Appendix 118-1: Evaluation of Flushing
Chapter 119 Approach to Fertility Control
Chapter 120 Approach to the Infertile Couple
Chapter 121 Approach to the Woman with an Unplanned Pregnancy
Chapter 122 Management of Breast Cancer
Chapter 123 Management of the Woman with Genital Tract Cancer
SECTION IX Genitourinary Problems
Chapter 124 Screening for Syphilis.
Chapter 125 Screening for Chlamydia and Gonorrhea Infection.
Half Title
Title
Copyright
Dedication
In Memoriam
Contributors
Preface
Foreword
Acknowledgments
Updates
About Our Process
November 2020
February 2021
May 2021
September 2021
January 2022
Contents
SECTION I Principles of Primary Care
Chapter 1 The Purpose and Practice of Primary Care
Chapter 2 Selection and Interpretation of Diagnostic Tests
Chapter 3 Health Maintenance and the Role of Screening
Chapter 4 Estimating and Communicating Risk and Prognosis
Chapter 5 Choosing among Treatment Options
Chapter 6 Immunization
Appendix 6-1: Vaccination for Travel
SECTION II Systemic Problems
Chapter 7 Screening for HIV Infection
Chapter 8 Evaluation of Chronic Fatigue
Chapter 9 Evaluation of Weight Loss
Chapter 10 Evaluation of Overweight and Obesity
Chapter 11 Evaluation of Fever
Chapter 12 Evaluation of Lymphadenopathy
Chapter 13 Approach to the Patient with Human Immunodeficiency Virus (HIV) Infection
Chapter 14 Screening for Hypertension
Chapter 15 Screening for Hyperlipidemia and Associated Coronary Heart Disease Risk Factors
Chapter 16 Infective Endocarditis Prophylaxis
Chapter 17 Prevention of Rheumatic Fever and Rheumatic Heart Disease
SECTION III Cardiovascular Problems
Chapter 18 Primary Prevention of Coronary Heart Disease
Appendix 18-1: Medical Screening of Potential Exercisers
Appendix 18-2: The Exercise Prescription
Chapter 19 Evaluation of Hypertension
Chapter 20 Evaluation of Chest Pain
Chapter 21 Evaluation of the Asymptomatic Systolic Murmur
Chapter 22 Evaluation of Leg Edema
Appendix 22-1: Screening for Occult Malignancy in Persons with Unprovoked Deep Vein Thrombosis
Appendix 22-2: Evaluation for Upper Extremity DVT
Chapter 23 Evaluation of Arterial Insufficiency of the Lower Extremities.
Chapter 24 Evaluation of Syncope
Chapter 25 Evaluation of Palpitations
Appendix 25-1: Evaluation of Atrial Fibrillation in the Outpatient Setting
Chapter 26 Management of Hypertension
Chapter 27 Approach to the Patient with a Lipid Disorder
Chapter 28 Outpatient Management of Atrial Fibrillation
Chapter 29 Management of Ventricular Irritability in the Ambulatory Setting
Chapter 30 Management of Chronic Stable Angina
Chapter 31 Secondary Prevention of Coronary Heart Disease after a Recent Acute Coronary Syndrome
Chapter 32 Approach to the Patient with Chronic Congestive Heart Failure
Appendix 32-1: Managing Disorders of Serum Potassium in Congestive Heart Failure
Chapter 33 Management of Valvular Heart Disease
Appendix 33-1: Approach to Hypertrophic Cardiomyopathy and Patent Foramen Ovale
Chapter 34 Management of Peripheral Artery Disease (PAD)
Chapter 35 Management of Peripheral Venous Disease
Chapter 36 Noninvasive Studies for Coronary Heart Disease
Appendix 36-1: Perioperative Medical Evaluation
SECTION IV Respiratory Problems
Chapter 37 Screening for Lung Cancer
Chapter 38 Tuberculosis Screening and Prophylaxis
Chapter 39 Evaluation and Prevention of Occupational and Environmental Lung Disease
Chapter 40 Evaluation of Chronic Dyspnea
Chapter 41 Evaluation of Subacute and Chronic Cough
Chapter 42 Evaluation of Hemoptysis
Chapter 43 Evaluation of Pleural Effusions
Chapter 44 Evaluation of the Solitary Pulmonary Nodule
Appendix 44-1: Evaluation of Multiple Incidental Pulmonary Nodules
Chapter 45 Evaluation of Clubbing
Chapter 46 Approach to the Patient with Obstructive Sleep Apnea
Chapter 47 Management of Chronic Obstructive Pulmonary Disease
Chapter 48 Management of Asthma
Chapter 49 Approach to the Patient with Tuberculosis.
Appendix 49-1: Approach to the Patient With Nontuberculous Mycobacterial Lung Disease
Chapter 50 Approach to Acute Uncomplicated Respiratory Tract Infection
Chapter 51 Management of Sarcoidosis
Appendix 51-1: Evaluation of Interstitial Lung Disease
Chapter 52 Outpatient Approach to Acute Lower Respiratory Tract Infection- Acute Bronchitis and Pneumonia
Appendix 52-1: SARS-COV-2 Infection
Chapter 53 Approach to the Patient with Lung Cancer
Chapter 54 Smoking Cessation
Appendix 54-1: Pulmonary Consequences of Other Forms of Smoking
SECTION V Gastrointestinal Problems
Chapter 55 Screening and Case Finding for Gastrointestinal Cancers
Chapter 56 Screening for Colorectal Cancer
Appendix 56-1: Examination of the Anorectum and Sigmoid Colon with Digital Rectal Examination, Anoscopy, and Sigmoidoscopy
Chapter 57 Screening for and Prevention of Viral Hepatitis
Chapter 58 Evaluation of Abdominal Pain
Appendix 58-1: Management of the Abdominal Aortic Aneurysm
Chapter 59 Evaluation of Nausea and Vomiting
Chapter 60 Evaluation of Dysphagia and Suspected Esophageal Chest Pain
Chapter 61 Approach to the Patient with Heartburn and Reflux (Gastroesophageal Reflux Disease)
Chapter 62 Evaluation of Jaundice
Appendix 62-1: Evaluation of the Asymptomatic Patient with an Incidental Elevation in a Liver Function Test
Chapter 63 Evaluation of Gastrointestinal Bleeding
Chapter 64 Evaluation and Management of Diarrhea
Chapter 65 Approach to the Patient with Constipation
Chapter 66 Approach to the Patient with Anorectal Complaints
Chapter 67 Approach to the Patient with an External Hernia
Chapter 68 Management of Peptic Ulcer Disease
Chapter 69 Management of Asymptomatic and Symptomatic Gallstones
Chapter 70 Management of Hepatitis.
Appendix 70-1: Recommended Direct-Acting Antiviral (DAA) Programs for Hepatitis C Virus Infection
Chapter 71 Management of Cirrhosis and Chronic Liver Failure
Chapter 72 Management of Pancreatitis
Chapter 73 Management of Inflammatory Bowel Disease
Chapter 74 Approach to the Patient with Functional Gastrointestinal Disease
Chapter 75 Management of Diverticular Disease
Chapter 76 Management of Gastrointestinal Cancers
SECTION VI Hematologic and Oncologic Problems
Chapter 77 Screening for Anemia
Chapter 78 Screening for Sickle Cell Disease and Sickle Cell Trait
Chapter 79 Evaluation of Anemia
Chapter 80 Evaluation of Erythrocytosis (Polycythemia)
Appendix 80-1: Other Myeloproliferative Disorders-Primary Myelofibrosis
Chapter 81 Evaluation of Bleeding Problems and Abnormal Bleeding Studies
Chapter 82 Management of Common Anemias
Appendix 82-1: Management of Asplenia
Chapter 83 Outpatient Oral Anticoagulant Therapy
Chapter 84 Approach to the Patient with Lymphoma
Chapter 85 Approach to the Patient with Metastatic Cancer of Unknown Primary Origin
Chapter 86 Approach to Staging and Monitoring
Chapter 87 Comprehensive Care of the Cancer Patient
Appendix 87-1: Cancer Prevention
Chapter 88 Principles of Cancer Drug Therapy
Chapter 89 Principles of Radiation Therapy
Chapter 90 Assessment and Relief of Chronic Cancer Pain and Palliative Care
Chapter 91 Managing the Gastrointestinal Complications of Cancer and Cancer Treatment
Chapter 92 Complications of Cancer: Oncologic Emergencies, Malignant Effusions, and Paraneoplastic Syndromes
SECTION VII Endocrinologic Problems
Chapter 93 Screening for Type 2 Diabetes Mellitus
Appendix 93-1: Screening for Gestational and Type 1 Diabetes
Chapter 94 Screening for Thyroid Cancer
Chapter 95 Evaluation of Thyroid Nodules.
Chapter 96 Approach to the Patient with Hypercalcemia
Chapter 97 Evaluation of Hypoglycemia
Chapter 98 Evaluation of Hirsutism
Appendix 98-1: Approach to an Incidentally Encountered Adrenal Mass
Chapter 99 Evaluation of Gynecomastia
Chapter 100 Evaluation of Galactorrhea and Hyperprolactinemia
Chapter 101 Evaluation of Suspected Diabetes Insipidus
Chapter 102 Approach to the Patient with Diabetes Mellitus
Chapter 103 Approach to the Patient with Hyperthyroidism
Chapter 104 Approach to the Patient with Hypothyroidism
Chapter 105 Glucocorticoid Therapy
SECTION VIII Gynecologic Problems
Chapter 106 Screening for Breast Cancer
Chapter 107 Screening for Cervical Cancer
Chapter 108 Screening for Ovarian Cancer
Chapter 109 Screening for Endometrial Cancer
Chapter 110 Screening for and Prevention of Intimate Partner Violence
Appendix 110-1: Screening for Firearm Risk
Chapter 111 Approach to the Woman with Abnormal Vaginal Bleeding
Chapter 112 Evaluation and Symptomatic Management of Secondary Amenorrhea
Chapter 113 Evaluation of Breast Masses and Nipple Discharges
Chapter 114 Evaluation of Vulvar Pruritus
Chapter 115 Medical Evaluation of Female Sexual Dysfunction
Chapter 116 Approach to the Patient with Pelvic Pain
Appendix 116-1: Premenstrual Syndrome/Premenstrual Dysphoric Disorder
Chapter 117 Approach to the Patient with an Abnormal Vaginal Discharge
Chapter 118 Approach to the Menopausal Woman
Appendix 118-1: Evaluation of Flushing
Chapter 119 Approach to Fertility Control
Chapter 120 Approach to the Infertile Couple
Chapter 121 Approach to the Woman with an Unplanned Pregnancy
Chapter 122 Management of Breast Cancer
Chapter 123 Management of the Woman with Genital Tract Cancer
SECTION IX Genitourinary Problems
Chapter 124 Screening for Syphilis.
Chapter 125 Screening for Chlamydia and Gonorrhea Infection.