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001431050 020__ $$a9783030657680
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001431050 0247_ $$a10.1007/978-3-030-65768-0$$2doi
001431050 035__ $$aSP(OCoLC)1252918887
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001431050 049__ $$aISEA
001431050 050_4 $$aRC269.7$$b.H48 2021eb
001431050 08204 $$a616.99/407$$223
001431050 24500 $$aThe heterogeneity of cancer metabolism /$$cAnne Le, editor.
001431050 250__ $$aSecond edition.
001431050 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2021]
001431050 300__ $$a1 online resource (1 PDF file (xxiii, 271 pages)) :$$billustrations, portrait.
001431050 336__ $$atext$$btxt$$2rdacontent
001431050 337__ $$acomputer$$bc$$2rdamedia
001431050 338__ $$aonline resource$$bcr$$2rdacarrier
001431050 347__ $$atext file$$bPDF$$2rda
001431050 4901_ $$aAdvances in experimental medicine and biology,$$x2214-8019$$vvolume 1311
001431050 504__ $$aIncludes bibliographical references and index.
001431050 5050_ $$aPart I. Basic Metabolism of Cancer Cells -- Glucose Metabolism in Cancer the Warburg effect and Beyond -- Glutamine Metabolism in Cancer -- The Heterogeneity of Lipid Metabolism in Cancer -- Part II. Heterogeneity of Cancer Metabolism -- The Multifaceted Glioblastoma: from Genomic Alterations to Metabolic Adaptions -- The Intricate Metabolism of Pancreatic Cancers -- The heterogeneity of breast cancer metabolism for therapy -- Non-Hodgkin Lymphoma Metabolism -- The Heterogeneity Metabolism of Renal Cell Carcinomas -- The Heterogeneity Metabolism of Liver Cancer -- Different Tumor Microenvironments Lead to Different Metabolic Phenotypes -- The Intratumoral Heterogeneity of Cancer Metabolism -- Cancer Stem Cells Metabolism -- Metabolism of Immune cells in the Tumor Microenvironment -- Part III. Relationship between Cancer Cells and Cancer-Associated Fibroblasts -- Metabolic Relationship between Cancer-Associated Fibroblasts and Cancer Cells -- Targeting Metabolic Cross Talk between Cancer Cells and Cancer-Associated Fibroblasts -- Part IV. The metabolic interplay between cancer and other diseases -- Diabetes and Cancer: the Epidemiological and Metabolic Associations -- Bridging the Metabolic Parallels between Neurological Diseases and Cancer -- Metabolic Intersection of Cancer and Cardiovascular Diseases: Opportunities for Cancer Therapy -- Index.
001431050 5060_ $$aOpen access$$5GW5XE
001431050 520__ $$aThis open access volume will introduce recent discoveries in the field of cancer metabolism since the publication of the first edition in 2018, providing readers with an up-to-date understanding of developments in the field. Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, the authors delve into the complexity and diversity of cancer metabolism and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies for cancer treatment. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer treatment. This book has four major parts. Part one will cover the basic metabolism of cancer cells, followed by a discussion of the heterogeneity of cancer metabolism in part two. Part three addresses the relationship between cancer cells and cancer-associated fibroblasts, and the new part four will explore the metabolic interplay between cancer and other diseases. This new section makes the book unique from other texts currently available on the market. The second edition will be useful for cancer metabolism researchers, cancer biologists, epidemiologists, physicians, health care professionals in related disciplines, policymakers, marketing and economic strategists, etc. It may also be used in courses such as intro to cancer metabolism, cancer biology, and related biochemistry courses for undergraduate and graduate students. .
001431050 588__ $$aDescription based on online resource; title from PDF title page (viewed October 15, 2021).
001431050 650_0 $$aCancer cells$$xMetabolism.
001431050 650_0 $$aCancer cells$$xMolecular aspects.
001431050 650_0 $$aCancer$$xTreatment.
001431050 650_0 $$aCancer$$xResearch.
001431050 650_6 $$aCellules cancéreuses$$xMétabolisme.
001431050 650_6 $$aCellules cancéreuses$$xAspect moléculaire.
001431050 650_6 $$aCancer$$xTraitement.
001431050 650_6 $$aCancer$$xRecherche.
001431050 650_6 $$aAnticancéreux.
001431050 655_0 $$aElectronic books.
001431050 7001_ $$aLe, Anne,$$eeditor.
001431050 77608 $$iPrint version: $$z9783030657673
001431050 77608 $$iPrint version: $$z9783030657697
001431050 830_0 $$aAdvances in experimental medicine and biology ;$$vvolume 1311.$$x2214-8019
001431050 852__ $$bebk
001431050 85640 $$3Springer Nature$$uhttps://link.springer.com/10.1007/978-3-030-65768-0$$zOnline Access$$91397441.2
001431050 909CO $$ooai:library.usi.edu:1431050$$pGLOBAL_SET
001431050 980__ $$aBIB
001431050 980__ $$aEBOOK
001431050 982__ $$aEbook
001431050 983__ $$aOnline
001431050 994__ $$a92$$bISE