TY - GEN N2 - This book reports on the development and assessment of a novel framework for studying neural interactions (the connectome) and their dynamics (the chronnectome). Using EEG recordings taken during an auditory oddball task performed by 48 patients with schizophrenia and 87 healthy controls, and applying local and network measures, changes in brain activation from pre-stimulus to cognitive response were assessed, and significant differences were observed between the patients and controls. This book investigates the source of the network abnormalities and presents new evidence for the disconnection hypothesis and the aberrant salience hypothesis with regard to schizophrenia. Moreover, it puts forward a novel approach to combining local regularity measures and graph measures in order to characterize schizophrenia brain dynamics, and presents interesting findings on the regularity of brain patterns in healthy control subjects versus patients with schizophrenia. Besides providing new evidence for the disconnection hypothesis, it offers a source of inspiration for future research directions in the field. DO - 10.1007/978-3-030-49900-6 DO - doi AB - This book reports on the development and assessment of a novel framework for studying neural interactions (the connectome) and their dynamics (the chronnectome). Using EEG recordings taken during an auditory oddball task performed by 48 patients with schizophrenia and 87 healthy controls, and applying local and network measures, changes in brain activation from pre-stimulus to cognitive response were assessed, and significant differences were observed between the patients and controls. This book investigates the source of the network abnormalities and presents new evidence for the disconnection hypothesis and the aberrant salience hypothesis with regard to schizophrenia. Moreover, it puts forward a novel approach to combining local regularity measures and graph measures in order to characterize schizophrenia brain dynamics, and presents interesting findings on the regularity of brain patterns in healthy control subjects versus patients with schizophrenia. Besides providing new evidence for the disconnection hypothesis, it offers a source of inspiration for future research directions in the field. T1 - Characterization of neural activity using complex network theory :an application to the study of schizophrenia / AU - Gomez-Pilar, Javier, CN - RC386.6.E86 N1 - "Doctoral Thesis accepted by University of Valladolid, Spain." ID - 1431669 KW - Evoked potentials (Electrophysiology) KW - Neural networks (Neurobiology) KW - Bioengineering. KW - Potentiels évoqués (Électrophysiologie) KW - Réseaux neuronaux (Neurobiologie) KW - Biotechnologie. SN - 9783030499006 SN - 3030499006 SN - 3030498999 SN - 9783030498993 SN - 9783030499013 SN - 3030499014 SN - 9783030499020 SN - 3030499022 TI - Characterization of neural activity using complex network theory :an application to the study of schizophrenia / LK - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-49900-6 UR - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-49900-6 ER -