Endocrine disrupting chemicals-induced metabolic disorders and treatment strategies / Muhammad Sajid Hamid, Akash Kanwal Rehman, Muhammad Zaffar Hashmi, editors.
Hamid, Muhammad Sajid.; Rehman, Akash Kanwai.; Hashmi, Muhammad Zaffar.
2021
RB147
Available Online

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Title Endocrine disrupting chemicals-induced metabolic disorders and treatment strategies / Muhammad Sajid Hamid, Akash Kanwal Rehman, Muhammad Zaffar Hashmi, editors.
ISBN 9783030459239 (electronic bk.)
3030459233 (electronic bk.)
3030459225
9783030459222
DOI https://doi.org/10.1007/978-3-030-45923-9.
Imprint Cham, Switzerland : Springer, [2021]
Language English
Description 1 online resource
Other Standard Identifiers 10.1007/978-3-030-45923-9. doi
10.1007/978-3-030-45
Call Number RB147
Dewey Decimal Classification 616.3/9
Summary This volume offers a detailed and comprehensive analysis of Endocrine Disrupting Chemicals (EDCs), covering their occurrence, exposure to humans and the mechanisms that lead to the parthogenesis of EDCs-induced metabolic disorders. The book is divided into three parts. Part I describes the physiology of the human endocrine system, with special emphasis on various types of metabolic disorders along with risk factors that are responsible for the development of these disorders. Part II addresses all aspects of EDCs, including their role in the induction of various risk factors that are responsible for the development of metabolic disorders. Part III covers up-to-date environmental regulatory considerations and treatment strategies that have been adopted to cure and prevent EDCs-induced metabolic disorders. This section will primarily appeal to clinicians investigating the causes and treatment of metabolic disorders. The text will also be of interest to students and researchers in the fields of Environmental Pharmacology and Toxicology, Environmental Pollution, Pharmaceutical Biochemistry, Biotechnology, and Drug Metabolism/Pharmacokinetics.
Note Includes index.
Access Note Access limited to authorized users.
Added Author Hamid, Muhammad Sajid.
Rehman, Akash Kanwai.
Hashmi, Muhammad Zaffar.
Series Emerging Contaminants and Associated Treatment Technologies Ser.
Available in Other Form Print version: 9783030459222
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Intro
Foreword
Foreword
Endocrine Disrupting Chemicals-Induced Metabolic Disorders
Preface
Acknowledgement
Contents
Contributors
Part I: Introduction to Endocrine System and Metabolic Disorders
Chapter 1: Physiology of Endocrine System and Related Metabolic Disorders
Introduction
Endocrine Glands and Respective Hormones
Pituitary Gland
Anterior Pituitary Gland's Hormones
Growth Hormone
Prolactin
Thyroid Stimulating Hormone (TSH)
Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH)
Adrenocorticotropic Hormone (ACTH)

Posterior Pituitary Gland's Hormones
Antidiuretic Hormone (ADH)
Oxytocin
Thyroid Gland
T3 and T4
Calcitonin
Control System for Thyroid Hormone Secretion
Parathyroid Gland
Parathyroid Hormone (PTH)
Adrenal Gland
Adrenal Medulla
Catecholamines
Adrenal Cortex
Glucocorticoids
Mineralocorticoids
Pineal Gland
The Gonads
Estrogens
Progestogens
Androgen
Pancreas
Insulin
Glucagon
Metabolic Disorders
Thyroid Gland Related
Hyperthyroidism
Signs and Symptoms
Hypothyroidism
Signs and Symptoms
Iodine Deficiency

Parathyroid Gland Related Disorders
Hypoparathyroidism
Signs and Symptoms
Adrenal Gland Related Disorders
Acute Adrenal Insufficiency
Signs and Symptoms
Chronic Adrenal Insufficiency
Signs and Symptoms
Hyperadrenalism (Cushing's Syndrome)
Signs and Symptoms
Pituitary Gland Related Disorders
Acromegaly
Hyperprolactinemia or Galactorrhea
Signs and Symptoms
Erectile Dysfunction (ED) or Impotence
Signs and Symptoms
Central Diabetes Insipidus
Primary Central Diabetes Insipidus
Secondary Central Diabetes Insipidus
Signs and Symptoms

Hypopituitarism
Signs and Symptoms
Growth Hormone Deficiency
Hypothalamus Deficiencies
Prolactin Deficiency
Deficiency of Gonadotropins (FSH and LH)
Pituitary Apoplexy
Pancreas Related Disorders
Diabetes Mellitus
Signs and Symptoms
Hypoglycemia
Signs and Symptoms
Diabetic Ketoacidosis
Signs and Symptoms
Hyperosmolar Hyperglycemic Nonketotic Coma
Conclusion
References
Chapter 2: Impaired Carbohydrate Metabolism in Metabolic Disorders
Introduction
Metabolic Disorders Induced by Impaired Galactose Metabolism
Classic Galactosemia

GALE Deficiency Galactosemia
Cataracts
Metabolic Disorders Induced by Impaired Fructose Metabolism
Essential Fructosuria
Hereditary Fructose Intolerance
Fructose-1,6-Phosphatase Deficiency
Metabolic Disorders Induced by Impaired Glycogen Metabolism
Glycogen Storage Diseases
GSD Type 0
GSD Type I
GSD Type II
GSD Type III
GSD Type IV
GSD Type V
GSD Type VI
GSD Type VII
GSD Type VIII
GSD Type IX
Conclusion
References
Chapter 3: Mitochondrial Dysfunction in Metabolic Disorders
Introduction
Functional and Dysfunctional Mitochondria

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