Historical Perspective of Trauma Induced Coagulopathy
Epidemiology of Hemorrhage-related Mortality
Cell-Mediated Hemostasis
Thrombin-Antithrombin System
Physiology of Hemostasis: Plasmin-antiplasmin system
Thrombin Formation
Platelets
Fibrinogen
Defining and Assessing the Endotheliopathy of Trauma and its Implications on Trauma Induced Coagulopathy and Trauma Related Outcomes
Protein C
Fibrinolysis Dysregulation following Trauma
Complement System
Neutrophils, Inflammation and Innate Immunity in Trauma-Induced Coagulopathy
Disseminated Intravascular Coagulation
Grading Clinical Coagulopathy and Predicting Massive Transfusion
Prothrombin and Partial Thromboplastin Time
Fibrinogen Assays
Rotational Thromboelastometry (ROTEM®)
Thromboelastography (TEG® 5000 and TEG® 6s Hemostasis Analyzers with TEG Manager® Software)
Red Blood Cell Transfusions
Plasma Transfusion
Cryoprecipitate/ Fibrinogen Concentrate Transfusions
Platelet Transfusion
Whole Blood for the Resuscitation of Massively Bleeding Civilian Patients
Adjunct Factor Replacement
Anti-fibrinolytics
Ratio Driven Massive Transfusion Protocols
Goal-Directed Massive Transfusion Management
Pre-Hospital Resuscitation
Venous Thromboembolism after Trauma
Fibrinolysis Shutdown and Venous Thromboembolism
Congenital and Acquired Hypercoagulable States
Pediatrics
Traumatic Brain Injury-Induced Coagulopathy
Blunt Solid Organ Injury: A Call for Timely Chemoprophylaxis in the Setting of Early Hypercoagulability
Pregnancy
Liver Failure
Pulmonary Coagulation in the Pathogenesis of Trauma-Associated Acute Respiratory Distress Syndrome
Management of Chronically Anticoagulated Patients
Randomized Controlled Trials: Informing Clinical Practice for Traumatically Injured Patients
The Quantra® System and SEER Sonorheometry
Dried Plasma for Trauma Resuscitation
Synthetic Blood Substitutes
Flow-Based Coagulation and Fibrinolysis Assays
Animal Models of Coagulopathy
Applications of Viscoelastic Hemostatic Assays at the Site of Care: Considerations and Implications.