001432145 000__ 05519cam\a2200589\i\4500 001432145 001__ 1432145 001432145 003__ OCoLC 001432145 005__ 20230309003426.0 001432145 006__ m\\\\\o\\d\\\\\\\\ 001432145 007__ cr\cn\nnnunnun 001432145 008__ 201031s2021\\\\sz\\\\\\o\\\\\001\0\eng\d 001432145 019__ $$a1225356683$$a1228846090$$a1241066064 001432145 020__ $$a9783030536060$$q(electronic bk.) 001432145 020__ $$a3030536068$$q(electronic bk.) 001432145 020__ $$a9783030536053$$q(e-book) 001432145 020__ $$a303053605X$$q(e-book) 001432145 020__ $$z9783030536053 001432145 0247_ $$a10.1007/978-3-030-53606-0$$2doi 001432145 035__ $$aSP(OCoLC)1202457107 001432145 040__ $$aEBLCP$$beng$$erda$$epn$$cEBLCP$$dUKAHL$$dGW5XE$$dOCLCO$$dGZM$$dUPM$$dOHX$$dOCLCF$$dN$T$$dOCLCQ$$dOCLCO$$dOCLCQ$$dCASUM 001432145 049__ $$aISEA 001432145 050_4 $$aRC647.C55 001432145 08204 $$a616.1/57$$223 001432145 24500 $$aTrauma induced coagulopathy /$$cHunter B. Moore, Matthew D. Neal, Ernest E. Moore, editors. 001432145 250__ $$a2nd ed. 001432145 264_1 $$aCham :$$bSpringer,$$c2021. 001432145 300__ $$a1 online resource (794 pages) 001432145 336__ $$atext$$btxt$$2rdacontent 001432145 337__ $$acomputer$$bc$$2rdamedia 001432145 338__ $$aonline resource$$bcr$$2rdacarrier 001432145 347__ $$atext file 001432145 347__ $$bPDF 001432145 500__ $$aIncludes index. 001432145 5050_ $$aHistorical Perspective of Trauma Induced Coagulopathy -- Epidemiology of Hemorrhage-related Mortality -- Cell-Mediated Hemostasis -- Thrombin-Antithrombin System -- Physiology of Hemostasis: Plasmin-antiplasmin system -- Thrombin Formation -- Platelets -- Fibrinogen -- Defining and Assessing the Endotheliopathy of Trauma and its Implications on Trauma Induced Coagulopathy and Trauma Related Outcomes -- Protein C -- Fibrinolysis Dysregulation following Trauma -- Complement System -- Neutrophils, Inflammation and Innate Immunity in Trauma-Induced Coagulopathy -- Disseminated Intravascular Coagulation -- Grading Clinical Coagulopathy and Predicting Massive Transfusion -- Prothrombin and Partial Thromboplastin Time -- Fibrinogen Assays -- Rotational Thromboelastometry (ROTEM®) -- Thromboelastography (TEG® 5000 and TEG® 6s Hemostasis Analyzers with TEG Manager® Software) -- Red Blood Cell Transfusions -- Plasma Transfusion -- Cryoprecipitate/ Fibrinogen Concentrate Transfusions -- Platelet Transfusion -- Whole Blood for the Resuscitation of Massively Bleeding Civilian Patients -- Adjunct Factor Replacement -- Anti-fibrinolytics -- Ratio Driven Massive Transfusion Protocols -- Goal-Directed Massive Transfusion Management -- Pre-Hospital Resuscitation -- Venous Thromboembolism after Trauma -- Fibrinolysis Shutdown and Venous Thromboembolism -- Congenital and Acquired Hypercoagulable States -- Pediatrics -- Traumatic Brain Injury-Induced Coagulopathy -- Blunt Solid Organ Injury: A Call for Timely Chemoprophylaxis in the Setting of Early Hypercoagulability -- Pregnancy -- Liver Failure -- Pulmonary Coagulation in the Pathogenesis of Trauma-Associated Acute Respiratory Distress Syndrome -- Management of Chronically Anticoagulated Patients -- Randomized Controlled Trials: Informing Clinical Practice for Traumatically Injured Patients -- The Quantra® System and SEER Sonorheometry -- Dried Plasma for Trauma Resuscitation -- Synthetic Blood Substitutes -- Flow-Based Coagulation and Fibrinolysis Assays -- Animal Models of Coagulopathy -- Applications of Viscoelastic Hemostatic Assays at the Site of Care: Considerations and Implications. 001432145 506__ $$aAccess limited to authorized users. 001432145 520__ $$aThe first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy. 001432145 588__ $$aDescription based on print version record. 001432145 650_0 $$aBlood coagulation disorders. 001432145 650_0 $$aTraumatology. 001432145 650_6 $$aSang$$xTroubles de la coagulation. 001432145 650_6 $$aTraumatologie. 001432145 655_0 $$aElectronic books. 001432145 7001_ $$aMoore, Hunter B. 001432145 7001_ $$aNeal, Matthew D. 001432145 7001_ $$aMoore, Ernest Eugene. 001432145 77608 $$iPrint version:$$tTrauma induced coagulopathy.$$b2nd ed.$$dCham : Springer, 2021$$z9783030536060 001432145 852__ $$bebk 001432145 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-53606-0$$zOnline Access$$91397441.1 001432145 909CO $$ooai:library.usi.edu:1432145$$pGLOBAL_SET 001432145 980__ $$aBIB 001432145 980__ $$aEBOOK 001432145 982__ $$aEbook 001432145 983__ $$aOnline 001432145 994__ $$a92$$bISE