001432180 000__ 06144cam\a2200625\a\4500 001432180 001__ 1432180 001432180 003__ OCoLC 001432180 005__ 20230309003428.0 001432180 006__ m\\\\\o\\d\\\\\\\\ 001432180 007__ cr\un\nnnunnun 001432180 008__ 201031s2021\\\\sz\\\\\\o\\\\\000\0\eng\d 001432180 019__ $$a1198976902$$a1204152570$$a1237459258$$a1241533998 001432180 020__ $$a9783030511609$$q(electronic bk.) 001432180 020__ $$a303051160X$$q(electronic bk.) 001432180 020__ $$z3030511588 001432180 020__ $$z9783030511586 001432180 0247_ $$a10.1007/978-3-030-51160-9$$2doi 001432180 035__ $$aSP(OCoLC)1202468210 001432180 040__ $$aEBLCP$$beng$$epn$$cEBLCP$$dYDX$$dGW5XE$$dOCLCO$$dERF$$dSFB$$dOCLCF$$dUKMGB$$dOCL$$dDKU$$dOCLCO$$dN$T$$dOCLCQ$$dOCLCO$$dOCLCQ$$dCASUM 001432180 049__ $$aISEA 001432180 050_4 $$aRC281.C4 001432180 08204 $$a618.92/994$$223 001432180 24500 $$aSarcomas of bone and soft tissues in children and adolescents /$$cCarola A.S. Arndt, editor. 001432180 260__ $$aCham :$$bSpringer,$$c2021. 001432180 300__ $$a1 online resource (181 pages) 001432180 336__ $$atext$$btxt$$2rdacontent 001432180 337__ $$acomputer$$bc$$2rdamedia 001432180 338__ $$aonline resource$$bcr$$2rdacarrier 001432180 4901_ $$aPediatric Oncology 001432180 500__ $$a6.4.2 Other "Adult-Type" Sarcomas (Fibrosarcoma, Liposarcoma, Mesenchymal Chondrosarcoma, PECOMA, Leiomyosarcoma, Epithelioid Sarcoma, Clear Cell Sarcoma, Angiosarcoma, Undifferentiated Sarcoma) 001432180 504__ $$aReferences-2: Sarcoma Pathology and Biology-2.1 Rhabdomyosarcoma-2.1.1 Pathology-2.1.1.1 Alveolar Rhabdomyosarcoma-2.1.1.2 Embryonal Rhabdomyosarcoma-2.1.1.3 Spindle Cell/Sclerosing Rhabdomyosarcoma-2.1.2 Biology-2.1.2.1 Fusion-Positive Rhabdomyosarcoma-2.1.2.2 Fusion-Negative Rhabdomyosarcoma-2.1.2.3 Spindle Cell/Sclerosing Rhabdomyosarcoma-2.2 Ewing Sarcoma-2.2.1 Pathology-2.2.2 Biology-2.2.3 Ewing-Like Sarcomas-2.2.3.1 CIC-Rearranged Sarcomas-2.2.3.2 Ewing-Like Sarcoma with BCOR Rearrangements-2.3 Osteosarcoma. 001432180 5050_ $$aIntro -- Contents -- 1: Epidemiology of Bone and Soft Tissue Sarcomas -- 1.1 Introduction -- 1.2 Descriptive Epidemiology -- 1.2.1 Osteosarcoma -- 1.2.2 Ewing Sarcoma -- 1.2.3 Rhabdomyosarcoma (RMS) -- 1.2.4 Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) -- 1.3 Environmental (Non-genetic) Risk Factors -- 1.3.1 Osteosarcoma -- 1.3.1.1 Growth and Development -- 1.3.1.2 Exogenous Exposures -- 1.3.2 Ewing Sarcoma -- 1.3.3 RMS -- 1.3.4 NRSTS -- 1.4 Germline Genetic Risk Factors -- 1.4.1 Osteosarcoma -- 1.4.2 Ewing Sarcoma -- 1.4.3 RMS -- 1.4.4 NRSTS -- 1.5 Conclusion 001432180 5058_ $$a2.3.1 Pathology -- 2.3.2 Biology -- 2.4 Non-rhabdomyosarcoma Soft Tissue Sarcomas -- 2.4.1 Alveolar Soft Part Sarcoma -- 2.4.1.1 Pathology -- 2.4.1.2 Biology -- 2.4.2 Clear Cell Sarcoma of Soft Tissue -- 2.4.2.1 Pathology -- 2.4.2.2 Biology -- 2.4.3 Desmoid Tumor -- 2.4.3.1 Pathology -- 2.4.3.2 Biology -- 2.4.4 Desmoplastic Small Round Cell Tumor -- 2.4.4.1 Pathology -- 2.4.4.2 Biology -- 2.4.5 Malignant Peripheral Nerve Sheath Tumor -- 2.4.5.1 Pathology -- 2.4.5.2 Biology -- 2.4.6 Synovial Sarcoma -- 2.4.6.1 Pathology -- 2.4.6.2 Biology -- 2.4.7 Malignant Rhabdoid Tumor 001432180 5058_ $$a2.4.7.1 Pathology -- 2.4.7.2 Biology -- 2.4.8 NTRK-Fusion Sarcomas -- 2.4.8.1 Pathology -- 2.4.8.2 Biology -- References -- 3: Staging and Imaging of Sarcoma -- 3.1 Staging of RMS and NRSTS -- 3.2 Staging of Nonrhabdomyosarcomatous Soft Tissue Tumors (NRSTS) -- 3.3 Staging of Bone Sarcomas -- 3.4 Imaging and Staging Procedures -- References -- 4: Multi-institutional Trials for Patients with Rhabdomyosarcoma: Lessons from North American Studies from 1967 Through 1997 -- 4.1 Introduction -- 4.2 The First 30 Years, 1970-2000 -- 4.2.1 The IRS Era, 1972-1997 -- References 001432180 5058_ $$a5: Treatment of Rhabdomyosarcoma -- 5.1 Introduction -- 5.2 Initial Evaluation -- 5.3 Treatment Assignment -- 5.4 Treatment -- 5.4.1 North American Perspective -- 5.4.2 European Perspective -- 5.5 Future Directions -- References -- 6: Current Approaches to Therapy: Soft Tissue Sarcomas Other than Rhabdomyosarcoma in Children and Adolescents -- 6.1 Introduction -- 6.2 Local Therapy -- 6.2.1 Surgery -- 6.2.2 Radiotherapy -- 6.3 Conventional Chemotherapy -- 6.4 Specific Therapy for Diseases -- 6.4.1 Synovial Sarcoma 001432180 506__ $$aAccess limited to authorized users. 001432180 520__ $$aThis book is a comprehensive and up-to-date compendium on all aspects of sarcomas of bone and soft tissues in childhood and adolescence. After introductory chapters on the history, epidemiology, and biology of pediatric sarcomas, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. The pathology and biology of this diverse group of tumors are extensively reviewed. Promising new treatment approaches are discussed, and strategies for the development of new agents are appraised. The major common pediatric sarcomas, including osteosarcoma, Ewing sarcoma, rhabdomyosarcoma and non-rhabdomyosarcoma soft tissue sarcoma, are covered in detail. The authors are internationally recognized experts who offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of childhood and adolescent sarcomas and will prove invaluable to specialists, generalists, and trainees alike. 001432180 588__ $$aDescription based on print version record. 001432180 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed December 2, 2020). 001432180 650_0 $$aCancer in children. 001432180 650_0 $$aBone$$xCancer. 001432180 650_0 $$aSoft tissue tumors. 001432180 650_6 $$aCancer chez l'enfant. 001432180 650_6 $$aOs$$xCancer. 001432180 650_6 $$aTissu mou$$xTumeurs. 001432180 655_0 $$aElectronic books. 001432180 7001_ $$aArndt, Carola A. S. 001432180 77608 $$iPrint version:$$aArndt, Carola A.S.$$tSarcomas of Bone and Soft Tissues in Children and Adolescents.$$dCham : Springer International Publishing AG, ©2020$$z9783030511586 001432180 830_0 $$aPediatric oncology (Series) 001432180 852__ $$bebk 001432180 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-51160-9$$zOnline Access$$91397441.1 001432180 909CO $$ooai:library.usi.edu:1432180$$pGLOBAL_SET 001432180 980__ $$aBIB 001432180 980__ $$aEBOOK 001432180 982__ $$aEbook 001432180 983__ $$aOnline 001432180 994__ $$a92$$bISE