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001432374 001__ 1432374
001432374 003__ OCoLC
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001432374 020__ $$a9783030531683$$q(electronic bk.)
001432374 020__ $$a3030531686$$q(electronic bk.)
001432374 020__ $$a3030531678
001432374 020__ $$a9783030531676
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001432374 020__ $$z9783030531676$$q(print)
001432374 0243_ $$a9783030531676
001432374 0247_ $$a10.1007/978-3-030-53168-3$$2doi
001432374 035__ $$aSP(OCoLC)1204139193
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001432374 08204 $$a616.8/04757$$223
001432374 08204 $$a616.8047575
001432374 24500 $$aPET and SPECT in neurology /$$cRudi A.J.O. Dierckx, Andreas Otte, Erik F.J. de Vries, Aren van Waarde, editors ; Klaus L. Leenders, guest editor.
001432374 250__ $$aSecond edition.
001432374 264_1 $$aCham :$$bSpringer,$$c[2021]
001432374 300__ $$a1 online resource (xiii, 1289 pages) :$$b$$b illustrations
001432374 336__ $$atext$$btxt$$2rdacontent
001432374 337__ $$acomputer$$bc$$2rdamedia
001432374 338__ $$aonline resource$$bcr$$2rdacarrier
001432374 347__ $$atext file
001432374 347__ $$bPDF
001432374 504__ $$aIncludes bibliographical references.
001432374 5050_ $$aIntro -- Foreword -- Preface -- Contents -- Part I: Basics -- 1: Nuclear Medicine Imaging Tracers for Neurology -- 1.1 Introduction -- 1.2 Glucose Consumption -- 1.3 Translocator Protein TSPO -- 1.4 GABA Receptor -- 1.5 Dopaminergic System -- 1.5.1 Dopamine Transporter (DAT) -- 1.5.2 D1 Receptor -- 1.5.3 D2 Receptor -- 1.5.4 D2/D3 Agonists -- 1.6 Beta-Amyloid Deposition -- 1.7 NMDA Receptor, Glycine Transport -- 1.8 P-Glycoprotein -- 1.9 Cholinergic System -- 1.10 Metabotropic Glutamate-5 Receptor -- 1.11 Vesicular Monoamine Transporter -- 1.12 Adenosine Receptors
001432374 5058_ $$a1.13 Serotonergic System -- 1.13.1 Serotonin Transporter -- 1.13.2 5-HT Receptor Ligands -- 1.14 Nonadrenergic System -- 1.15 Opioid Receptors -- 1.16 Monoamine Oxidase -- 1.17 SV2A Receptors -- 1.18 Sigma Receptors -- 1.19 Tau Protein Deposition -- 1.20 Phosphodiesterase -- 1.21 P2X7 Receptor -- 1.22 (Re)Myelination -- 1.23 Cannabinoid Receptors -- 1.24 Conclusions -- References -- 2: Tracer Kinetic Modelling -- 2.1 Introduction -- 2.2 Principles of Modelling -- 2.3 Single-Tissue Compartment Model -- 2.4 Principles and Practice of Quantification
001432374 5058_ $$a2.5 An Example: Measurement of CBF Using [15O]H2O -- 2.6 Two-Tissue Compartment Model -- 2.7 Reference Tissue Models -- 2.8 Parametric Methods -- 2.9 Conclusions -- References -- 3: Quantification in Brain SPECT: Noninvasive Cerebral Blood Flow Measurements Using 99mTc-Labeled Tracers -- 3.1 Introduction -- 3.2 Method -- 3.2.1 Theory of Graphical Analysis -- 3.2.2 Brain Perfusion Index (BPI) -- 3.2.3 Comparison of BPI and CBF Values Measured by Other Invasive Methods -- 3.2.4 Alternative Approach to Estimation of BPI -- 3.2.5 Calculation of Regional CBF from BPI
001432374 5058_ $$a3.2.6 Consecutive rCBF Measurements at Baseline and Acetazolamide Challenge -- 3.3 Clinical Application -- 3.3.1 Cerebrovascular Diseases -- 3.3.2 Heart Failure -- 3.3.3 Idiopathic Normal Pressure Hydrocephalus -- 3.3.4 Neurodegenerative Disorders -- 3.3.5 Mood Disorders -- 3.3.6 Other Neuropsychiatric Diseases -- 3.4 Conclusion -- References -- 4: From Positron to Pattern: A Conceptual and Practical Overview of 18F-FDG PET Imaging and Spatial Covariance Analysis -- 4.1 18F-FDG PET Imaging -- 4.1.1 Basic Concepts in PET -- 4.1.2 18F-FDG PET Imaging
001432374 5058_ $$a4.1.3 Studying Brain Function with 18F-FDG PET -- 4.2 Analysis of Resting-State 18F-FDG PET Images -- 4.2.1 Image Registration -- 4.2.2 Normalization -- 4.2.3 Analysis of Variance and Covariance -- 4.2.4 Principal Component Analysis -- 4.3 SSM PCA -- 4.3.1 Defining the Data -- 4.3.2 Normalization with the Scaled Subprofile Model (SSM) -- 4.3.3 Calculating Eigenvectors from a Covariance Matrix -- 4.3.4 Calculating Subject Scores and Selecting Disease-Related Components -- 4.3.5 Prospective Application of the Pattern -- 4.3.6 Validation
001432374 506__ $$aAccess limited to authorized users.
001432374 520__ $$a"This book provides a comprehensive overview of the use of PET and SPECT in not only classic neurodegenerative disorders but also cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders, and inflammatory and infectious diseases of the CNS. The new edition has been revised and updated to reflect recent advances and includes additional chapters, for example on the use of artificial intelligence and machine learning in imaging data analysis, the study of brain connectivity using PET and SPECT images, and the role of PET imaging in modulation of brain functioning by deep brain stimulation. The authors are renowned experts whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state of the art compendium will be invaluable for neurologists and radiologists/nuclear medicine specialists and will also be informative for interested general practitioners and geriatricians. Companion volumes on PET and SPECT in psychiatry and in neurobiological systems complete a trilogy."--Publisher's description
001432374 588__ $$aDescription based on print version record.
001432374 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed January 12, 2021).
001432374 650_0 $$aNervous system$$xDiseases$$xTomography.
001432374 650_0 $$aTomography, Emission.
001432374 650_6 $$aSystème nerveux$$xMaladies.
001432374 650_6 $$aTomographie par émission.
001432374 655_0 $$aElectronic books.
001432374 7001_ $$aDierckx, Rudi A. J. O.
001432374 7001_ $$aOtte, Andreas P.,$$d1967-
001432374 7001_ $$aVries, Erik F. J. de.
001432374 7001_ $$aWaarde, Aren van.
001432374 7001_ $$aLeenders, K. L.
001432374 77608 $$iPrint version:$$aDierckx, Rudi A.J.O.$$tPET and SPECT in Neurology.$$dCham : Springer International Publishing AG, ©2020$$z9783030531676
001432374 852__ $$bebk
001432374 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-53168-3$$zOnline Access$$91397441.1
001432374 909CO $$ooai:library.usi.edu:1432374$$pGLOBAL_SET
001432374 980__ $$aBIB
001432374 980__ $$aEBOOK
001432374 982__ $$aEbook
001432374 983__ $$aOnline
001432374 994__ $$a92$$bISE