TY - GEN N2 - "This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch's role in the development of the embryo to the Notch signaling pathway's role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch's role in senescence, the regulation of Notch signaling by microRNAs, Notch's role in the microbiome, diet and its influence on Notch signaling and more. Taken as a whole, with its companion books -- Notch Signaling and Embryologic Development and Molecular Basis of Notch Signaling - this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students"--Publisher's description DO - 10.1007/978-3-030-55031-8 DO - doi AB - "This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch's role in the development of the embryo to the Notch signaling pathway's role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch's role in senescence, the regulation of Notch signaling by microRNAs, Notch's role in the microbiome, diet and its influence on Notch signaling and more. Taken as a whole, with its companion books -- Notch Signaling and Embryologic Development and Molecular Basis of Notch Signaling - this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students"--Publisher's description T1 - Notch signaling in embryology and cancer. AU - Reichrath, J. AU - Reichrath, Sandra, ET - [Second edition] VL - volume 1287 CN - RC268.4 N1 - Edition statement from preface. N1 - Updated and expanded edition of Notch signaling in embryology and cancer published by Landes and Springer in 2012 in Advances in experimental medicine and biology, volume 727. Volume 1 is Molecular biology of Notch signaling, Volume II is Notch signaling in embryology, and Volume III is Notch signaling in cancer. ID - 1432454 KW - Cancer KW - Cancer KW - Notch genes. KW - Cancer KW - Cytology. KW - Embryology. KW - Cellular signal transduction. KW - Cancer KW - Cancer KW - Gènes Notch. KW - Cancer KW - Cytologie. KW - Transduction du signal cellulaire. SN - 9783030550318 SN - 3030550311 TI - Notch signaling in embryology and cancer. LK - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-55031-8 UR - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-55031-8 ER -