001432454 000__ 05708cam\a2200793\i\4500 001432454 001__ 1432454 001432454 003__ OCoLC 001432454 005__ 20230309003443.0 001432454 006__ m\\\\\o\\d\\\\\\\\ 001432454 007__ cr\un\nnnunnun 001432454 008__ 201008t20212021sz\a\\\\ob\\\\001\0\eng\d 001432454 019__ $$a1161115821$$a1199891408$$a1202463922$$a1228843671$$a1237412362$$a1241066028 001432454 020__ $$a9783030550318$$q(electronic book) 001432454 020__ $$a3030550311$$q(electronic book) 001432454 020__ $$z9783030550301$$q(hardcover) 001432454 020__ $$z3030550303$$q(hardcover) 001432454 0247_ $$a10.1007/978-3-030-55031-8$$2doi 001432454 035__ $$aSP(OCoLC)1204152088 001432454 040__ $$aSFB$$beng$$erda$$epn$$cSFB$$dOCLCO$$dYDX$$dOCLCO$$dOCLCF$$dGW5XE$$dEBLCP$$dUKAHL$$dTEF$$dOCL$$dOCLCO$$dUPM$$dBDX$$dYDXIT$$dOCLCA$$dMMU$$dOCLCO$$dOCLCQ$$dOCLCO$$dCOM$$dOCL$$dOCLCQ$$dCASUM 001432454 049__ $$aISEA 001432454 050_4 $$aRC268.4 001432454 08204 $$a616.9/940421$$223 001432454 08204 $$a614.5999$$223 001432454 24500 $$aNotch signaling in embryology and cancer.$$nVolume III,$$pNotch signaling in cancer /$$cJörg Reichrath, Sandra Reichrath, editors. 001432454 2463_ $$aNotch signaling in cancer 001432454 250__ $$a[Second edition] 001432454 264_1 $$aCham :$$bSpringer,$$c[2021] 001432454 264_4 $$c©2021 001432454 300__ $$a1 online resource (xvii, 228 pages) :$$billustrations (some color) 001432454 336__ $$atext$$btxt$$2rdacontent 001432454 337__ $$acomputer$$bc$$2rdamedia 001432454 338__ $$aonline resource$$bcr$$2rdacarrier 001432454 347__ $$atext file 001432454 347__ $$bPDF 001432454 4901_ $$aAdvances in experimental medicine and biology,$$x2214-8019 ;$$vvolume 1287 001432454 500__ $$aEdition statement from preface. 001432454 500__ $$aUpdated and expanded edition of Notch signaling in embryology and cancer published by Landes and Springer in 2012 in Advances in experimental medicine and biology, volume 727. Volume 1 is Molecular biology of Notch signaling, Volume II is Notch signaling in embryology, and Volume III is Notch signaling in cancer. 001432454 504__ $$aIncludes bibliographical references and index. 001432454 5050_ $$aNotch signaling in prevention ant therapy: fighting cancer with a two-sided sword -- Transcription factor RBPJ as a molecular switch in regulating the Notch response -- Unraveling of hidden secrets: the tumour suppressor lethal (2) giant discs (Lgd)/CC2D1, Notch signaling and cancer -- Notch and endometrial cancer -- Notch and esophageal squamous cell carcinoma -- Notch signaling and liver cancer -- Notch in head and neck cancer -- Notch signaling and human papillomavirus-associated oral tumorigenesis -- The impact of Notch signaling for carcinogenesis and progression of non-melanoma skin cancer: lessons learned from cancer stem cells, tumor angiogenesis, and beyond -- Notch signaling in thyroid cancer -- The relevance of Notch signaling in cancer progression -- Notch signaling and the breast cancer microenvironment -- Notch pathway: a journey from Notching phenotypes to cancer immunotherapy. 001432454 506__ $$aAccess limited to authorized users. 001432454 520__ $$a"This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch's role in the development of the embryo to the Notch signaling pathway's role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch's role in senescence, the regulation of Notch signaling by microRNAs, Notch's role in the microbiome, diet and its influence on Notch signaling and more. Taken as a whole, with its companion books -- Notch Signaling and Embryologic Development and Molecular Basis of Notch Signaling - this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students"--Publisher's description 001432454 588__ $$aOnline resource; title from electronic title page (ProQuest Ebook Central, viewed on June 22, 2021). 001432454 650_0 $$aCancer$$xMolecular aspects. 001432454 650_0 $$aCancer$$xGenetic aspects. 001432454 650_0 $$aNotch genes. 001432454 650_0 $$aCancer$$xResearch. 001432454 650_0 $$aCytology. 001432454 650_0 $$aEmbryology. 001432454 650_0 $$aCellular signal transduction. 001432454 650_6 $$aCancer$$xAspect moléculaire. 001432454 650_6 $$aCancer$$xAspect génétique. 001432454 650_6 $$aGènes Notch. 001432454 650_6 $$aCancer$$xRecherche. 001432454 650_6 $$aCytologie. 001432454 650_6 $$aTransduction du signal cellulaire. 001432454 655_0 $$aElectronic books. 001432454 7001_ $$aReichrath, J.$$q(Jörg),$$d1962-$$eeditor. 001432454 7001_ $$aReichrath, Sandra,$$d1974-$$eeditor. 001432454 7300_ $$iPreceded by:$$aNotch signaling in embryology and cancer. 001432454 7300_ $$iCompanion to:$$aNotch signaling in embryology and cancer.$$nVolume I,$$pMolecular biology of Notch signaling. 001432454 7300_ $$iCompanion to:$$aNotch signaling in embryology and cancer.$$nVolume II,$$pNotch signaling in embryology. 001432454 77608 $$iPrint version:$$tNotch signaling in embryology and cancer.$$bRevised second edition.$$dCham, Switzerland : Springer, [2021]$$z9783030550301$$w(OCoLC)1230869468 001432454 830_0 $$aAdvances in experimental medicine and biology ;$$v1287.$$x0065-2598 001432454 852__ $$bebk 001432454 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-55031-8$$zOnline Access$$91397441.1 001432454 909CO $$ooai:library.usi.edu:1432454$$pGLOBAL_SET 001432454 980__ $$aBIB 001432454 980__ $$aEBOOK 001432454 982__ $$aEbook 001432454 983__ $$aOnline 001432454 994__ $$a92$$bISE