001433022 000__ 06331cam\a2200649\i\4500 001433022 001__ 1433022 001433022 003__ OCoLC 001433022 005__ 20230309003545.0 001433022 006__ m\\\\\o\\d\\\\\\\\ 001433022 007__ cr\cn\nnnunnun 001433022 008__ 201221t20212021sz\\\\\\ob\\\\001\0\eng\d 001433022 019__ $$a1202052477$$a1204141409$$a1237455103 001433022 020__ $$a9783030563875$$q(electronic bk.) 001433022 020__ $$a3030563871$$q(electronic bk.) 001433022 020__ $$z9783030563868 001433022 020__ $$z3030563863 001433022 0247_ $$a10.1007/978-3-030-56387-5$$2doi 001433022 035__ $$aSP(OCoLC)1227522655 001433022 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dN$T$$dOCLCO$$dGW5XE$$dEBLCP$$dYDX$$dUKAHL$$dOCLCF$$dESU$$dSFB$$dOCLCQ$$dOCLCO$$dCOM$$dOCLCQ$$dCASUM 001433022 049__ $$aISEA 001433022 050_4 $$aRG483.P44 001433022 08204 $$a617.5/5$$223 001433022 24500 $$aChronic pelvic pain and pelvic dysfunctions :$$bassessment and multidisciplinary approach /$$cAlessandro Giammò, Antonella Biroli, editors. 001433022 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2021] 001433022 264_4 $$c©2021 001433022 300__ $$a1 online resource 001433022 336__ $$atext$$btxt$$2rdacontent 001433022 337__ $$acomputer$$bc$$2rdamedia 001433022 338__ $$aonline resource$$bcr$$2rdacarrier 001433022 4901_ $$aUrodynamics, Neurourology and Pelvic Floor Dysfunctions Ser. 001433022 504__ $$aIncludes bibliographical references and index. 001433022 5050_ $$aIntro -- Foreword -- Preface -- Contents -- Part I: The Nervous System and Pain -- 1: Introduction to Pain -- 1.1 Anatomy of Pain Pathways -- 1.2 Physiology of Pain -- 1.3 Classification of Pain -- 1.4 Conclusion -- References -- 2: Neurophysiology of Visceral Pain -- 2.1 Introduction -- 2.2 Clinical Presentation of Visceral Pain -- 2.2.1 True Visceral Pain -- 2.2.2 Referred Pain and Hyperalgesia (Viscero-somatic Convergence) -- 2.2.3 Visceral Hyperalgesia -- 2.2.4 Viscero-visceral Hyperalgesia -- 2.3 Pathophysiology of Visceral Pain 001433022 5058_ $$a2.3.1 Visceral Nociceptors and the Primary Afferent -- 2.3.2 Peripheral Sensitization -- 2.3.2.1 Transient Receptor Potential Vallinoid -- 2.3.3 The Role of Dorsal Columns -- 2.3.4 Central Processing -- 2.3.5 Central Sensitization -- 2.3.6 Descending Control of Visceral Pain -- 2.3.7 The Role of Gut Microbiota in Visceral Pain -- 2.4 Conclusion -- References -- 3: Neuroinflammation and Chronic Pelvic Pain Syndrome -- 3.1 Chronic Pelvic Pain -- 3.2 Neuroinflammation -- 3.3 Microglia and Astrocytes in Chronic Pain -- 3.4 Molecular Mediators in Chronic Pain 001433022 5058_ $$a3.5 Targeting Excessive Inflammation as a Therapy for Neuropathic Pain -- 3.6 Clinical Significance and Future Perspectives -- 3.7 PEA -- 3.8 Polydatin -- 3.9 PEA and Polydatin as Future Treatment of Chronic Pelvic Pain -- References -- Part II: The Organs, Pelvic Functions and Pain -- 4: Chronic Pelvic Pain and Chronic Pelvic Pain Syndrome: Classification and Epidemiology -- 4.1 Introduction -- 4.2 Definitions -- 4.3 Classification -- 4.3.1 Classification of CPPS -- 4.4 Dyspareunia -- 4.5 Perineal Pain Syndrome -- 4.6 Epidemiology -- References 001433022 5058_ $$a5: Bladder Pain Syndrome/Interstitial Cystitis -- 5.1 Introduction -- 5.2 Definition -- 5.3 Epidemiology -- 5.4 Non-bladder Syndromes (NBS) -- 5.5 Etiology and Pathogenesis -- 5.5.1 Infection -- 5.5.2 Mastocytosis -- 5.5.3 Dysfunctional Bladder Epithelium -- 5.5.4 Neurogenic Inflammation -- 5.5.5 Reduced Vascularization -- 5.5.6 Pelvic Floor Dysfunction -- 5.5.7 Autoimmunity -- 5.6 Diagnosis -- 5.7 O'Leary Sant Symptom and Pain Index -- 5.8 Gynecological Associated/Confusable Disease -- 5.9 Treatment -- 5.10 Multimodal Medical Therapy -- 5.10.1 First Line: Conservative Therapy 001433022 5058_ $$a5.10.2 Second Line: Medical Therapy -- 5.11 Oral Therapy -- 5.11.1 Pain Modulators -- 5.11.2 Analgesics (Grade of Recommendation: C-Level of Evidence: 4) -- 5.11.2.1 Tricyclic Antidepressants(TCAs) -- Doxepin, Desipramine, Duloxetine -- 5.11.3 Protection of the Mucosal Surface -- 5.11.3.1 Antihistamines -- 5.11.3.2 Immunosuppressant -- 5.11.3.3 Other Oral Medications -- 5.12 Intravesical Instillation or Bladder Wall Injection -- 5.12.1 Third to Fourth Line: Procedural Intervention -- 5.13 Conclusions -- References 001433022 506__ $$aAccess limited to authorized users. 001433022 520__ $$aThis book provides readers with a holistic approach to chronic pelvic pain which is an extremely complex condition with associated pelvic dysfunctions. This approach significantly facilitates and accelerates the clinical assessment and subsequent follow-up. The pathophysiologic mechanisms involving the nervous system, the pelvic organs and the pelvic floor are discussed, deepening the possible implications on mind, sexuality and pelvic dysfunctions. Evaluation and diagnosis are examined for different types of syndromes. Moreover, since the Bladder Pain Syndrome and the Interstitial Cystitis are main causes of pelvic pain, an original diagnostic approach is proposed specifically for these conditions. In order to deliver the best clinical outcomes, this new system provides a multidisciplinary approach, both in the diagnostic phase and in the therapeutic phase The most recent therapies for chronic pelvic pain following a multidisciplinary approach have been described. As such, the book content will greatly benefit all professionals dealing with this debilitating disease, supporting them in their daily clinical practice. 001433022 588__ $$aOnline resource; title from PDF title page (EBSCO, viewed December 22, 2020). 001433022 650_0 $$aPelvic pain$$xDiagnosis. 001433022 650_0 $$aPelvic pain$$xTreatment. 001433022 650_0 $$aChronic pain. 001433022 650_0 $$aGenerative organs, Female$$xDiseases. 001433022 650_6 $$aDouleur pelvienne$$xTraitement. 001433022 650_6 $$aDouleur chronique. 001433022 650_6 $$aOrganes génitaux femelles$$xMaladies. 001433022 655_0 $$aElectronic books. 001433022 7001_ $$aGiammò, Alessandro,$$eeditor. 001433022 7001_ $$aBiroli, Antonella,$$eeditor. 001433022 77608 $$iPrint version:$$aGiammò, Alessandro$$tChronic Pelvic Pain and Pelvic Dysfunctions : Assessment and Multidisciplinary Approach$$dCham : Springer International Publishing AG,c2020$$z9783030563868 001433022 830_0 $$aUrodynamics, Neurourology and Pelvic Floor Dysfunctions Ser. 001433022 852__ $$bebk 001433022 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-56387-5$$zOnline Access$$91397441.1 001433022 909CO $$ooai:library.usi.edu:1433022$$pGLOBAL_SET 001433022 980__ $$aBIB 001433022 980__ $$aEBOOK 001433022 982__ $$aEbook 001433022 983__ $$aOnline 001433022 994__ $$a92$$bISE