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001433123 001__ 1433123
001433123 003__ OCoLC
001433123 005__ 20230309003550.0
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001433123 007__ cr\nn\nnnunnun
001433123 008__ 201208s2021\\\\sz\a\\\\o\\\\\001\0\eng\d
001433123 019__ $$a1226532634$$a1226587545$$a1228844596$$a1229917363$$a1241066455$$a1249945019
001433123 020__ $$a9783030562670$$q(electronic bk.)
001433123 020__ $$a3030562670$$q(electronic bk.)
001433123 020__ $$z9783030562663
001433123 020__ $$z3030562662
001433123 0247_ $$a10.1007/978-3-030-56267-0$$2doi
001433123 035__ $$aSP(OCoLC)1228649088
001433123 040__ $$aSFB$$beng$$erda$$epn$$cSFB$$dEBLCP$$dOCLCO$$dOCLCF$$dGW5XE$$dOCLCO$$dUPM$$dBDX$$dYDX$$dDKU$$dOHX$$dLEATE$$dOCL$$dOCLCQ$$dOCLCO$$dCOM$$dN$T$$dOCLCQ$$dCASUM
001433123 049__ $$aISEA
001433123 050_4 $$aRC271.R3
001433123 08204 $$a616.99/40642$$223
001433123 24500 $$aLocoregional radionuclide cancer therapy :$$bclinical and scientific aspects /$$cFranklin C.L. Wong, editor.
001433123 264_1 $$aCham :$$bSpringer,$$c[2021]
001433123 300__ $$a1 online resource (xii, 268 pages) :$$billustrations (some color)
001433123 336__ $$atext$$btxt$$2rdacontent
001433123 337__ $$acomputer$$bc$$2rdamedia
001433123 338__ $$aonline resource$$bcr$$2rdacarrier
001433123 347__ $$atext file
001433123 347__ $$bPDF
001433123 500__ $$aIncludes index.
001433123 5050_ $$aHuman Cancer- Epidemiology, Hallmarks, and Defense Strategies -- Cancer Treatment Modalities Systemic and Loco regional Approaches: Challenges and Opportunities of multidisciplinary approaches -- Cancer Radiotherapy: General Considerations and Human Radiobiology -- Radionuclide Cancer Therapy- Unsealed Alpha, Beta and Gamma Emitters -- Locoregional Therapy -- Cancer Interventions with and without Radionuclides -- Radiation Dosimetry Considerations of Locoregional Radionuclide Cancer Therapy -- Voxel-based Targeted Radionuclide Therapy Dosimetry -- Locoregional Unsealed Radionuclide Cancer Therapy -- Experimental Findings -- Animal Cancer Therapy Models -- Ready Translation to Humans -- An Overview of Regulations of Radiopharmaceuticals -- Locoregional Radionuclide Cancer Therapy (LRCT) Using Sealed & Unsealed Radionuclides.
001433123 506__ $$aAccess limited to authorized users.
001433123 520__ $$aThis book reviews locoregional radionuclide cancer therapies (LRCT). Proving an increasingly viable alternative to radiotherapy, radionuclide therapy includes a diversity of choices of well characterized biochemical and physiologic target molecules. The delivery and retention of radionuclides may be monitored by advanced imaging for exact tissue localization and for real-time dosimetry to enable personalized precision medicine. Radiopharmaceuticals in human cancer therapies are typically delivered in systemic routes but can also be designed for locoregional routes to harness pharmacokinetic advantages of higher payload and lower systemic toxicities. This book explores the latest advancements and clinical considerations of the locoregional approach. Throughout the chapters, the clinical and scientific bases of cancer treatment and the locoregional use of radionculides are explored. Mathematical models of radiation dosimetry of locoregional radionculdies on tissues are studied using common models for multiple commercially available radionuclides. Rodent and canine tumor models of LRCT are compared for selected radionuclides and radiopharmaceuticals. The practical aspects of radiopharmaceuticals production, marketing, transport, as well as radiation protection are reviewed. Finally, the combination of LRCT with immunotherapy and other cancer therapies and prospective future use of LRCT are discussed. This is a guide for practicing nuclear physicians, interventional radiologists, radiation oncologists, radiation scientists, veterinarians and oncologists to expand their knowledge base and to prepare for designing locoregional radionuclide cancer therapies in animals and in humans.
001433123 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed February 25, 2021).
001433123 650_0 $$aRadiopharmaceuticals.
001433123 650_0 $$aCancer$$xRadiotherapy.
001433123 650_0 $$aNuclear medicine.
001433123 650_0 $$aRadiology.
001433123 650_0 $$aInternal medicine.
001433123 650_6 $$aRadiopharmaceutiques.
001433123 650_6 $$aCancer$$xRadiothérapie.
001433123 650_6 $$aMédecine nucléaire.
001433123 650_6 $$aRadiologie.
001433123 650_6 $$aMédecine interne.
001433123 655_0 $$aElectronic books.
001433123 7001_ $$aWong, Franklin C. L.,$$eeditor.
001433123 77608 $$iPrint version:$$z3030562662
001433123 852__ $$bebk
001433123 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-56267-0$$zOnline Access$$91397441.1
001433123 909CO $$ooai:library.usi.edu:1433123$$pGLOBAL_SET
001433123 980__ $$aBIB
001433123 980__ $$aEBOOK
001433123 982__ $$aEbook
001433123 983__ $$aOnline
001433123 994__ $$a92$$bISE