Mechanism of functional expression of F1-ATPase / Masahiro Kinoshita.
Kinoshita, Masahiro, author.
2021
QP609.A3
Available Online

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Title Mechanism of functional expression of F1-ATPase / Masahiro Kinoshita.
Author Kinoshita, Masahiro, author.
ISBN 9789813362321 (electronic bk.)
9813362324 (electronic bk.)
9813362316
9789813362314
DOI https://doi.org/10.1007/978-981-33-6232-1
Published Singapore : Springer, [2021]
Language English
Description 1 online resource (xi, 79 pages) : illustrations (some color)
Item Number 10.1007/978-981-33-6232-1 doi
Call Number QP609.A3
Dewey Decimal Classification 572/.793
Summary This book presents a new view of the mechanism of functional expression of ATP-driven motors (proteins or protein complexes). It is substantially different from the prevailing idea that the motor converts chemical energy to mechanical work. To facilitate understanding, the differences between the new and prevailing views are explained using many illustrations. The book is of interest to those who are not convinced of the notion of chemomechanical coupling. The claims presented are the following: The system, which comprises not only the motor but also water, does no mechanical work during the ATP hydrolysis cycle; a protein is moved or a protein in the complex is rotated by the entropic force generated by water. The highlight of the explanation in the book is that the mechanism of unidirectional rotation of the central shaft in F1-ATPase is discussed in detail on the basis of this new view. The hydration entropy of each [beta] subunit to which a specific chemical compound (ATP, ADP and Pi, Pi, or nothing) is bound, the hydration entropy of the [alpha]3[beta]3 complex, and the dependence of the hydration entropy of F1-ATPase on the orientation of the [gamma] subunit play essential roles.
Bibliography, etc. Note Includes bibliographical references.
Access Note Access limited to authorized users.
Digital File Characteristics text file
PDF
Source of Description Online resource; title from PDF title page (SpringerLink, viewed February 25, 2021).
Series SpringerBriefs in molecular science, 2191-5407
Available in Other Form Mechanism of functional expression of F1-ATPase.
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1. Introduction
2. A New View on Mechanism of Functional Expression of an ATP-Driven Motor
3. Mechanism of Unidirectional Rotation of [gamma]-Subunit in F1-ATPase
4. Concluding Remarks.

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