Mathematical, computational and experimental T cell immunology / Carmen Molina-París, Grant Lythe, editors.
Molina-París, Carmen, editor.; Lythe, Grant, 1966- editor.
2021
QR185.8.T2
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Title
Mathematical, computational and experimental T cell immunology / Carmen Molina-París, Grant Lythe, editors.
ISBN
9783030572044 (electronic bk.)
3030572048 (electronic bk.)
303057203X
9783030572037
DOI
https://doi.org/10.1007/978-3-030-57204-4
Publication Details
Cham : Springer, 2021.
Language
English
Description
1 online resource
Item Number
10.1007/978-3-030-57204-4 doi
Call Number
QR185.8.T2
Dewey Decimal Classification
571.9/66
Summary
The purpose of this book is to present current mathematical and computational models that are used to describe and characterise the immunology of T cells. The reader will be exposed to a variety of tools/methods that go hand-in-hand with the T cell-mediated immunological process that is being modelled. We aim in the proposed book to emphasise the role that mathematical (or computational) modelling has already played in Immunology. Each chapter will provide an example of the contribution of mathematics to T cell immunology under one of the following four headings: i) Generation of hypotheses, ii) Quantification of immunological processes, iii) Definition of observables to measure given an experimental objective, iv) reconciling disparate (or even conflicting) experimental results.
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Molina-París, Carmen, editor.
Lythe, Grant, 1966- editor.
Available in Other Form
Mathematical, computational and experimental T cell immunology.
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Section 1MODELING THE DYNAMICS OF CD4+ T CELLS IN HIV- 1 INFECTION
Modelling the response to Interleukin-7 therapy in HIV-infected patients
Modeling immunopathology during persistent viral infections
Delay in differentiation may suggest division of labour in models for CD8+ T cell differentiation
Inferring differentiation order in adaptive immune responses from population level data
Experimental and mathematical approaches to quantify recirculation kinetics of lymphocytes
The public face and private lives of T cell receptor repertoires
Population dynamics of immune repertoires
Mathematical Modelling of T cell activation
Agent-based model of heterogeneous T cell activation in vitro
CTLA-4 mediated ligand trans-endocytosis: a stochastic model
Automated gating and dimension reduction of high-dimensional cytometry data
Index.

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