001433365 000__ 05327cam\a2200613\a\4500 001433365 001__ 1433365 001433365 003__ OCoLC 001433365 005__ 20230309003602.0 001433365 006__ m\\\\\o\\d\\\\\\\\ 001433365 007__ cr\cn\nnnunnun 001433365 008__ 210108s2021\\\\sz\\\\\\o\\\\\001\0\eng\d 001433365 019__ $$a1231607876$$a1238201836$$a1241066706$$a1256670691 001433365 020__ $$a9783030552732$$q(electronic bk.) 001433365 020__ $$a303055273X$$q(electronic bk.) 001433365 020__ $$z3030552721 001433365 020__ $$z9783030552725 001433365 0247_ $$a10.1007/978-3-030-55273-2$$2doi 001433365 035__ $$aSP(OCoLC)1229899108 001433365 040__ $$aYDX$$beng$$epn$$cYDX$$dGW5XE$$dDCT$$dEBLCP$$dOCLCO$$dDKU$$dBDX$$dOCLCF$$dN$T$$dUKAHL$$dOCLCQ$$dOCLCO$$dCOM$$dOCLCQ 001433365 049__ $$aISEA 001433365 050_4 $$aRC122.B4 001433365 08204 $$a616.5/45$$223 001433365 24500 $$aNeuro-Behçet's disease :$$bpathogenesis, clinical aspects, treatment /$$cErdem Tüzün, Murat Kürtüncü, editors. 001433365 250__ $$a1st ed. 001433365 260__ $$aCham :$$bSpringer,$$c2021. 001433365 300__ $$a1 online resource 001433365 336__ $$atext$$btxt$$2rdacontent 001433365 337__ $$acomputer$$bc$$2rdamedia 001433365 338__ $$aonline resource$$bcr$$2rdacarrier 001433365 347__ $$atext file 001433365 347__ $$bPDF 001433365 500__ $$aIncludes index. 001433365 5050_ $$aIntro -- Preface -- Contents -- Neuro-Behçet's Disease: Epidemiology and Genetics -- Introduction -- Epidemiology -- Prevalence of Neuro-Behçet's Disease -- Age -- Gender -- Genetic Factors -- Familial Aggregation -- HLA-B51 -- Other MHC Class I Genes -- Non-MHC Complex Genes -- Genome-Wide Association Studies -- Il-10 -- IL23R-IL12RB2 -- IL12A -- ERAP1 -- STAT4 -- TNFAIP3 -- CCR1-CCR3 -- KLR -- GIMAP -- FUT2 -- CPLX-1 -- Other Polymorphism Studies -- Rare Non-synonymous Variants -- Epigenetic Studies -- Conclusion -- References -- Immunology of Neuro-Behcet's Disease (NBD) 001433365 5058_ $$aImmune Response in the CSF -- Cellularity of CSF -- Immune Mediators as Indications of Activity in CSF -- Oligoclonal Bands (OCB) -- Other Markers in the CSF -- Cytokines -- Candidate Antigens of Possible Autoimmune Response in NBD -- Heat Shock Protein (HSP) and Related Responses -- Neuronal and Other Proteins -- Cellular Immune Response in NBD -- Other Mechanisms in BD -- Inflammation, Coagulation, and Fibrinolytic Pathway Abnormalities -- Severity and Gender -- Conclusions -- References -- Autoantibodies in Neuro-Behçet Disease -- References -- Animal Models of Behçet's Disease -- Introduction 001433365 5058_ $$aInfection-Induced Models -- Herpes Simplex Virus-Induced Model -- Streptococcal Infection Model -- Genetic Models -- Immunological Models -- Heat Shock Protein Model -- Anti-neuronal Antibody Model -- Tropomyosin Model -- Retinal S-Antigen Model -- Environmental Models -- Therapeutic Studies of BD Animal Models -- Conclusion -- References -- Pathology -- Parenchymal NBD -- Histological Findings -- Non-parenchymal NBD -- Peripheral Nervous System Involvement -- References -- Behçet's Disease: Clinical Features -- Introduction -- Clinical Features -- Mucocutaneous Involvement 001433365 5058_ $$aRecurrent Aphthous Ulcers -- Genital Ulcers -- Cutaneous Lesions -- Pathergy Reaction -- Eye Involvement -- Musculoskeletal Disease -- Vascular Involvement -- Gastrointestinal Involvement -- Other Clinical Findings -- References -- Neuro-Behçet Syndrome: Differential Diagnosis -- Differentiation of p-NBS from Other Mimickers by MRI Patterns -- Differentiation of p-NBS from Other Mimickers by Laboratory Findings -- Differentiation of p-NBS from Other Mimickers by Pathological Findings -- References -- Neuro-Behçet Syndrome: Clinical Features -- Parenchymal NBS -- Neurovascular Involvement 001433365 5058_ $$aCerebral Venous Sinus Thrombosis (CVST) -- Arterial Occlusion and Aneurysm Formation -- Primary Neurological Conditions Other than p-NBS and Neurovascular Involvement -- Regarding Clinical Features, When Should We Suspect NBS? -- References -- The Cerebrospinal Fluid Presentations of Neuro-Behçet Disease -- CSF Cells -- CSF Protein -- CSF Glucose -- Oligoclonal Bands -- Interleukin-6 -- Other CSF Studies -- References -- Imaging of Neuro-Behçet's Disease -- Introduction -- Neuroimaging Tools in NBD 001433365 506__ $$aAccess limited to authorized users. 001433365 520__ $$aThis contributed volume provides a complete overview of Neuro-Behcets disease (NBD), one of the most serious manifestations of Behcets disease. It serves as a comprehensive and critical review of the current scientific literature regarding NBD, covering the epidemiology, pathology, prognosis, and treatment of the disease. This book is an essential resource for both researchers and physicians working on neurology, rheumatology, and internal medicine fields. 001433365 588__ $$aDescription based on print version record. 001433365 650_0 $$aBehçet's disease. 001433365 650_0 $$aNervous system$$xDiseases. 001433365 650_6 $$aSyndrome de Behçet. 001433365 650_6 $$aSystème nerveux$$xMaladies. 001433365 655_0 $$aElectronic books. 001433365 7001_ $$aTüzün, Erdem. 001433365 7001_ $$aKürtüncü, Murat. 001433365 77608 $$iPrint version:$$tNeuro-Behçet's disease.$$dCham : Springer, 2021$$z9783030552732$$w(OCoLC)1160595103 001433365 852__ $$bebk 001433365 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-55273-2$$zOnline Access$$91397441.1 001433365 909CO $$ooai:library.usi.edu:1433365$$pGLOBAL_SET 001433365 980__ $$aBIB 001433365 980__ $$aEBOOK 001433365 982__ $$aEbook 001433365 983__ $$aOnline 001433365 994__ $$a92$$bISE