001433405 000__ 03792cam\a2200613\a\4500 001433405 001__ 1433405 001433405 003__ OCoLC 001433405 005__ 20230309003604.0 001433405 006__ m\\\\\o\\d\\\\\\\\ 001433405 007__ cr\un\nnnunnun 001433405 008__ 210110s2021\\\\sz\\\\\\o\\\\\000\0\eng\d 001433405 019__ $$a1231611441$$a1238201507 001433405 020__ $$a9783030663063$$q(electronic bk.) 001433405 020__ $$a303066306X$$q(electronic bk.) 001433405 020__ $$z3030663051 001433405 020__ $$z9783030663056 001433405 0247_ $$a10.1007/978-3-030-66306-3$$2doi 001433405 035__ $$aSP(OCoLC)1229972987 001433405 040__ $$aYDX$$beng$$epn$$cYDX$$dSFB$$dOCLCO$$dGW5XE$$dOCLCO$$dDCT$$dEBLCP$$dOCLCF$$dUKAHL$$dOCLCQ$$dOCLCO$$dCOM$$dN$T$$dOCLCQ 001433405 049__ $$aISEA 001433405 050_4 $$aRL120.B66 001433405 08204 $$a615.7/78$$223 001433405 08204 $$a615$$223 001433405 24500 $$aBotulinum toxin therapy /$$cScott M. Whitcup, Mark Hallett, editors. 001433405 260__ $$aCham :$$bSpringer,$$c2021. 001433405 300__ $$a1 online resource 001433405 336__ $$atext$$btxt$$2rdacontent 001433405 337__ $$acomputer$$bc$$2rdamedia 001433405 338__ $$aonline resource$$bcr$$2rdacarrier 001433405 347__ $$atext file 001433405 347__ $$bPDF 001433405 4901_ $$aHandbook of experimental pharmacology ;$$vv. 263 001433405 5050_ $$aPart 1. Basic Science -- The History of Botulinum Toxins in Medicine: A Thousand Year Journey -- The History of Botulinum Toxins in Medicine: A Thousand Year Journey -- Botulinum Neurotoxins: Mechanism of Action -- Manufacturing and Clinical Formulations of Botulinum Neurotoxins -- Novel Native and Engineered Botulinum Neurotoxins -- Part 2. Clinical Practice -- Clinical Pharmacology of Botulinum Toxin Drugs -- The Use of Botulinum Toxin for Treatment of the Dystonias -- The Use of Botulinum Toxin for Treatment of Spasticity -- Use of Botulinum Toxin in Ophthalmology -- Hyperhidrosis and Aesthetics -- Use of Botulinum Toxin in Genitourinary System -- Gastrointestinal Uses of Botulinum Toxin -- The Use of Botulinum Toxin in the Management of Headache Disorders -- Botulinum Toxin and Pain -- The Use of Botulinum Toxin for Treatment of Depression. 001433405 506__ $$aAccess limited to authorized users. 001433405 520__ $$aIn a rapidly progressing field, Botulinum Toxin Therapy provides both clinicians and basic researchers with the latest science on the structure and function of botulinum toxins and the use of these toxins to treat a wide variety of diseases. Part 1 of the book reviews the basic science of botulinum toxins including advances in our understanding of the molecular structure and mechanism of action of botulinum toxins. This section also discusses the manufacturing and formulation of botulinum toxins for clinical use and the development of novel therapeutic toxins for the future. Part 2 reviews the use of botulinum toxins in clinical practice. It discusses the clinical pharmacology of botulinum toxin drugs and their use in a wide variety of clinical conditions including headache, spasticity, pain, disorders of the genitourinary and gastrointestinal tract, strabismus, and medical aesthetics. 001433405 650_0 $$aBotulinum toxin$$xTherapeutic use. 001433405 650_0 $$aPharmacology. 001433405 650_0 $$aPsychopharmacology. 001433405 650_0 $$aNeurosciences. 001433405 650_6 $$aToxines botuliniques$$xEmploi en thérapeutique. 001433405 650_6 $$aPharmacologie. 001433405 650_6 $$aPsychopharmacologie. 001433405 650_6 $$aNeurosciences. 001433405 655_0 $$aElectronic books. 001433405 7001_ $$aWhitcup, Scott M. 001433405 7001_ $$aHallett, Mark. 001433405 77608 $$iPrint version:$$tBotulinum toxin therapy.$$dCham : Springer, 2021$$z3030663051$$z9783030663056$$w(OCoLC)1223068486 001433405 830_0 $$aHandbook of experimental pharmacology ;$$vv. 263. 001433405 852__ $$bebk 001433405 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-66306-3$$zOnline Access$$91397441.1 001433405 909CO $$ooai:library.usi.edu:1433405$$pGLOBAL_SET 001433405 980__ $$aBIB 001433405 980__ $$aEBOOK 001433405 982__ $$aEbook 001433405 983__ $$aOnline 001433405 994__ $$a92$$bISE