001433534 000__ 03858cam\a2200565\i\4500 001433534 001__ 1433534 001433534 003__ OCoLC 001433534 005__ 20230309003611.0 001433534 006__ m\\\\\o\\d\\\\\\\\ 001433534 007__ cr\cn\nnnunnun 001433534 008__ 210123s2021\\\\sz\\\\\\o\\\\\001\0\eng\d 001433534 019__ $$a1225066636$$a1237465079$$a1238203517$$a1246357431 001433534 020__ $$a9783030546304$$q(electronic bk.) 001433534 020__ $$a3030546306$$q(electronic bk.) 001433534 020__ $$z9783030546298 001433534 020__ $$z3030546292 001433534 0247_ $$a10.1007/978-3-030-54630-4$$2doi 001433534 035__ $$aSP(OCoLC)1232280516 001433534 040__ $$aEBLCP$$beng$$erda$$epn$$cEBLCP$$dGW5XE$$dYDX$$dOCLCO$$dSFB$$dN$T$$dDCT$$dOCLCF$$dUKAHL$$dOCLCQ$$dOCLCO$$dOCLCQ 001433534 049__ $$aISEA 001433534 050_4 $$aQR183.5 001433534 08204 $$a616.07/98$$223 001433534 24500 $$aIntroduction to antibody engineering /$$cFlorian Rüker, Gordana Wozniak-Knopp, editors. 001433534 264_1 $$aCham :$$bSpringer,$$c[2021] 001433534 300__ $$a1 online resource (388 pages) 001433534 336__ $$atext$$btxt$$2rdacontent 001433534 337__ $$acomputer$$bc$$2rdamedia 001433534 338__ $$aonline resource$$bcr$$2rdacarrier 001433534 347__ $$atext file 001433534 347__ $$bPDF 001433534 4901_ $$aLearning materials in biosciences 001433534 500__ $$aIncludes index. 001433534 5050_ $$aChapter 1. Introduction by the editors -- Chapter 2. Antibodies A History of their Discovery and Properties -- Chapter 3. Monoclonal Antibodies and Hybridomas -- Chapter 4. Antibody Display Systems -- Chapter 5. Transgenic Animals for the Generation of Human Antibodies -- Chapter 6. Applications of Antibodies in Therapy, Diagnosis & Science -- Chapter 7. Bispecific antibodies -- Chapter 8. Antibody-Drug Conjugates -- Chapter 9. Alternative Binding Scaffolds multipurpose binders for applications in basic research and therapy -- Chapter 10: Chimeric antigen receptor (CAR) redirected T cells -- Chapter 11. Improvement of Key Characteristics of Antibodies -- Chapter 12. Engineering therapeutic antibodies for development -- Chapter 13. Eukaryotic expression systems for upstream pro-cessing of monoclonal antibodies -- Chapter 14. Antibody Validation. 001433534 506__ $$aAccess limited to authorized users. 001433534 520__ $$aThis highly readable textbook serves as a concise and engaging primer to the emerging field of antibody engineering and its various applications. It introduces readers to the basic science and molecular structure of antibodies, and explores how to characterize and engineer them. Readers will find an overview of the latest methods in antibody identification, improvement and biochemical engineering. Furthermore, alternative antibody formats and bispecific antibodies are discussed. The books content is based on lectures for the specializations Protein Engineering, Medical Biotechnology within the Masters curriculum in Biotechnology. The lectures have been held at the University of Natural Resources and Life Sciences, Vienna, in cooperation with the Medical University of Vienna, since 2012 and are continuously adapted to reflect the latest developments in the field. The book addresses Masters and PhD students in biotechnology, molecular biology and immunology, and all those who are interested in antibody engineering. 001433534 588__ $$aDescription based on print version record. 001433534 650_0 $$aImmunotechnology. 001433534 650_0 $$aImmunoglobulins. 001433534 650_6 $$aImmunotechnologie. 001433534 655_0 $$aElectronic books. 001433534 7001_ $$aRüker, Florian,$$eeditor. 001433534 7001_ $$aWozniak-Knopp, Gordana,$$eeditor. 001433534 77608 $$iPrint version:$$aRüker, Florian$$tIntroduction to Antibody Engineering$$dCham : Springer International Publishing AG,c2020$$z9783030546298 001433534 830_0 $$aLearning materials in biosciences. 001433534 852__ $$bebk 001433534 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-54630-4$$zOnline Access$$91397441.1 001433534 909CO $$ooai:library.usi.edu:1433534$$pGLOBAL_SET 001433534 980__ $$aBIB 001433534 980__ $$aEBOOK 001433534 982__ $$aEbook 001433534 983__ $$aOnline 001433534 994__ $$a92$$bISE