Collagen biografts for tunable drug delivery / Rucha Joshi.
Joshi, Rucha (Rucha Vinay), author.
2021
R857.M3
Available Online

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Title Collagen biografts for tunable drug delivery / Rucha Joshi.
Author Joshi, Rucha (Rucha Vinay), author.
ISBN 9783030638177 (electronic bk.)
3030638170 (electronic bk.)
3030638162
9783030638160
DOI https://doi.org/10.1007/978-3-030-63817-7
Published Cham, Switzerland : Springer, [2021]
Language English
Description 1 online resource
Item Number 10.1007/978-3-030-63817-7 doi
Call Number R857.M3
Dewey Decimal Classification 610.28/4
Summary This book reviews collagen-based biomaterials that have been applied broadly to tissue engineering and local drug delivery applications and lays out a landscape for developing a multifunctional biograft material from collagen polymers. The book also discusses current shortcomings in collagen based drug delivery opportunities, including poor mechanical properties, rapid proteolytic degradation, and cursory control over physical properties and molecular release profiles. Finally, a review of application of the collagen biograft materials for promoting neovascularization and tissue regeneration is presented, using examples of established in-vivo chicken egg chorioallantoic membrane (CAM) model. Use of heparin for affinity-based vascular endothelial growth factor (VEGF) retention in collagen constructs is also discussed for promoting neovascularization. Reviews state-of-the-art strategies for drug incorporation and retention in collagen ; Covers collagen based material applications for improving vascularization and tissue regeneration; Illustrates how to tailor collagen architecture for soft tissue engineering and controlled drug delivery.
Bibliography, etc. Note Includes bibliographical references and index.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed March 11, 2021).
Series SpringerBriefs in applied sciences and technology.
Available in Other Form Collagen biografts for tunable drug delivery.
Linked Resources Online Access
Record Appears in Online Resources > Ebooks
All Resources
Introduction to drug delivery
From in vivo synthesis to in vitro drug delivery device formation
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Application of collagen fibril biografts for enhancing local vascularization in an in-vivo chick chorioallantoic membrane (CAM) model.

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