001433647 000__ 03891cam\a2200625\i\4500 001433647 001__ 1433647 001433647 003__ OCoLC 001433647 005__ 20230309003646.0 001433647 006__ m\\\\\o\\d\\\\\\\\ 001433647 007__ cr\un\nnnunnun 001433647 008__ 210202s2021\\\\sz\\\\\\ob\\\\001\0\eng\d 001433647 019__ $$a1236263939$$a1239684756 001433647 020__ $$a9783030638177$$q(electronic bk.) 001433647 020__ $$a3030638170$$q(electronic bk.) 001433647 020__ $$z3030638162 001433647 020__ $$z9783030638160 001433647 0247_ $$a10.1007/978-3-030-63817-7$$2doi 001433647 035__ $$aSP(OCoLC)1235871802 001433647 040__ $$aYDX$$beng$$erda$$epn$$cYDX$$dEBLCP$$dUKBTH$$dOCLCF$$dGW5XE$$dUKAHL$$dOCL$$dOCLCO$$dOCLCQ$$dOCLCO$$dCOM$$dOCLCQ 001433647 049__ $$aISEA 001433647 050_4 $$aR857.M3 001433647 050_4 $$aQP552.C6 001433647 08204 $$a610.28/4$$223 001433647 1001_ $$aJoshi, Rucha$$q(Rucha Vinay),$$eauthor. 001433647 24510 $$aCollagen biografts for tunable drug delivery /$$cRucha Joshi. 001433647 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2021] 001433647 300__ $$a1 online resource 001433647 336__ $$atext$$btxt$$2rdacontent 001433647 337__ $$acomputer$$bc$$2rdamedia 001433647 338__ $$aonline resource$$bcr$$2rdacarrier 001433647 4901_ $$aSpringerBriefs in applied sciences and technology 001433647 504__ $$aIncludes bibliographical references and index. 001433647 5050_ $$aIntroduction to drug delivery -- From in vivo synthesis to in vitro drug delivery device formation -- Creating tunable collagen matrices : an approach inspired by in-vivo collagen synthesis and self-assembly -- Collagen biografts for chronic wound healing -- Application of collagen fibril biografts for enhancing local vascularization in an in-vivo chick chorioallantoic membrane (CAM) model. 001433647 506__ $$aAccess limited to authorized users. 001433647 520__ $$aThis book reviews collagen-based biomaterials that have been applied broadly to tissue engineering and local drug delivery applications and lays out a landscape for developing a multifunctional biograft material from collagen polymers. The book also discusses current shortcomings in collagen based drug delivery opportunities, including poor mechanical properties, rapid proteolytic degradation, and cursory control over physical properties and molecular release profiles. Finally, a review of application of the collagen biograft materials for promoting neovascularization and tissue regeneration is presented, using examples of established in-vivo chicken egg chorioallantoic membrane (CAM) model. Use of heparin for affinity-based vascular endothelial growth factor (VEGF) retention in collagen constructs is also discussed for promoting neovascularization. Reviews state-of-the-art strategies for drug incorporation and retention in collagen ; Covers collagen based material applications for improving vascularization and tissue regeneration; Illustrates how to tailor collagen architecture for soft tissue engineering and controlled drug delivery. 001433647 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed March 11, 2021). 001433647 650_0 $$aBiomedical materials$$xTherapeutic use. 001433647 650_0 $$aCollagen$$xTherapeutic use. 001433647 650_0 $$aDrugs$$xControlled release. 001433647 650_0 $$aTissue engineering. 001433647 650_0 $$aBiomedical engineering. 001433647 650_6 $$aBiomatériaux$$xEmploi en thérapeutique. 001433647 650_6 $$aCollagène$$xEmploi en thérapeutique. 001433647 650_6 $$aMédicaments-retard. 001433647 650_6 $$aGénie tissulaire. 001433647 650_6 $$aGénie biomédical. 001433647 655_0 $$aElectronic books. 001433647 77608 $$iPrint version:$$aJoshi, Rucha (Rucha Vinay).$$tCollagen biografts for tunable drug delivery.$$dCham, Switzerland : Springer, [2021]$$z3030638162$$z9783030638160$$w(OCoLC)1201386884 001433647 830_0 $$aSpringerBriefs in applied sciences and technology. 001433647 852__ $$bebk 001433647 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-63817-7$$zOnline Access$$91397441.1 001433647 909CO $$ooai:library.usi.edu:1433647$$pGLOBAL_SET 001433647 980__ $$aBIB 001433647 980__ $$aEBOOK 001433647 982__ $$aEbook 001433647 983__ $$aOnline 001433647 994__ $$a92$$bISE