001434627 000__ 04730cam\a2200541\i\4500 001434627 001__ 1434627 001434627 003__ OCoLC 001434627 005__ 20230309003810.0 001434627 006__ m\\\\\o\\d\\\\\\\\ 001434627 007__ cr\un\nnnunnun 001434627 008__ 210301s2021\\\\sz\a\\\\o\\\\\000\0\eng\d 001434627 019__ $$a1241442535$$a1241451202$$a1244120900$$a1244636359 001434627 020__ $$a9783030678142$$q(electronic bk.) 001434627 020__ $$a3030678148$$q(electronic bk.) 001434627 020__ $$z9783030678135$$q(print) 001434627 020__ $$z303067813X$$q(print) 001434627 0247_ $$a10.1007/978-3-030-67814-2$$2doi 001434627 035__ $$aSP(OCoLC)1241065847 001434627 040__ $$aDKU$$beng$$epn$$cDKU$$dOCLCO$$dBDX$$dOCLCQ$$dGW5XE$$dYDX$$dEBLCP$$dOCLCO$$dDCT$$dOCLCF$$dUKAHL$$dOCLCQ$$dOCLCO$$dCOM$$dOCLCQ 001434627 049__ $$aISEA 001434627 050_4 $$aQP551 001434627 08204 $$a572/.6$$223 001434627 24500 $$aProtein reviews.$$nVolume 21 /$$cM. Zouhair Atassi, editor. 001434627 264_1 $$aCham :$$bSpringer,$$c2021. 001434627 300__ $$a1 online resource (vii, 213 pages) :$$billustration 001434627 336__ $$atext$$btxt$$2rdacontent 001434627 337__ $$acomputer$$bc$$2rdamedia 001434627 338__ $$aonline resource$$bcr$$2rdacarrier 001434627 347__ $$atext file 001434627 347__ $$bPDF 001434627 4901_ $$aProtein reviews,$$x2520-1891 ;$$vv. 21 001434627 5050_ $$aChapter 1. The Degron Architecture of Squalene Monooxygenase and How Specific Lipids Calibrate Levels of This Key Cholesterol Synthesis Enzyme -- Chapter 2. Heteromeric Solute Carriers: Function, Structure, Pathology and Pharmacology -- Chapter 3. Collagen IV Exploits a Cl- Step Gradient for Scaffold Assembly -- Chapter 4. Roles of Slit Ligands and Their Roundabout (Robo) Family of Receptors in Bone Remodeling -- Chapter 5. Characterization of C. elegans Chondroitin Proteoglycans and Their Large Functional and Structural Heterogeneity; Evolutionary Aspects on Structural Differences Between Humans and the Nematode -- Chapter 6. Structural Basis of a Conventional Recognition Mode of IGHV1-69 Rheumatoid Factors -- Chapter 7. Regulated Alternative Translocation: A Mechanism Regulating Transmembrane Proteins Through Topological Inversion -- Chapter 8. Interleukin-36: Structure, Signaling and Function. 001434627 506__ $$aAccess limited to authorized users. 001434627 520__ $$aThe Protein Reviews series serves as a publication vehicle for reviews that focus on crucial contemporary and vital aspects of protein structure, function, evolution and genetics. Volumes are published online first, prior to publication in a printed book. Chapters are selected according to their importance to the understanding of biological systems, relevance to the unravelling of issues associated with health and disease, or impact on scientific or technological advances and developments. Volume 21 presents eight review chapters authored by experts in the related fields. The first chapter covers the enzyme squalene monooxygenase and lipid levels and its relevance in health and disease. Chapter two presents a systematic analysis of the structural and functional aspects of heteromeric solute carriers. The third chapter provides a review of the role of CI- in type IV collagen assembly, function, and disease, including future directions for studies.^This is followed by a summary in chapter four about the recent progress on defining the roles of the Slit-Robo signaling in bone metabolism and the possible roles of the interaction between Robo and neural epidermal growth factor-like proteins. Chapter five discusses recent data about the evolutionary aspects on structural differences between humans and the nematode in relation to previous knowledge of core proteins and GAG-attachment sites in Chn and CS proteoglycans of C.elegans and humans. The sixth chapter summarizes the immunochemical character of the IGHV1-69-derived RFs and the recognition mechanism of the IGHV1-69-derived RFs. Chapter seven covers regulated alternative translocation and its role as an emerging mechanism to regulate transmembrane proteins. Finally, chapter eight reviews current progress on IL-36 protein and biology and novel investigative tools.^This volume is intended for research scientists, clinicians, physicians and graduate students in the fields of biochemistry, cell biology, molecular biology, immunology and genetics. 001434627 650_0 $$aProteins. 001434627 650_6 $$aProtéines. 001434627 655_0 $$aElectronic books. 001434627 7001_ $$aAtassi, M. Zouhair,$$eeditor. 001434627 77608 $$iPrint version: $$z9783030678135 001434627 77608 $$iPrint version: $$z9783030678159 001434627 77608 $$iPrint version: $$z9783030678166 001434627 830_0 $$aProtein reviews ;$$vv. 21.$$x2520-1891 001434627 852__ $$bebk 001434627 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-67814-2$$zOnline Access$$91397441.1 001434627 909CO $$ooai:library.usi.edu:1434627$$pGLOBAL_SET 001434627 980__ $$aBIB 001434627 980__ $$aEBOOK 001434627 982__ $$aEbook 001434627 983__ $$aOnline 001434627 994__ $$a92$$bISE