001434829 000__ 04633cam\a2200517\a\4500 001434829 001__ 1434829 001434829 003__ OCoLC 001434829 005__ 20230309003821.0 001434829 006__ m\\\\\o\\d\\\\\\\\ 001434829 007__ cr\un\nnnunnun 001434829 008__ 210313s2021\\\\si\\\\\\o\\\\\000\0\eng\d 001434829 019__ $$a1241442087$$a1241665221 001434829 020__ $$a9789813360136$$q(electronic bk.) 001434829 020__ $$a9813360135$$q(electronic bk.) 001434829 020__ $$z9813360127 001434829 020__ $$z9789813360129 001434829 0247_ $$a10.1007/978-981-33-6013-6$$2doi 001434829 035__ $$aSP(OCoLC)1241451196 001434829 040__ $$aEBLCP$$beng$$epn$$cEBLCP$$dYDX$$dGW5XE$$dOCLCO$$dEBLCP$$dUKAHL$$dDKU$$dOCLCO$$dOCLCQ$$dOCLCO$$dCOM$$dOCLCQ$$dCASUM 001434829 049__ $$aISEA 001434829 050_4 $$aRC280.G5 001434829 08204 $$a616.99/4606$$223 001434829 24500 $$aMolecular diagnosis and targeting for gynecologic malignancy /$$cSeiji Isonishi, Yoshihiro Kikuch, editors. 001434829 260__ $$aSingapore :$$bSpringer,$$c2021. 001434829 300__ $$a1 online resource (171 pages) 001434829 336__ $$atext$$btxt$$2rdacontent 001434829 337__ $$acomputer$$bc$$2rdamedia 001434829 338__ $$aonline resource$$bcr$$2rdacarrier 001434829 4901_ $$aCurrent Human Cell Research and Applications 001434829 5050_ $$a1 Cancer Stem Cells in gynecologic cancer -- 2 Patient-derived xenograft models in gynaecological malignancies -- 3 Cancer genomic profiling of gynecological malignancies by Todai OncoPanel, a twin DNA and RNA panel -- 4 Investigating the molecular carcinogenesis of ovarian high-grade serous cancer -- 5 The role of G protein-coupled receptor signaling in gynecologic malignancy -- 6 Tailor-made therapy according genetic alteration in epithelial ovarian cancers -- 7 Signaling and drug resistance -- 8 Molecular analysis in endometrial carcinoma -- 9 Molecular Landscape in Ovarian Clear Cell Carcinoma -- 10 Molecular pathology and clinicopathological significance of endometrial carcinoma -- 11 Novel approach for therapeutics of cervical cancer based on HPV-associated carcinogenesis at the cervix -- 12 Hereditary gynecological malignancy and molecular features. 001434829 506__ $$aAccess limited to authorized users. 001434829 520__ $$aThis book summarizes the important developments in the field of cancer research, specifically uterine cervical/endometrial cancer and ovarian cancer. It highlights the recent advances in gynecologic cancer, such as next generation models of genetically engineered animal models or cancer cell lines, focusing on their significance for advancing our understanding of gynecologic cancer biology, prevention and treatment, and drug response and resistance. Cancer research in the area of gynecologic tumors has undergone an enormous transformation over the past decade, with a greater understanding of tumor biology, elucidation of novel targets for therapeutic intervention, and better recognition of genetic predisposition syndromes. At the same time, the recent advances in basic cancer research have provided key insights into all aspects of gynecologic cancer biology, including developmental pathways and the impact of lineage plasticity, understanding metastatic progression, uncovering the roles of the tumor microenvironment, exploring tumor evolution, and discovering new therapeutic approaches and mechanisms of drug sensitivity and adaptive response. Molecular Diagnosis and Targeting for Gynecologic Malignancy appeals to investigators, clinicians, residents and postdocs who are curious about new research on gynecologic malignancies. It not only presents basic and translational research, but also explores the generalizability of the evidence covering the interface between basic and clinical science. Furthermore, a number of the topics offer the basis for new ideas that have the potential to advance into the gynecologic malignancies. This book provides readers with state-of-the-art information that will help improve the lives of patients with these challenging diseases. 001434829 588__ $$aDescription based on print version record. 001434829 650_0 $$aGenerative organs, Female$$xCancer$$xMolecular diagnosis. 001434829 650_6 $$aOrganes génitaux femelles$$xCancer$$xDiagnostic moléculaire. 001434829 655_0 $$aElectronic books. 001434829 7001_ $$aIsonishi, Seiji. 001434829 7001_ $$aKikuchi, Yoshihiro. 001434829 77608 $$iPrint version:$$aIsonishi, Seiji.$$tMolecular Diagnosis and Targeting for Gynecologic Malignancy.$$dSingapore : Springer Singapore Pte. Limited, ©2021$$z9789813360129 001434829 830_0 $$aCurrent human cell research and applications. 001434829 852__ $$bebk 001434829 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-33-6013-6$$zOnline Access$$91397441.1 001434829 909CO $$ooai:library.usi.edu:1434829$$pGLOBAL_SET 001434829 980__ $$aBIB 001434829 980__ $$aEBOOK 001434829 982__ $$aEbook 001434829 983__ $$aOnline 001434829 994__ $$a92$$bISE