001434943 000__ 05521cam\a2200577\a\4500 001434943 001__ 1434943 001434943 003__ OCoLC 001434943 005__ 20230309003827.0 001434943 006__ m\\\\\o\\d\\\\\\\\ 001434943 007__ cr\un\nnnunnun 001434943 008__ 210319s2021\\\\sz\\\\\\o\\\\\001\0\eng\d 001434943 019__ $$a1243554159$$a1244118323$$a1244630481$$a1249944011$$a1253415066 001434943 020__ $$a9783030550356$$q(electronic bk.) 001434943 020__ $$a3030550354$$q(electronic bk.) 001434943 020__ $$a9783030550363$$q(print) 001434943 020__ $$a3030550362 001434943 020__ $$z3030550346 001434943 020__ $$z9783030550349 001434943 0247_ $$a10.1007/978-3-030-55035-6$$2doi 001434943 035__ $$aSP(OCoLC)1242406009 001434943 040__ $$aYDX$$beng$$epn$$cYDX$$dGW5XE$$dOCLCO$$dDCT$$dEBLCP$$dOCLCF$$dLEATE$$dVT2$$dLIP$$dOCLCQ$$dOCLCO$$dCOM$$dOCLCQ 001434943 049__ $$aISEA 001434943 050_4 $$aRM301.63 001434943 08204 $$a615.1/9$$223 001434943 24500 $$aReviews on new drug targets in age-related disorders.$$nPart II /$$cPaul C. Guest, editor. 001434943 260__ $$aCham :$$bSpringer,$$c2021. 001434943 300__ $$a1 online resource 001434943 336__ $$atext$$btxt$$2rdacontent 001434943 337__ $$acomputer$$bc$$2rdamedia 001434943 338__ $$aonline resource$$bcr$$2rdacarrier 001434943 347__ $$atext file 001434943 347__ $$bPDF 001434943 4901_ $$aAdvances in experimental medicine and biology, Proteomics, metabolomics, interactomics and systems biology,$$x2730-6216 ;$$v1286 001434943 500__ $$aIncludes index. 001434943 5050_ $$aNew Therapeutic Approaches and Biomarkers for Increased Healthspan -- Targeting Cancer Metabolism and Current Anti-Cancer Drugs -- A Review of Monoclonal Antibody-based Treatments in Non-small Cell Lung Cancer -- Parkinson's Disease and Impairment in Mitochondrial Metabolism: A Pathognomic Signature -- Targeted Treatment of Age-related Fibromyalgia with Supplemental Coenzyme Q10 -- Immunoregulatory Effects of Tolerogenic Probiotics in Multiple Sclerosis -- Multifaceted Roles of Long Non-coding RNAs in Head and Neck Cancer -- A Systematic Review on the Genotoxic Effects of Selective Serotonin Reuptake Inhibitors -- Towards a New Era for the Management of Circulating Tumor Cells -- Telomerase: A target for Therapeutic Effects of Curcumin in Cancer -- Aspirin as a Potential Geroprotector: Experimental Data and Clinical Evidence -- Targeting Stem Cells in Chronic Inflammatory Diseases -- Therapeutic Strategies and Nano-drug Delivery Applications in Management of Aging Alzheimer's Disease -- Psychometric Evaluation of Stress in 17,414 Critical Care Unit Nurses: Effects of Age, Gender and Working Conditions -- Targeting Age-related Neurodegenerative Diseases by AAV Mediated Gene Therapy -- Is Adipose Tissue the Fountain of Youth? The impact of Adipose Atem Cell Aging on Metabolic Homeostasis, Longevity and Cell-Based Therapies -- Proteomics for Target Identification in Psychiatric and Neurodegenerative Disorders -- Index. 001434943 506__ $$aAccess limited to authorized users. 001434943 520__ $$aAging is an inevitable part of life, and is becoming a worldwide social, economic and health problem due to the fact that an increasing proportion of individuals in the advanced age category have a higher probability of developing age-related disorders. New therapeutic approaches are still in need to decrease or slow the effects of such diseases in this aging society. Advances in 'omic technologies such as genomics, transcriptomics, proteomics and metabolomics have significantly advanced our understanding of diseases in multiple medical areas. It is hoped that emerging hits from these analyses might be prioritized for further screening as potential novel drug targets for increasing the human healthspan in line with the lifespan, which will in turn lead to new therapeutic strategies and drug development projects by the pharmaceutical industry. This new book presents a series of reviews describing studies which have resulted in the identification of potential new drug targets for age-related disorders. Much of this information has come from 'omic comparisons of healthy and disease states or from testing the effects of potential new therapeutic approaches. Each chapter will be presented in the context of specific chronic diseases or different therapeutic strategies, providing important information on disease mechanisms related to the aging process. This book will be of interest to researchers in the areas of aging and chronic disease, as well as clinical scientists, physicians, and major drug companies. With contributors from Australia, Brazil, Canada, France, Germany, India, Iran, Iraq, South Africa, South Korea, Thailand, Ukraine, United Kingdom, United States of America, Uruguay and Vietnam, this is a timely follow up to Guest's previous book Reviews on New Drug Targets in Age-Related Disorders. 001434943 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed April 5, 2021). 001434943 650_0 $$aDrug targeting. 001434943 650_6 $$aMédicaments$$xCiblage. 001434943 655_0 $$aElectronic books. 001434943 7001_ $$aGuest, Paul C.,$$eeditor. 001434943 77608 $$iPrint version:$$tReviews on new drug targets in age-related disorders. Part II.$$dCham : Springer, 2021$$z3030550346$$z9783030550349$$w(OCoLC)1160938132 001434943 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1286.$$x2730-6216 001434943 830_0 $$aAdvances in experimental medicine and biology.$$pProteomics, metabolomics, interactomics and systems biology. 001434943 852__ $$bebk 001434943 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-55035-6$$zOnline Access$$91397441.1 001434943 909CO $$ooai:library.usi.edu:1434943$$pGLOBAL_SET 001434943 980__ $$aBIB 001434943 980__ $$aEBOOK 001434943 982__ $$aEbook 001434943 983__ $$aOnline 001434943 994__ $$a92$$bISE