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Table of Contents
Intro
Foreword
Preface
Preface
Contents
1: Physiopathology of Overactive Bladder
1.1 Definitions
1.2 Pathophysiology
1.3 Neurogenic Factors
1.4 Non-neurogenic Factors
1.4.1 Myogenic Factor
1.4.2 Urotheliogenic Factor
1.4.3 Bladder Outlet Obstruction
1.4.4 Bladder Ischemia
1.4.5 Inflammation
1.4.6 Gender
1.4.7 Psychological Factors
References
2: Diagnosis of Overactive Bladder
2.1 The Initial Diagnostic Workup in the Uncomplicated OAB Patient
2.1.1 History
2.1.2 Physical Examination
2.1.3 Urinalysis and Urine Culture
2.1.4 Voiding Diaries and Pad Testing
2.1.5 Symptom Questionnaires and Scores
2.2 The Diagnostic Workup in the Complicated OAB Patient
2.2.1 Cystoscopy
2.2.2 Urinary Tract Ultrasound
2.2.3 Uroflowmetry
2.2.4 Urodynamic Test
References
3: Treatment Options in Patients with Overactive Bladder: Initial and Pharmacological Management
3.1 Introduction
3.2 Initial Management of Overactive Bladder
3.2.1 Lifestyle Modification
3.3 Pharmacological Treatment of Overactive Bladder Symptoms
3.3.1 Antimuscarinics Drugs
3.5.1.3 Cognitive Impairment
3.5.1.4 Associate BOO
3.5.1.5 Frail Older Patients
References
4: Treatment Options in Patients with Overactive Bladder: The Invasive Management
4.1 Introduction
4.2 Botulinum Toxin
4.2.1 Molecular Structure and Mechanism of Action
4.2.2 BoNTA Intradetrusor Injection
4.2.3 BoNTA Efficacy
4.2.4 Adverse Events
4.3 Sacral Neuromodulation (SNM)
4.3.1 Technique
4.3.2 Mechanism of Action
4.3.3 SNM Efficacy
4.3.4 Adverse Events
4.4 Percutaneous Tibial Nerve Stimulation
4.4.1 PTNS Technique and Efficacy
4.5 Major Surgery
4.5.1 Enterocystoplasty
References
5: Bladder Outlet Obstruction and Overactive Bladder in Females
5.1 Lower Urinary Tract Symptoms' Epidemiology
5.2 Bladder Outlet Obstruction Pathophysiology
5.3 OAB Pathophysiology
5.4 Diagnosis
5.4.1 History
5.4.2 Physical Examination
5.4.3 Diagnostic Tools
5.5 Management
5.6 OAB Management
5.7 BOO Management
References
6: Bladder Outlet Obstruction and Overactive Bladder in Males
6.1 Definition
6.2 Epidemiology
6.3 Pathophysology
6.4 Diagnosis
Foreword
Preface
Preface
Contents
1: Physiopathology of Overactive Bladder
1.1 Definitions
1.2 Pathophysiology
1.3 Neurogenic Factors
1.4 Non-neurogenic Factors
1.4.1 Myogenic Factor
1.4.2 Urotheliogenic Factor
1.4.3 Bladder Outlet Obstruction
1.4.4 Bladder Ischemia
1.4.5 Inflammation
1.4.6 Gender
1.4.7 Psychological Factors
References
2: Diagnosis of Overactive Bladder
2.1 The Initial Diagnostic Workup in the Uncomplicated OAB Patient
2.1.1 History
2.1.2 Physical Examination
2.1.3 Urinalysis and Urine Culture
2.1.4 Voiding Diaries and Pad Testing
2.1.5 Symptom Questionnaires and Scores
2.2 The Diagnostic Workup in the Complicated OAB Patient
2.2.1 Cystoscopy
2.2.2 Urinary Tract Ultrasound
2.2.3 Uroflowmetry
2.2.4 Urodynamic Test
References
3: Treatment Options in Patients with Overactive Bladder: Initial and Pharmacological Management
3.1 Introduction
3.2 Initial Management of Overactive Bladder
3.2.1 Lifestyle Modification
3.3 Pharmacological Treatment of Overactive Bladder Symptoms
3.3.1 Antimuscarinics Drugs
3.5.1.3 Cognitive Impairment
3.5.1.4 Associate BOO
3.5.1.5 Frail Older Patients
References
4: Treatment Options in Patients with Overactive Bladder: The Invasive Management
4.1 Introduction
4.2 Botulinum Toxin
4.2.1 Molecular Structure and Mechanism of Action
4.2.2 BoNTA Intradetrusor Injection
4.2.3 BoNTA Efficacy
4.2.4 Adverse Events
4.3 Sacral Neuromodulation (SNM)
4.3.1 Technique
4.3.2 Mechanism of Action
4.3.3 SNM Efficacy
4.3.4 Adverse Events
4.4 Percutaneous Tibial Nerve Stimulation
4.4.1 PTNS Technique and Efficacy
4.5 Major Surgery
4.5.1 Enterocystoplasty
References
5: Bladder Outlet Obstruction and Overactive Bladder in Females
5.1 Lower Urinary Tract Symptoms' Epidemiology
5.2 Bladder Outlet Obstruction Pathophysiology
5.3 OAB Pathophysiology
5.4 Diagnosis
5.4.1 History
5.4.2 Physical Examination
5.4.3 Diagnostic Tools
5.5 Management
5.6 OAB Management
5.7 BOO Management
References
6: Bladder Outlet Obstruction and Overactive Bladder in Males
6.1 Definition
6.2 Epidemiology
6.3 Pathophysology
6.4 Diagnosis