Proteinkinase inhibitors / Stefan Laufer, editor.

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Proteinkinase inhibitors / Stefan Laufer, editor.

9783030681807 (electronic bk.)
3030681807 (electronic bk.)
9783030681814 (print)
3030681815
9783030681821 (print)
3030681823
9783030681791
3030681793

Cham, Switzerland : Springer, 2021.

English

1 online resource (vii, 256 pages).

10.1007/978-3-030-68180-7 doi

QP606.P76

572/.792
615/.798

This book reviews the principles of design and examples of successful implementation of proteinkinase inhibitors (PKI), and offers a comprehensive and authoritative overview of the history and latest developments in the field. Chapters written by experts from industry and academia cover the function, structure and topology of Proteinkinases, molecular modelling, disclose how to achieve high level of selectivity for kinase inhibitors, and exploit kinase inhibitors for cancer treatment. Particular attention is given to Inhibitors of c-Jun N-terminal kinase 3, and to covalent Janus Kinase 3 Inhibitors. A case study on Receptor Tyrosine Kinases EGFR, VEGFR, PDGFR is also presented in this book. Given its breath, this book will appeal to medicinal chemists, students, researchers and professionals alike.

Includes bibliographical references.

Access limited to authorized users.

text file
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Online resource; title from PDF title page (SpringerLink, viewed April 1, 2021).

Topics in medicinal chemistry (Springer (Firm)) ; v. 36.

Print version: 9783030681791

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