001435293 000__ 03831cam\a22006257i\4500 001435293 001__ 1435293 001435293 003__ OCoLC 001435293 005__ 20230309003847.0 001435293 006__ m\\\\\o\\d\\\\\\\\ 001435293 007__ cr\mn\nnnunnun 001435293 008__ 210308s2021\\\\si\a\\\\ob\\\\000\0\eng\d 001435293 019__ $$a1241442762$$a1241445070$$a1244623859$$a1245666421 001435293 020__ $$a9789813347618 001435293 020__ $$a9813347619 001435293 020__ $$z9789813347601 001435293 020__ $$z9813347600 001435293 0247_ $$a10.1007/978-981-33-4761-8$$2doi 001435293 035__ $$aSP(OCoLC)1244117953 001435293 040__ $$aDCT$$beng$$erda$$epn$$cDCT$$dOCLCO$$dEBLCP$$dGW5XE$$dYDX$$dOCLCF$$dORU$$dOCLCO$$dUKAHL$$dOCL$$dCOM$$dOCLCO$$dOCL$$dOCLCQ 001435293 049__ $$aISEA 001435293 050_4 $$aRC157$$b.Q53 2021 001435293 08204 $$a611.01816$$223 001435293 08204 $$a599.935$$223 001435293 1001_ $$aQidwai, Tabish,$$eauthor. 001435293 24510 $$aExploration of host genetic factors associated with malaria /$$cby Tabish Qidwai. 001435293 264_1 $$aSingapore :$$bSpringer,$$c[2021] 001435293 300__ $$a1 online resource (xi, 172 pages) :$$billustrations. 001435293 336__ $$atext$$btxt$$2rdacontent 001435293 336__ $$astill image$$bsti$$2rdacontent 001435293 337__ $$acomputer$$bc$$2rdamedia 001435293 338__ $$aonline resource$$bcr$$2rdacarrier 001435293 347__ $$atext file$$bPDF$$2rda 001435293 504__ $$aIncludes bibliographical references. 001435293 5050_ $$aChapter 1. Human genetics and infectious disease -- Part 1. RBC disorders -- Chapter 2. Sickle cell gene -- Chapter 3. Alpha-Thalassemia -- Chapter 4. Beta-Thalassemia -- Chapter 5. Duffy blood group locus -- Part 2. Metabolic enzymes -- Chapter 6. Pyruvate kinase deficiency -- Chapter 7. Glucose 6-Phosphate dehydrogenase -- Part 3. Host immune response -- Chapter 8. TNF genetic polymorphisms -- Chapter 9. iNos genetic polymorphisms -- Chapter 10. Human complement receptor 1 polymorphisms -- Chapter 11. Interferonalpha receptor-1 (IFNAR1) polymorphisms -- Part 4. Cytoadherence -- Chapter 12. Intercellular adhesion molecule-1 polymorphisms -- Chapter 13. Platelet endothelial cell adhesion molecule-1 (PECAM-1) polymorphisms -- Chapter 14. Vascular cell adhesion molecule-1 (VCAM1) polymorphisms. 001435293 506__ $$aAccess limited to authorized users. 001435293 520__ $$a"This book is aimed to cover the role of genetic polymorphisms in human genes related to RBC disorders, metabolic enzymes, immune response, and cytoadherence in the susceptibility/resistance to malaria caused by Plasmodium falciparum. The chapters provide current information on the balancing trait and the significance of such traits in the malaria resistance. The book covers polymorphisms in the genes of the red blood cells-sickle cell anaemia; glucose-6-phosphate dehydrogenase deficiency and thalassemia that confer protection against malaria. In addition, the book explores selection of genetic variations in the human genome as genetic control mechanism against malaria in endemic regions. It also provides a comprehensive overview of the molecular epidemiology and natural selection of alleles in the genes which are associated with malaria, and presents description of the role of human genetic polymorphisms in malaria disease risk and disease outcome."--$$cProvided by publisher. 001435293 650_0 $$aGenetic polymorphisms. 001435293 650_0 $$aHuman genetics. 001435293 650_0 $$aMalaria$$xImmunological aspects. 001435293 650_0 $$aParasitology. 001435293 650_0 $$aImmunology. 001435293 650_0 $$aCommunicable diseases. 001435293 650_6 $$aPolymorphisme génétique. 001435293 650_6 $$aGénétique humaine. 001435293 650_6 $$aParasitologie. 001435293 650_6 $$aImmunologie. 001435293 650_6 $$aMaladies infectieuses. 001435293 655_0 $$aElectronic books. 001435293 77608 $$iPrint version: $$z9789813347601 001435293 852__ $$bebk 001435293 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-33-4761-8$$zOnline Access$$91397441.1 001435293 909CO $$ooai:library.usi.edu:1435293$$pGLOBAL_SET 001435293 980__ $$aBIB 001435293 980__ $$aEBOOK 001435293 982__ $$aEbook 001435293 983__ $$aOnline 001435293 994__ $$a92$$bISE