001435382 000__ 04352cam\a2200673\i\4500
001435382 001__ 1435382
001435382 003__ OCoLC
001435382 005__ 20230309003851.0
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001435382 008__ 210402s2021\\\\sz\a\\\\ob\\\\000\0\eng\d
001435382 019__ $$a1244626604$$a1253411880$$a1284937912
001435382 020__ $$a9783030688448$$q(electronic bk.)
001435382 020__ $$a3030688445$$q(electronic bk.)
001435382 020__ $$a9783030688455$$q(print)
001435382 020__ $$a3030688453
001435382 020__ $$a9783030688462$$q(print)
001435382 020__ $$a3030688461
001435382 020__ $$z3030688437
001435382 020__ $$z9783030688431
001435382 0247_ $$a10.1007/978-3-030-68844-8$$2doi
001435382 035__ $$aSP(OCoLC)1244535438
001435382 040__ $$aYDX$$beng$$erda$$epn$$cYDX$$dGW5XE$$dEBLCP$$dOCLCO$$dOCLCF$$dVT2$$dLIP$$dUKAHL$$dOCLCQ$$dOCLCO$$dCOM$$dOCLCQ
001435382 049__ $$aISEA
001435382 050_4 $$aQP623
001435382 08204 $$a572.8/8$$223
001435382 1001_ $$aHolvoet, Paul,$$eauthor.
001435382 24510 $$aNon-coding RNAs at the cross-road of cardiometabolic diseases and cancer /$$cPaul Holvoet ; illustrations by Pieterjan Ginckels.
001435382 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2021]
001435382 300__ $$a1 online resource (xxx, 265 pages) :$$billustrations (some color)
001435382 336__ $$atext$$btxt$$2rdacontent
001435382 337__ $$acomputer$$bc$$2rdamedia
001435382 338__ $$aonline resource$$bcr$$2rdacarrier
001435382 347__ $$atext file
001435382 347__ $$bPDF
001435382 504__ $$aIncludes bibliographical references.
001435382 5050_ $$aBiogenesis and Modes of Action Of miRs And Circular And Long Non-coding RNAs -- Non-coding RNAs Related to Obesity -- Non-coding RNAs Related to Type 2 Diabetes -- Non-coding RNAs Related to Lipid Metabolism and Non-Alcoholic Fatty Liver Disease -- Non-coding RNAs Related to Atherosclerosis -- Non-coding RNAs Related to Cardiomyopathy and Heart Failure -- Non-coding RNAs Related to Cardiometabolic Diseases and Associated to Cancer -- Regulation of Non-coding RNAs in Cardiometabolic Tissues and Tumors -- Communication between Tumor-Adjacent Tissues and Tumors with Emphasis on Role of Inflammatory Cells -- The Impact of Non-coding RNA Networks on Disease Comorbidity: Cardiometabolic Diseases, Inflammatory Diseases, and Cancer.
001435382 506__ $$aAccess limited to authorized users.
001435382 520__ $$aThis book gives insight into the functional role of non-coding RNAs in central pathways contributing to the development of obesity, type 2 diabetes, non-alcoholic fatty liver disease, atherosclerosis, myocardial infarction, cardiomyopathy, and heart failure. It also sheds light on the relationship of this cluster with cancer. Tumor cells, in contrast to cells in cardiometabolic tissues, can regulate this cluster of non-coding RNAs to escape from oxidative stress and anti-tumor immunity and maintain insulin sensitivity, facilitating cancer progression. The book presents a cluster of non-coding RNAs that may be prospectively analyzed in extensive cohort studies to determine their value in risk-predicting machine learning algorithms. In addition, it emphasizes the role of microvesicles in communication between tumor-adjacent tissue, inflammatory cells, and tumor cells, with a special focus on the role of miR-155. The book intends to promote interdisciplinary research. Due to the comprehensive background information provided in each chapter, it is suitable for researchers in academia and industry and for graduate students in biology, bioengineering, and medicine.
001435382 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed April 22, 2021).
001435382 650_0 $$aNon-coding RNA.
001435382 650_0 $$aMetabolism$$xDisorders$$xMolecular aspects.
001435382 650_0 $$aCardiovascular system$$xDiseases$$xMolecular aspects.
001435382 650_0 $$aCancer$$xGenetic aspects.
001435382 650_0 $$aGenetic regulation.
001435382 650_6 $$aARN non codants.
001435382 650_6 $$aTroubles du métabolisme$$xAspect moléculaire.
001435382 650_6 $$aAppareil cardiovasculaire$$xMaladies$$xAspect moléculaire.
001435382 650_6 $$aCancer$$xAspect génétique.
001435382 650_6 $$aRégulation génétique.
001435382 655_0 $$aElectronic books.
001435382 7001_ $$aGinckels, Pieterjan,$$eillustrator.
001435382 77608 $$iPrint version:$$z9783030688431$$w(OCoLC)1230231145
001435382 852__ $$bebk
001435382 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-68844-8$$zOnline Access$$91397441.1
001435382 909CO $$ooai:library.usi.edu:1435382$$pGLOBAL_SET
001435382 980__ $$aBIB
001435382 980__ $$aEBOOK
001435382 982__ $$aEbook
001435382 983__ $$aOnline
001435382 994__ $$a92$$bISE