001435404 000__ 03955cam\a2200685\i\4500
001435404 001__ 1435404
001435404 003__ OCoLC
001435404 005__ 20230309003852.0
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001435404 008__ 210402s2021\\\\sz\a\\\\ob\\\\000\0\eng\d
001435404 019__ $$a1244624322$$a1253405623$$a1284935881
001435404 020__ $$a9783030700638$$q(electronic bk.)
001435404 020__ $$a3030700631$$q(electronic bk.)
001435404 020__ $$a9783030700645$$q(print)
001435404 020__ $$a303070064X
001435404 020__ $$a9783030700652$$q(print)
001435404 020__ $$a3030700658
001435404 020__ $$z3030700623
001435404 020__ $$z9783030700621
001435404 0247_ $$a10.1007/978-3-030-70063-8$$2doi
001435404 035__ $$aSP(OCoLC)1244535918
001435404 040__ $$aYDX$$beng$$erda$$epn$$cYDX$$dGW5XE$$dEBLCP$$dOCLCO$$dOCLCF$$dVT2$$dLIP$$dUKAHL$$dOCLCO$$dOCLCQ$$dOCLCO$$dCOM$$dOCLCQ
001435404 049__ $$aISEA
001435404 050_4 $$aRM301.25
001435404 08204 $$a615.1/9$$223
001435404 24500 $$aOrganotypic models in drug development /$$cMonika Schäfer-Korting, Silvya Stuchi Maria-Engler, Robert Landsiedel.
001435404 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2021]
001435404 300__ $$a1 online resource (viii, 323 pages) :$$billustrations (some color)
001435404 336__ $$atext$$btxt$$2rdacontent
001435404 337__ $$acomputer$$bc$$2rdamedia
001435404 338__ $$aonline resource$$bcr$$2rdacarrier
001435404 347__ $$atext file
001435404 347__ $$bPDF
001435404 4901_ $$aHandbook of experimental pharmacology,$$x0171-2004 ;$$vvolume 265
001435404 504__ $$aIncludes bibliographical references.
001435404 5050_ $$aHuman-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- In Vitro Models of the Blood-Brain Barrier -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Engineered Heart Muscle Models in Phenotypic Drug Screens -- Disease Models: Lung Models for Testing Drugs Against Inflammation and Infection -- Skin Disease Models In Vitro and Inflammatory Mechanisms: Predictability for Drug Development -- Immunocompetent Human Intestinal Models in Preclinical Drug Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing.
001435404 506__ $$aAccess limited to authorized users.
001435404 520__ $$aThis book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
001435404 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed April 15, 2021).
001435404 650_0 $$aDrug development.
001435404 650_0 $$aTissue engineering.
001435404 650_0 $$aTissue culture.
001435404 650_0 $$aPharmacology, Experimental.
001435404 650_6 $$aMédicaments$$xDéveloppement.
001435404 650_6 $$aGénie tissulaire.
001435404 650_6 $$aTissus (Histologie)$$xCulture.
001435404 650_6 $$aPharmacologie expérimentale.
001435404 655_0 $$aElectronic books.
001435404 7001_ $$aSchäfer-Korting, Monika,$$d1952-$$eeditor.
001435404 7001_ $$aStuchi Maria-Engler, Silvya,$$eeditor.
001435404 7001_ $$aLandsiedel, Robert,$$eeditor.
001435404 77608 $$iPrint version:$$z9783030700621$$w(OCoLC)1233165147
001435404 830_0 $$aHandbook of experimental pharmacology ;$$vv. 265.$$x0171-2004
001435404 852__ $$bebk
001435404 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-70063-8$$zOnline Access$$91397441.1
001435404 909CO $$ooai:library.usi.edu:1435404$$pGLOBAL_SET
001435404 980__ $$aBIB
001435404 980__ $$aEBOOK
001435404 982__ $$aEbook
001435404 983__ $$aOnline
001435404 994__ $$a92$$bISE