Intro
Contents
1: Introduction of Nanobiotechnology
1.1 Introduction
1.2 What Is Nanotechnology?
1.2.1 How Small Is Nano?
1.2.2 Nanofabrication and Analytical Tools
1.2.3 Exotic Properties of the Nanomaterials
1.3 Classification of Nanomaterials and Their Application
1.3.1 Metal NPs
1.3.2 Magnetic NPs
1.3.3 Quantum Dots (QDs)
1.3.4 Silica NPs
1.3.5 Carbon NPs
1.4 Nanotoxicology and Future Perspective
Bibliography
2: General in Colloidal Nanoparticles
2.1 Introduction
2.2 Fabrication of Nanoparticles

2.2.1 Nucleation and Growth
2.2.1.1 Nucleation
2.2.1.2 Growth Kinetics
2.2.2 Size Control
2.2.2.1 Nucleation Control
2.2.2.2 Ostwald Ripening and Sintering
2.2.2.3 Microemulsion Method (Template-Based Method)
2.3 Stabilization of Nanocrystals Against Aggregation
2.3.1 Aggregation
2.3.2 Surface Charge
2.3.3 Electrical Double Layer
2.3.4 Van der Waals Attraction
2.3.5 DLVO (Derjaguin, Landau, Verwey, Overbeek) Theory
2.3.6 Steric Stabilization
Bibliography
3: Silica Nanoparticles
3.1 Introduction

3.2 Synthesis of Silica Nanoparticles
3.2.1 Stöber Method (Nucleation and Growth)
3.2.2 Reverse Microemulsions
3.2.3 Modified Sol-Gel Method for Silica Coating
3.2.4 Modified Sol-Gel Method for Controlling Shape and Porosity
3.3 Surface Modification for Functionalization of Silica Nanoparticles
3.4 Various Nanoparticles Applied to Silica
3.4.1 Various Silica-Coated Nanoparticles
3.4.2 Porous Silica Nanoparticles
3.4.3 Synthesis of Various Nanoparticles Using Silica as a Template
3.5 Various Silica-Applied Nanoparticles for Bioapplications

3.5.1 Biosensing and Bioimaging for Diagnostics
3.5.2 Drug Delivery
3.5.3 Multifunctional Silica Nanoparticles
3.6 Conclusion
Bibliography
4: Luminescent Nanomaterials (I)
4.1 Introduction
4.2 Basics of Fluorescence
4.2.1 Light and Luminescence
4.2.2 Fluorescence Process and Related Terminologies
4.2.3 Organic Dyes As Fluorophores
4.3 Luminescent Nanoparticles
4.3.1 Fluorescence Organic Dye-Incorporated Materials
4.3.1.1 Dye-Doped Silica Nanoparticles
4.3.1.2 Fluorescence-Encoded Beads
4.3.2 Quantum Dots (QD)

4.3.2.1 Fundamentals of QDs
Quantum Confinement Effect
Optical Properties
Quantum Yield and Surface Structures
4.3.2.2 Synthesis of Quantum Dots
4.3.2.3 Surface Modifications
4.3.3 Upconversion Fluorescent Nanoparticles
4.3.3.1 Fundamentals of UCNPs
4.3.3.2 Synthesis and Surface Modification of UCNPs
4.3.4 Other Luminescent Nanomaterials
4.3.4.1 Europium-Based Materials
4.3.4.2 Noble Metal Nanoclusters
4.3.4.3 Other Carbon-Based QDs
References
5: Luminescent Nanomaterials (II)
5.1 Sensing Mechanisms and Techniques