The neuropathology of schizophrenia / Matthew Williams, editor.
2021
RC514
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Title
The neuropathology of schizophrenia / Matthew Williams, editor.
ISBN
9783030683085 (electronic bk.)
3030683087 (electronic bk.)
9783030683061
3030683060
3030683087 (electronic bk.)
9783030683061
3030683060
Published
Cham, Switzerland : Springer, [2021]
Language
English
Description
1 online resource
Item Number
10.1007/978-3-030-68308-5 doi
Call Number
RC514
Dewey Decimal Classification
616.89/807
Summary
In the past few decades, neuropathology has witnessed a resurgence. The rise of structural and functional imaging techniques has allowed pathological studies to target regions of special interest as revealed by whole-brain techniques, and the development of comprehensive software packages has facilitated cellular and pathological measurements. Furthermore, a new generation of antibodies and improved staining methods has made the field more accessible to researchers and revealed more detail than could once have been envisaged. Perhaps most important of all has been the sourcing of high-quality tissue through modern, large-scale databases covering multiple tissue banks, removing much of the heterogeneity that had made repeat studies all but impossible. The Neuropathology of Schizophrenia reviews the field following these recent improvements in techniques and contrasting more modern methods against older studies. This book presents the current state of neuropathological knowledge in schizophrenia by means of examination of neuropathology as informed by functional systems. It starts by considering the frontal cortical region, a particularly well-examined region of the brain, before moving through other cortical regions, subcortical pathways and the deep white matter. In addition, potential new routes for investigation are considered, particularly in glial cells.
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Online resource; title from PDF title page (SpringerLink, viewed April 14, 2021).
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Print version: 9783030683061
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Table of Contents
Introduction
A note of neuroanatomy
Gross Pathology in Schizophrenia
Frontal Cortex
Temporal Cortex
The amygdala, hippocampus, fornix and nucleus basalis
The Cingulate Cortex
Parietal and Occipital Lobes
The Basal Ganglia
The Thalamus
The Neuropathology of White Matter in Schizophrenia
Glial Cells.
A note of neuroanatomy
Gross Pathology in Schizophrenia
Frontal Cortex
Temporal Cortex
The amygdala, hippocampus, fornix and nucleus basalis
The Cingulate Cortex
Parietal and Occipital Lobes
The Basal Ganglia
The Thalamus
The Neuropathology of White Matter in Schizophrenia
Glial Cells.