001435607 000__ 03506cam\a2200613\i\4500 001435607 001__ 1435607 001435607 003__ OCoLC 001435607 005__ 20230309003944.0 001435607 006__ m\\\\\o\\d\\\\\\\\ 001435607 007__ cr\cn\nnnunnun 001435607 008__ 210410s2021\\\\sz\\\\\\o\\\\\000\0\eng\d 001435607 019__ $$a1244805782 001435607 020__ $$a9783030648534$$q(electronic bk.) 001435607 020__ $$a3030648532$$q(electronic bk.) 001435607 020__ $$z9783030648527 001435607 020__ $$z3030648524 001435607 0247_ $$a10.1007/978-3-030-64853-4$$2doi 001435607 035__ $$aSP(OCoLC)1245665019 001435607 040__ $$aEBLCP$$beng$$erda$$epn$$cEBLCP$$dGW5XE$$dYDX$$dOCLCO$$dYDX$$dOCLCF$$dOCLCQ$$dOCLCO$$dOCLCQ 001435607 049__ $$aISEA 001435607 050_4 $$aQD251$$b.P76 2021 001435607 08204 $$a547$$223 001435607 24500 $$aProgress in the chemistry of organic natural products.$$nVolume 115 /$$cA. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch, editors. 001435607 264_1 $$aCham :$$bSpringer,$$c2021. 001435607 300__ $$a1 online resource (210 pages) 001435607 336__ $$atext$$btxt$$2rdacontent 001435607 337__ $$acomputer$$bc$$2rdamedia 001435607 338__ $$aonline resource$$bcr$$2rdacarrier 001435607 4901_ $$aProgress in the Chemistry of Organic Natural Products ;$$vv. 115 001435607 5050_ $$aTotal Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis -- From Plant to Patient: Thapsigargin -- Antileishmanial Activity of Lignans and Neolignans -- Cryptolepine as a Lead to new Antiprotozoal Agents -- Biologically Active Constituents from Plants of the Genus Xanthium. 001435607 506__ $$aAccess limited to authorized users. 001435607 520__ $$aThis book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer. 001435607 588__ $$aDescription based on print version record. 001435607 650_0 $$aChemistry, Organic. 001435607 650_0 $$aPharmaceutical chemistry. 001435607 650_0 $$aClinical biochemistry. 001435607 650_6 $$aChimie organique. 001435607 650_6 $$aChimie pharmaceutique. 001435607 650_6 $$aBiochimie clinique. 001435607 655_0 $$aElectronic books. 001435607 7001_ $$aKinghorn, A. Douglas. 001435607 7001_ $$aFalk, Heinz,$$d1939- 001435607 7001_ $$aGibbons, Simon$$c(Professor of medicinal phytochemistry) 001435607 7001_ $$aAsakawa, Yoshinori. 001435607 7001_ $$aLiu, Ji-Kai. 001435607 7001_ $$aDirsch, Verena M. 001435607 77608 $$iPrint version:$$aKinghorn, A. Douglas.$$tProgress in the Chemistry of Organic Natural Products 115.$$dCham : Springer International Publishing AG, ©2021$$z9783030648527 001435607 830_0 $$aProgress in the chemistry of organic natural products (2011) ;$$v115. 001435607 852__ $$bebk 001435607 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-64853-4$$zOnline Access$$91397441.1 001435607 909CO $$ooai:library.usi.edu:1435607$$pGLOBAL_SET 001435607 980__ $$aBIB 001435607 980__ $$aEBOOK 001435607 982__ $$aEbook 001435607 983__ $$aOnline 001435607 994__ $$a92$$bISE