Progress in the chemistry of organic natural products. Volume 115 / A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch, editors.
2021
QD251 .P76 2021
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Title
Progress in the chemistry of organic natural products. Volume 115 / A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch, editors.
ISBN
9783030648534 (electronic bk.)
3030648532 (electronic bk.)
9783030648527
3030648524
3030648532 (electronic bk.)
9783030648527
3030648524
Published
Cham : Springer, 2021.
Language
English
Description
1 online resource (210 pages)
Item Number
10.1007/978-3-030-64853-4 doi
Call Number
QD251 .P76 2021
Dewey Decimal Classification
547
Summary
This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.
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Series
Progress in the chemistry of organic natural products (2011) ; 115.
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Table of Contents
Total Synthesis of Decanolides (Nonanolides) with a Special Focus on Olefin Metathesis
From Plant to Patient: Thapsigargin
Antileishmanial Activity of Lignans and Neolignans
Cryptolepine as a Lead to new Antiprotozoal Agents
Biologically Active Constituents from Plants of the Genus Xanthium.
From Plant to Patient: Thapsigargin
Antileishmanial Activity of Lignans and Neolignans
Cryptolepine as a Lead to new Antiprotozoal Agents
Biologically Active Constituents from Plants of the Genus Xanthium.