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001435620 020__ $$a9783030578398$$q(electronic bk.)
001435620 020__ $$a3030578399$$q(electronic bk.)
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001435620 0247_ $$a10.1007/978-3-030-57839-8$$2doi
001435620 035__ $$aSP(OCoLC)1245666405
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001435620 049__ $$aISEA
001435620 050_4 $$aRC647.H97
001435620 08204 $$a616.1/50654$$223
001435620 24500 $$aNutritional management and metabolic aspects of Hyperhomocysteinemia /$$cMostafa I. Waly, editor.
001435620 264_1 $$aCham :$$bSpringer,$$c2021.
001435620 300__ $$a1 online resource (274 pages)
001435620 336__ $$atext$$btxt$$2rdacontent
001435620 337__ $$acomputer$$bc$$2rdamedia
001435620 338__ $$aonline resource$$bcr$$2rdacarrier
001435620 347__ $$atext file
001435620 347__ $$bPDF
001435620 500__ $$a2 Dietary Factors Contributed to Hyperhomocysteinemia.
001435620 5050_ $$aIntro -- Preface -- Contents -- Contributors -- About the Editor -- Chapter 1: Signaling Pathways of Hyperhomocystenemia and Oxidative Stress -- 1 Introduction -- 2 Cofactors for Re-Methylation and Trans-Sulfuration Pathways -- 2.1 Folate -- 2.2 Vitamin B12 -- 2.3 Vitamin B6 -- 3 Hyperhomocysteinemia and Oxidative Stress -- 4 Conclusion -- References -- Chapter 2: Hyperhomocysteinemia and Cancer: The Role of Natural Products and Nutritional Interventions -- 1 Introduction -- 2 Biosynthesis of Homocysteine -- 3 Metabolism of Homocysteine -- 3.1 Remethylation -- 3.2 Transsulfuration
001435620 5058_ $$a4 Hyperhomocysteinemia Induction -- 4.1 Genetic Enzymatic Defects -- 4.2 Absence/Inadequate Amounts of Certain Cofactors -- 4.3 Excessive Methionine Consumption -- 5 Diseases Associated with Hyperhomocysteinemia -- 5.1 Chronic Renal Failure -- 5.2 Hypothyroidism -- 5.3 Anemia -- 5.4 Malignant Tumors -- 5.5 Medications -- 6 Hyperhomocysteinemia and Cancer -- 7 Hyperhomocysteinemia Management Using Natural Products and Diet -- 8 Conclusion -- References -- Chapter 3: Anti-inflammatory Role of Anthocyanins in the Prevention of Hyperhomocysteinemia-Mediated Cardiometabolic Diseases -- 1 Introduction
001435620 5058_ $$a2 Inflammation -- 3 Inflammation and Hyperhomocysteinemia -- 4 Cardiometabolic Diseases and Plant Polyphenols -- 5 Homocysteine and Anthocyanins -- 6 Anthocyanins: The Treasure of Health -- 6.1 Chemical Structure and Chemistry of Anthocyanins -- 6.2 Anthocyanin and Inflammation -- 7 Conclusion -- References -- Chapter 4: Metabolic Role of Hyperhomocysteinemia in the Etiology of Chronic Diseases -- 1 Introduction -- 2 Homocysteine Metabolism -- 3 Hyperhomocysteinemia and Neurological Disorders -- 3.1 Stroke -- 3.2 Mild Cognitive Impairment (MCI), and Dementia -- 3.3 Parkinson's Disease (PD)
001435620 5058_ $$a3.4 Epilepsy -- 4 Hyperhomocysteinemia and Cardiovascular Diseases -- 5 Hyperhomocysteinemia and Cancer -- 6 Conclusion -- References -- Chapter 5: B-Vitamins Attenuates Preliminary Steps of Hyperhomocysteinemia and Colorectal Cancer -- 1 Introduction -- 2 Dietary and Non-dietary Risk Factors for Colorectal Cancer -- 3 B-Vitamins, Glutathione and Colorectal Cancer -- 4 Hyperhomocysteinemia and Colorectal Cancer -- 5 Conclusion -- References -- Chapter 6: Hyperhomocysteinemia, B-Vitamins, and Coronary Artery Disease Risk -- 1 Introduction
001435620 5058_ $$a2 Sulfur Metabolism and Pathogenesis of Coronary Artery Disease -- 3 Hyperhomocysteinemia and Coronary Artery Disease -- 4 B-Vitamins Therapy and CAD -- 5 Conclusion -- References -- Chapter 7: Potential Role of Hyperhomocysteinemia in Prediabetes Etiology and Pathology -- 1 Introduction -- 2 B-vitamins, Oxidative Stress and Prediabetes Risk -- 3 Hyperhomocysteinemia and the Pathogenesis of Prediabetes and Type 2 Diabetes -- 4 Current Research -- 5 Conclusion -- References -- Chapter 8: Genetic Risk Factors in the Development of Hyperhomocysteinemia -- 1 Introduction
001435620 506__ $$aAccess limited to authorized users.
001435620 520__ $$aElevated blood concentrations of homocysteine, B vitamins deficiencies and oxidative stress are etiological factors for many human chronic diseases, yet the etiologic relationship of hyperhomocysteinemia to these disorders remains poorly understood. Clinical trials continue to support the notion that hyperhomocysteinemia is involved in the pathogenesis of oxidative stress and its associated impairment of cellular redox status. Antioxidants, phytochemicals, and bioactive agents are thought to be associated with the reduction of oxidative stress and reducing risk of chronic diseases, yet their role in preventing hyperhomocysteinemia-mediated oxidative stress has not been well covered in the literature. Nutritional Management and Metabolic Aspects and of Hyperhomocysteinemia comprehensively covers the nutritional-based intervention for combating hyperhomocysteinemia-mediated oxidative stress, metabolic regulation of homocysteine-dependent transulfuration and transmethylation pathways, and the identification of novel biomarkers for early diagnosis of hyperhomocysteinemia. The main goal of this text is to address the biochemical and nutritional aspects of hyperhomocysteinemia in relation to increasing risk of chronic diseases, providing insight into the etiology of hyperhomocysteinemia and covering new research on the effective reduction and management of hyperhomocysteinemia-associated chronic diseases. For researchers seeking a singular source for the understanding of the biochemical aspects and nutrition-based combat of hyperhomocysteinemia, its risk factors, preventive measures, and possible treatments currently available, this text provides all of the important needed information in up-to-date and comprehensive form.
001435620 588__ $$aDescription based on print version record.
001435620 650_0 $$aBlood$$xDiseases$$xDiet therapy.
001435620 650_0 $$aBlood$$xDiseases$$xNutritional aspects.
001435620 650_0 $$aHomocysteine.
001435620 650_6 $$aSang$$xMaladies$$xDiétothérapie.
001435620 650_6 $$aSang$$xMaladies$$xAspect nutritionnel.
001435620 650_6 $$aHomocystéine.
001435620 655_0 $$aElectronic books.
001435620 7001_ $$aWaly, Mostafa I.,$$eeditor.
001435620 77608 $$iPrint version:$$aWaly, Mostafa I.$$tNutritional Management and Metabolic Aspects of Hyperhomocysteinemia.$$dCham : Springer International Publishing AG, ©2021$$z9783030578381
001435620 852__ $$bebk
001435620 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-57839-8$$zOnline Access$$91397441.1
001435620 909CO $$ooai:library.usi.edu:1435620$$pGLOBAL_SET
001435620 980__ $$aBIB
001435620 980__ $$aEBOOK
001435620 982__ $$aEbook
001435620 983__ $$aOnline
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