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Intro
Foreword
Foreword
Preface
Acknowledgments
Contents
Case Studies in Cleft Surgery
About the Editors
Editor
Illustrator
Section Editors
Contributors
Part I: Introduction to Global Cleft Care
1: Introduction: A Paradigm Shift in Global Cleft Care
Five Forces Shaping Global Cleft Care
Surgery as Public Health
Locally Delivered Cleft Care
Focus on Achieving Great Patient Outcomes
Innovation Borne of Low-Resource Settings
The Conundrum of Evidence-Based Medicine
References
2: Burden of Cleft Disease and Opportunity for Impact

Introduction
Defining Cleft Conditions
The Burden of Cleft Disease
Epidemiology
Outcomes for Cleft Patients
Economics of Cleft Care
Approaches to Cleft Care
Defining Adequate Cleft Care
Methods of Reaching Untreated or Undertreated Patients
The Potential Impact of Cleft Care
References
3: Patient Barriers to Care
Introduction
Availability of Care (Supply)
Workforce
Infrastructure
Affordability and Acceptability of Surgical Care (Demand)
Affordability
Acceptability
Conclusion
References
4: Innovations in Reaching Patients

Introduction
Design Thinking
Examples from the Field
Cleft Lip and Palate
Patient Accompaniment: Partners in Health and Operation Smile Honduras
Problem Statement
Program Overview
Why It Works
Enhancing the Patient Experience: Operation Smile, Madagascar
Problem Statement
Program Overview
Why It Works
Primary Care
Nuka System of Care: Southcentral Foundation, Alaska, United States
Problem Statement
Program Overview
Why It Works
Community Health Workers: Last Mile Health, Liberia
Problem Statement
Program Overview
Why it Works

Infectious Disease
Community-Based Surveillance System: CORE Group Polio Project, South Sudan
Problem Statement
Program Overview
Why It Works
Conclusion & Key Takeaways
References
Part II: Patient and Cleft Assessment
5: Patterns, Anatomy, and Classification of Clefts
Introduction
Epidemiology
Patterns of Cleft Lip and Palate
Syndromic Clefts
Racial and Ethnic Epidemiologic Variations
Embryology
The Gene-Environment Interplay
Facial Development
Clefts as Failure of Fusion Events
Cleft-Related Anatomy

Nose: Tip, Alae, Columella, Nasal Sill, Paranasal Muscles
Palate
Classification
Severity Classification
Patterns
Unilateral Cleft Lip and Palate (UCLPA): Main Features
Bilateral Cleft Lip and Palate (BCLPA): Main Features
Cleft Palate: Main Features
References
6: Early Nutrition, Feeding and Management of Infants with an Oral Cleft
Introduction
Feeding Guidance for Patients with Cleft Lip/Palate
Normal Feeding
Feeding Duration and Amounts
Initial Feeding Assessment
Specific Feeding Problems of Infants with CL+/− P
Cleft Lip

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