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001436010 001__ 1436010
001436010 003__ OCoLC
001436010 005__ 20230309004004.0
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001436010 008__ 210426s2021\\\\sz\a\\\\o\\\\\000\0\eng\d
001436010 019__ $$a1249014014$$a1249270383
001436010 020__ $$a9783030716561$$q(electronic bk.)
001436010 020__ $$a3030716562$$q(electronic bk.)
001436010 020__ $$z9783030716554$$q(print)
001436010 020__ $$z3030716554
001436010 0247_ $$a10.1007/978-3-030-71656-1$$2doi
001436010 035__ $$aSP(OCoLC)1247681820
001436010 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dOCLCO$$dYDX$$dEBLCP$$dOCLCF$$dOCLCO$$dN$T$$dUKAHL$$dOCLCO$$dOCLCQ$$dCOM$$dOCLCO$$dOCLCQ
001436010 049__ $$aISEA
001436010 050_4 $$aTP248.3
001436010 08204 $$a660.6/3$$223
001436010 24500 $$aDigital twins :$$bapplications to the design and optimization of bioprocesses /$$cChristoph Herwig, Ralf Pörtner, Johannes Möller, editors ; with contributions by E. Anane [and more].
001436010 2463_ $$aApplications to the design and optimization of bioprocesses
001436010 264_1 $$aCham, Switzerland :$$bSpringer,$$c2021.
001436010 300__ $$a1 online resource (vii, 254 pages) :$$billustrations (some color)
001436010 336__ $$atext$$btxt$$2rdacontent
001436010 337__ $$acomputer$$bc$$2rdamedia
001436010 338__ $$aonline resource$$bcr$$2rdacarrier
001436010 4901_ $$aAdvances in biochemical engineering/biotechnology,$$x0724-6145 ;$$v177
001436010 5050_ $$aPotential of model-based design of experiments approaches for bioprocess scale-down -- Digital Twins and Their Role in Model-Assisted Design of Experiments -- Digital twins for bioprocess control strategy development and realization -- The Kalman filter for the supervision of cultivation processes.-The challenge of implementing digital twins in operating value chains -- Digital twins in the (bio)pharma industry -- Numerical methods for the design and description of in vitro expansion processes of human mesenchymal stem cells -- Euler-Lagrangian Simulations: A Proper Tool for Predicting Cellular Performance in Industrial Scale Bioreactors.
001436010 506__ $$aAccess limited to authorized users.
001436010 520__ $$aThis is the second of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization. Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into the 21st-century digitalization of the bioprocess industry. Moreover, the high demand for biotechnological products calls for efficient methods during research and development, as well as during tech transfer and routine manufacturing. In this regard, one promising tool is the use of digital twins, which offer a virtual representation of the bioprocess. They reflect the mechanistics of the biological system and the interactions between process parameters, key performance indicators and product quality attributes in the form of a mathematical process model. Furthermore, digital twins allow us to use computer-aided methods to gain an improved process understanding, to test and plan novel bioprocesses, and to efficiently monitor them. This book focuses on the application of digital twins in various contexts, e.g. computer-aided experimental design, seed train prediction, and lifeline analysis. Covering fundamentals as well as applications, the two volumes offers the ideal introduction to the topic for researchers in academy and industry alike.
001436010 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed April 26, 2021).
001436010 650_0 $$aBiochemical engineering.
001436010 650_0 $$aBiomedical engineering.
001436010 650_6 $$aGénie biochimique.
001436010 650_6 $$aGénie biomédical.
001436010 655_0 $$aElectronic books.
001436010 7001_ $$aHerwig, Christoph,$$eeditor.
001436010 7001_ $$aPörtner, Ralf,$$eeditor.
001436010 7001_ $$aMöller, Johannes,$$eeditor.
001436010 77608 $$iPrint version:$$z3030716554$$z9783030716554$$w(OCoLC)1237632593
001436010 830_0 $$aAdvances in biochemical engineering/biotechnology ;$$v177.$$x0724-6145
001436010 852__ $$bebk
001436010 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-71656-1$$zOnline Access$$91397441.1
001436010 909CO $$ooai:library.usi.edu:1436010$$pGLOBAL_SET
001436010 980__ $$aBIB
001436010 980__ $$aEBOOK
001436010 982__ $$aEbook
001436010 983__ $$aOnline
001436010 994__ $$a92$$bISE