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001436011 001__ 1436011
001436011 003__ OCoLC
001436011 005__ 20230309004004.0
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001436011 008__ 210426s2021\\\\sz\a\\\\o\\\\\000\0\eng\d
001436011 019__ $$a1249013333
001436011 020__ $$a9783030716608$$q(electronic bk.)
001436011 020__ $$a3030716600$$q(electronic bk.)
001436011 020__ $$z9783030716592$$q(print)
001436011 020__ $$z3030716597
001436011 0247_ $$a10.1007/978-3-030-71660-8$$2doi
001436011 035__ $$aSP(OCoLC)1247681854
001436011 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dOCLCO$$dYDX$$dEBLCP$$dOCLCF$$dOCLCO$$dUKAHL$$dN$T$$dOCLCO$$dOCLCQ$$dCOM$$dOCLCQ
001436011 049__ $$aISEA
001436011 050_4 $$aTP248.3
001436011 08204 $$a660.6/3$$223
001436011 24500 $$aDigital twins :$$btools and concepts for smart biomanufacturing /$$cChristoph Herwig, Ralf Pörtner, Johannes Möller, editors ; with contributions by C. Appl [and more].
001436011 2463_ $$aTools and concepts for smart biomanufacturing
001436011 264_1 $$aCham, Switzerland :$$bSpringer,$$c[2021]
001436011 300__ $$a1 online resource (vii, 262 pages) :$$billustrations (some color)
001436011 336__ $$atext$$btxt$$2rdacontent
001436011 337__ $$acomputer$$bc$$2rdamedia
001436011 338__ $$aonline resource$$bcr$$2rdacarrier
001436011 4901_ $$aAdvances in Biochemical Engineering/Biotechnology,$$x0724-6145 ;$$v176
001436011 5050_ $$aTowards the development of digital twins for the biomanufacturing industry -- When is an In silico representation a digital twin? A biopharmaceutical industry approach to the digital twin concept -- Digitalization and bioprocessing, regulatory aspects -- Usage of Digital Twins along a typical process development cycle -- Mechanistic Mathematical Models as a Basis for Process Optimization and Digital Twins -- Digital Seed Train Twins and Statistical Methods -- Digital Twins in Biomanufacturing.
001436011 506__ $$aAccess limited to authorized users.
001436011 520__ $$aThis is the first of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization. Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into the 21st-century digitalization of the bioprocess industry. Moreover, the high demand for biotechnological products calls for efficient methods during research and development, as well as during tech transfer and routine manufacturing. In this regard, one promising tool is the use of digital twins, which offer a virtual representation of the bioprocess. They reflect the mechanistics of the biological system and the interactions between process parameters, key performance indicators and product quality attributes in the form of a mathematical process model. Furthermore, digital twins allow us to use computer-aided methods to gain an improved process understanding, to test and plan novel bioprocesses, and to efficiently monitor them. This book explains the mathematical structure of digital twins, their development and the model's respective parts, as well as concepts for the knowledge-driven generation and structural variability of digital twins. Covering fundamentals as well as applications, the two volumes offer the ideal introduction to the topic for researchers in academy and industry alike.
001436011 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed April 26, 2021).
001436011 650_0 $$aBiochemical engineering.
001436011 650_0 $$aBiomedical engineering.
001436011 650_6 $$aGénie biochimique.
001436011 650_6 $$aGénie biomédical.
001436011 655_0 $$aElectronic books.
001436011 7001_ $$aHerwig, Christoph,$$eeditor.
001436011 7001_ $$aPörtner, Ralf,$$eeditor.
001436011 7001_ $$aMöller, Johannes,$$eeditor.
001436011 77608 $$iPrint version:$$z3030716597$$z9783030716592$$w(OCoLC)1237630869
001436011 830_0 $$aAdvances in biochemical engineering/biotechnology ;$$v176.$$x0724-6145
001436011 852__ $$bebk
001436011 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-71660-8$$zOnline Access$$91397441.1
001436011 909CO $$ooai:library.usi.edu:1436011$$pGLOBAL_SET
001436011 980__ $$aBIB
001436011 980__ $$aEBOOK
001436011 982__ $$aEbook
001436011 983__ $$aOnline
001436011 994__ $$a92$$bISE