TY - GEN AB - This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field. AU - Sameer, Aga Syed, AU - Banday, Mujeeb Zafar, AU - Nissar, Saniya, CN - RC268.4 CY - Singapore : DA - 2021. DO - 10.1007/978-981-33-6699-2 DO - doi ID - 1436133 KW - Cancer KW - Cancer KW - Genetic polymorphisms. KW - Cancer KW - Polymorphisme génétique. LK - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-33-6699-2 N2 - This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field. PB - Springer, PP - Singapore : PY - 2021. SN - 9789813366992 SN - 9813366990 T1 - Genetic polymorphism and cancer susceptibility / TI - Genetic polymorphism and cancer susceptibility / UR - https://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-33-6699-2 ER -