001436514 000__ 04655cam\a2200517\a\4500 001436514 001__ 1436514 001436514 003__ OCoLC 001436514 005__ 20230309004030.0 001436514 006__ m\\\\\o\\d\\\\\\\\ 001436514 007__ cr\un\nnnunnun 001436514 008__ 210512s2021\\\\sz\\\\\\o\\\\\001\0\eng\d 001436514 020__ $$a9783030698522$$q(electronic bk.) 001436514 020__ $$a3030698521$$q(electronic bk.) 001436514 020__ $$z3030698513 001436514 020__ $$z9783030698515 001436514 0247_ $$a10.1007/978-3-030-69852-2$$2doi 001436514 035__ $$aSP(OCoLC)1250347523 001436514 040__ $$aYDX$$beng$$epn$$cYDX$$dGW5XE$$dEBLCP$$dOCLCO$$dOCLCF$$dUKAHL$$dOCLCQ$$dCOM$$dCASUM$$dOCLCQ 001436514 049__ $$aISEA 001436514 050_4 $$aRC280.H4 001436514 08204 $$a616.99/491$$223 001436514 24500 $$aEarly detection and treatment of head & neck cancers :$$btheoretical background and newly emerging research /$$cRami El Assal, Dyani Gaudilliere, Stephen Thaddeus Connelly, editors. 001436514 2463_ $$aTheoretical background and newly emerging research 001436514 260__ $$aCham, Switzerland :$$bSpringer,$$c2021. 001436514 300__ $$a1 online resource 001436514 336__ $$atext$$btxt$$2rdacontent 001436514 337__ $$acomputer$$bc$$2rdamedia 001436514 338__ $$aonline resource$$bcr$$2rdacarrier 001436514 500__ $$aIncludes index. 001436514 5050_ $$aEpidemiology of Head and Neck Cancers -- Epidemiology of Head and Neck Premalignant Lesions -- Mutational Landscape of Head and Neck Cancers -- Genomic and Proteomic Factors of Head and Neck Cancer Progression -- Understanding the Role of Exosomes in Molecular Pathogenesis of Cancers including Head and Neck Cancers -- Risk of Head and Neck Cancers in Systemic Inflammatory Disorders and after Immunosuppressive Treatment -- Metastasis of Brain Tumors (including Glioblastoma) to Head and Neck Region -- Virus-associated Head and Neck Cancers in Immunocompromised and Healthy Patients -- Orofacial Pain-/Oral Adverse Event-associated with Head and Neck Cancers -- EGFR Activation Signature and Modulation in Head and Neck Cancers -- Identification of Genetic Differences between Normal and Tumor Tissues in Head and Neck Cancers -- Cellular Immune Mechanisms of Natural Killer (NK) Cell, Dendritic Cells (DC) and T Lymphocyte Activation Against Head and Neck Cancers -- Statistical Power Analysis in Head and Neck Cancer Studies -- Bioethics in Head and Neck Cancer Research -- Future Perspective of Head and Neck Cancer Research. 001436514 506__ $$aAccess limited to authorized users. 001436514 520__ $$aHead and neck cancer (HNC) is a heterogeneous group of cancers that, if combined, represent one of the most common cancer types. Patients with HNC suffer significant morbidity and mortality due to the importance of the structures involved. Over two-thirds of these patients are diagnosed at a late stage, leading to a poor prognosis. Therefore, advancements in early detection and treatment of HNC are crucial. This second volume provides an up-to-date overview of the theoretical background in the field of head and neck cancer (HNC) as well as of the emerging research that is impacting our understanding of this disease. The book begins with a comprehensive review of the epidemiology, etiology, symptoms, diagnosis, and staging of HNC. Next, it covers the essentials of potentially malignant disorders of the oral cavity, an important variety of HNC. Subsequently, it covers the newly emerging research in the field of HNC. The overall goal is to shift towards precision medicine (discussed in detail in Volume I), which will bring individualized clinical benefit to patients with HNC. This second volume of Early Detection and Treatment of Head & Neck Cancers concludes with the topic of chronic pain associated with HNC, including both the mechanisms of pain and the management strategies, and the emerging oral mucoadhesive drug delivery approach for HNC. All HNC surgeons, scientists, residents, and individuals whose lives have been touched by this disease, will recognize the impact pain has upon a patients health and his or her recovery trajectory. 001436514 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed May 17, 2021). 001436514 650_0 $$aHead$$xCancer. 001436514 650_0 $$aNeck$$xCancer. 001436514 655_0 $$aElectronic books. 001436514 7001_ $$aEl Assal, Rami,$$eeditor. 001436514 7001_ $$aGaudilliere, Dyani,$$eeditor. 001436514 7001_ $$aConnelly, Stephen Thaddeus,$$eeditor. 001436514 77608 $$iPrint version:$$tEarly detection and treatment of head & neck cancers.$$dCham, Switzerland : Springer, 2021$$z3030698513$$z9783030698515$$w(OCoLC)1233163804 001436514 852__ $$bebk 001436514 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-69852-2$$zOnline Access$$91397441.1 001436514 909CO $$ooai:library.usi.edu:1436514$$pGLOBAL_SET 001436514 980__ $$aBIB 001436514 980__ $$aEBOOK 001436514 982__ $$aEbook 001436514 983__ $$aOnline 001436514 994__ $$a92$$bISE