001436661 000__ 03626cam\a2200517\a\4500 001436661 001__ 1436661 001436661 003__ OCoLC 001436661 005__ 20230309004106.0 001436661 006__ m\\\\\o\\d\\\\\\\\ 001436661 007__ cr\un\nnnunnun 001436661 008__ 210519s2021\\\\sz\\\\\\o\\\\\000\0\eng\d 001436661 020__ $$a9783030675929$$q(electronic bk.) 001436661 020__ $$a3030675920$$q(electronic bk.) 001436661 020__ $$z3030675912 001436661 020__ $$z9783030675912 001436661 0247_ $$a10.1007/978-3-030-67592-9$$2doi 001436661 035__ $$aSP(OCoLC)1251764832 001436661 040__ $$aYDX$$beng$$epn$$cYDX$$dGW5XE$$dEBLCP$$dOCLCO$$dOCLCF$$dUKAHL$$dOCLCQ$$dCOM$$dOCLCO$$dOCLCQ 001436661 049__ $$aISEA 001436661 050_4 $$aQP552.C6 001436661 08204 $$a572/.67$$223 001436661 24504 $$aThe collagen superfamily and collagenopathies /$$cFlorence Ruggiero, editor. 001436661 260__ $$aCham :$$bSpringer,$$c2021. 001436661 300__ $$a1 online resource 001436661 336__ $$atext$$btxt$$2rdacontent 001436661 337__ $$acomputer$$bc$$2rdamedia 001436661 338__ $$aonline resource$$bcr$$2rdacarrier 001436661 4901_ $$aBiology of extracellular matrix,$$x0887-3224 ;$$vv. 8 001436661 5050_ $$aChapter 1: Introduction to the collagen superfamily -- Chapter 2: Collagen IV-related disease -- Chapter 3: Articular collagens related diseases -- Chapter 4: Collagens as new players of nervous system disease -- Chapter 5: Collagens and EDS -- Chapter 6: Collagens and dystrophic epidermolysis bullosa -- Chapter 7: Collagen-related myopathies: pathogenic mechanisms and prospective therapies -- Chapter 8: Procollagen trafficking and its implicaitons in Osteogenesis Imperfecta. 001436661 506__ $$aAccess limited to authorized users. 001436661 520__ $$aThis book aims at providing insights into the collagen superfamily and the remarkable diversity of collagen function within the extracellular matrix. Additionally, the mechanisms underlying collagen-related diseases such as dystrophic epidermolysis bullosa, osteogenesis imperfecta, as well as collagen-related myopathies and neurological disorders are discussed. Collagens are the most abundant extracellular matrix proteins in organisms. Their primary function is to provide structural support and strength to cells and to maintain biomechanical integrity of tissues. However, collagens can no longer be considered just as structural proteins. They can act as extracellular modulators of signaling events and serve critical regulatory roles in various cell functions during embryonic development and adult homeostasis. Furthermore, collagens are associated with a broad spectrum of heritability-related diseases known as collagenopathies that affect a multitude of organs and tissues including sensorial organs. The book is a useful introduction to the field for junior scientists, interested in extracellular matrix research. It is also an interesting read for advanced scientists and clinicians working on collagens and collagenopathies, giving them a broader view of the field beyond their area of specialization. 001436661 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed May 21, 2021). 001436661 650_0 $$aCollagen. 001436661 650_0 $$aConnective tissues. 001436661 650_6 $$aCollagène. 001436661 650_6 $$aTissu conjonctif. 001436661 655_0 $$aElectronic books. 001436661 7001_ $$aRuggiero, Florence,$$eeditor. 001436661 77608 $$iPrint version:$$tCollagen superfamily and collagenopathies.$$dCham : Springer, 2021$$z3030675912$$z9783030675912$$w(OCoLC)1227268619 001436661 830_0 $$aBiology of extracellular matrix ;$$vv. 8.$$x0887-3224 001436661 852__ $$bebk 001436661 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-67592-9$$zOnline Access$$91397441.1 001436661 909CO $$ooai:library.usi.edu:1436661$$pGLOBAL_SET 001436661 980__ $$aBIB 001436661 980__ $$aEBOOK 001436661 982__ $$aEbook 001436661 983__ $$aOnline 001436661 994__ $$a92$$bISE