001436687 000__ 05695cam\a2200517\i\4500 001436687 001__ 1436687 001436687 003__ OCoLC 001436687 005__ 20230309004108.0 001436687 006__ m\\\\\o\\d\\\\\\\\ 001436687 007__ cr\cn\nnnunnun 001436687 008__ 210520s2021\\\\si\a\\\\o\\\\\000\0\eng\d 001436687 019__ $$a1251511975 001436687 020__ $$a9789813296206$$q(electronic bk.) 001436687 020__ $$a9813296208$$q(electronic bk.) 001436687 020__ $$z9789813296190$$q(print) 001436687 020__ $$z9813296194 001436687 0247_ $$a10.1007/978-981-32-9620-6$$2doi 001436687 035__ $$aSP(OCoLC)1251911217 001436687 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDX$$dOCLCO$$dEBLCP$$dOCLCF$$dN$T$$dOCLCQ$$dCOM$$dCASUM$$dOCLCQ 001436687 049__ $$aISEA 001436687 050_4 $$aRC280.B8 001436687 08204 $$a616.99/4490072$$223 001436687 24500 $$aTranslational research in breast cancer /$$cDong-Young Noh, Wonshik Han, Masakazu Toi, editors. 001436687 264_1 $$aSingapore :$$bSpringer,$$c[2021] 001436687 300__ $$a1 online resource (ix, 630 pages) :$$billustrations (some color) 001436687 336__ $$atext$$btxt$$2rdacontent 001436687 337__ $$acomputer$$bc$$2rdamedia 001436687 338__ $$aonline resource$$bcr$$2rdacarrier 001436687 4901_ $$aAdvances in Experimental Medicine and Biology,$$x0065-2598 ;$$vvolume 1187 001436687 5050_ $$aPart I. Introduction -- Chapter 1. Translational Research in Surgical Oncology: Introduction and My Own Experience as a Surgeon-Scientist -- Part II. Breast Cancer Biology and Cell Signaling Pathways -- Chapter 2. Phospholipase Signaling in Breast Cancer -- Chapter 3. HER2 Signaling in Breast Cancer -- Chapter 4. Ras Signaling in Breast Cancer -- Chapter 5. Epigenetic Regulation in Breast Cancer -- Chapter 6. Role of tRNAs in Breast Cancer Regulation -- Chapter 7. Fusion Genes in Breast Cancer -- Chapter 8. DNA Damage Repair Inhibitor for Breast Cancer Treatment -- Part III. Cancer Stem Cell and Tumor Heterogeneity in Breast Cancer -- Chapter 9. Breast Cancer Metastasis -- Chapter 10. Single Cell Genomics for Tumor Heterogeneity -- Chapter 11. Advances in Tumor Sampling and Sequencing in Breast Cancer and their Application in Precision Diagnostics and Therapeutics -- Chapter 12. Cancer Stem Cell in Immune Microenvironment -- Chapter 13. Theranostics for Breast Cancer Stem Cells -- Chapter 14. Patient-Derived Xenograft Models in Breast Cancer Research -- Part IV Biomarkers for Precision Medicine in Breast Cancer Patients -- Chapter 15. Proteomic Interrogation in Cancer Biomarker -- Chapter 16. Next-Generation Sequencing-Based Biomarkers in Breast Cancer -- Chapter 17. Liquid Biopsy in Breast Cancer: Circulating Tumor Cells and Circulating Tumor DNA -- Chapter 18. Current Biomarkers for Precision Medicine in Breast Cancer -- Chapter 19. The Potential Predictors in Chemotherapy Sensitivity -- Chapter 20. Hormone Resistance -- Part V. Managing High Risk Women -- Chapter 21. High-Risk Population Based on BC Risk Factors -- Chapter 22. Breast Cancer-Related Low Penetrance Genes -- Chapter 23. Rare Coding Variants Associated with Breast Cancer -- Chapter 24. Multigene Panel Testing for Hereditary Cancer and Genetic Counseling -- Chapter 25. BRCA and Breast Cancer-Related High-Penetrance Genes -- Part VI. Next Generation Clinical Research -- Chapter 26. Clinical Databases for Breast Cancer Research -- Chapter 27. Care for Breast Cancer Survivors -- Chapter 28. Considerations in Oncoplastic Surgery -- Chapter 29. Diet Before and After Breast Cancer -- Chapter 30. Current Trends in and Indications for Endoscopy-Assisted Breast Surgery for Breast Cancer -- Chapter 31. Minimal Invasive and Individualizing Management of the Axillary Nodes -- Chapter 32. Malignant Phyllodes of Breast -- Chapter 33. Next-Generation Clinical Trials and Research with Successful Collaborations -- Part VII. Epilogue -- Chapter 34. Transformation of the Patient and Society: A Patient Survivors' Group and Breast Cancer Awareness Campaign. 001436687 506__ $$aAccess limited to authorized users. 001436687 520__ $$aThis book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention is devoted to breast cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in breast cancer. Various patient-derived research models are discussed, and a further focus is the role of biomarkers in precision medicine for breast cancer patients. Next-generation clinical research receives detailed attention, addressing the increasingly important role of big data in breast cancer research and a wide range of other emerging developments. An entire section is also devoted to the management of women with high-risk breast cancer. Translational Research in Breast Cancer will help clinicians and scientists to optimize their collaboration in order to achieve the common goal of conquering breast cancer 001436687 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed May 20, 2021). 001436687 650_0 $$aBreast$$xCancer$$xResearch. 001436687 655_0 $$aElectronic books. 001436687 7001_ $$aNoh, Dong-Young,$$eeditor. 001436687 7001_ $$aHan, Wonshik,$$eeditor. 001436687 7001_ $$aToi, Masakazu,$$eeditor. 001436687 77608 $$iPrint version:$$z9813296194$$z9789813296190$$w(OCoLC)1108513181 001436687 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 1187.$$x0065-2598 001436687 852__ $$bebk 001436687 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-981-32-9620-6$$zOnline Access$$91397441.1 001436687 909CO $$ooai:library.usi.edu:1436687$$pGLOBAL_SET 001436687 980__ $$aBIB 001436687 980__ $$aEBOOK 001436687 982__ $$aEbook 001436687 983__ $$aOnline 001436687 994__ $$a92$$bISE