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001436789 0247_ $$a10.1007/978-3-030-62452-1$$2doi
001436789 035__ $$aSP(OCoLC)1252704575
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001436789 049__ $$aISEA
001436789 050_4 $$aR853.T58$$bT57 2021
001436789 08204 $$a610.72/4$$223
001436789 24500 $$aThree dimensional human organotypic models for biomedical research /$$cFabio Bagnoli, Rino Rappuoli, editors.
001436789 264_1 $$aCham :$$bSpringer,$$c[2021]
001436789 264_4 $$c©2021
001436789 300__ $$a1 online resource :$$billustrations (chiefly color)
001436789 336__ $$atext$$btxt$$2rdacontent
001436789 337__ $$acomputer$$bc$$2rdamedia
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001436789 347__ $$bPDF
001436789 4901_ $$aCurrent topics in microbiology and immunology,$$x0070-217X ;$$vvolume 430
001436789 504__ $$aIncludes bibliographical references.
001436789 5050_ $$aIntroduction: Rationale of using skin models in research -- Skin anatomy (human and animals for experimental research) -- In vivo skin models -- In vitro human skin models (Skin equivalents vs skin explants) -- Human skin models for studying cutaneous infections -- Skin animal models for pharmacological research -- Human skin models for pharmacological research -- Human skin models for allergological research -- Human skin models for cancer research -- Human skin models for vaccine research.
001436789 506__ $$aAccess limited to authorized users.
001436789 520__ $$aThis edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.
001436789 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed June 11, 2021).
001436789 650_0 $$aMedicine$$xResearch.
001436789 650_0 $$aTissue culture.
001436789 650_0 $$aBiological models.
001436789 650_6 $$aMédecine$$xRecherche.
001436789 650_6 $$aTissus (Histologie)$$xCulture.
001436789 650_6 $$aModèles biologiques.
001436789 655_0 $$aElectronic books.
001436789 7001_ $$aBagnoli, Fabio,$$eeditor.
001436789 7001_ $$aRappuoli, Rino,$$eeditor.
001436789 77608 $$iPrint version:$$tThree dimensional human organotypic models for biomedical research.$$dCham : Springer, [2021]$$z303062451X$$z9783030624514$$w(OCoLC)1197845117
001436789 830_0 $$aCurrent topics in microbiology and immunology ;$$v430.$$x0070-217X
001436789 852__ $$bebk
001436789 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-62452-1$$zOnline Access$$91397441.1
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