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Table of Contents
Intro
Preface to the 3rd edition
Acknowledgements
Contents
Contributors
Part I: Principles of DW Imaging
1: Basics of Diffusion Measurements by MRI
1.1 Diffusion: A Probabilistic Process
1.2 Diffusion Imaging in MR
1.3 Diffusion Imaging of the Brain
1.4 Principles of Magnetic Resonance Diffusion Imaging
1.5 Apparent Diffusion Coefficient
1.6 Diffusion Represents a Molecular Event
1.7 Requirements in Clinical Diffusion Imaging
1.8 Setting the b Value in Clinical DW Imaging
1.9 Future Trends in Clinical Diffusion Imaging
References
2: Diffusion-Weighted and Tensor Imaging of the Normal Brain
2.1 Introduction
2.2 Adult Brain
2.2.1 Low Signal in Basal Ganglia
2.2.2 Diffusion-Weighted Imaging of Gray and White Matter
2.2.3 Choroid Plexus
2.3 Pediatric Brain
2.3.1 Diffusion-Weighted Imaging and ADC of the Pediatric Brain
2.4 Diffusion Tensor Imaging and White Matter Anatomy
2.4.1 Association Fibers
2.4.2 Projection Fibers
2.4.3 Commissural Fibers
2.4.4 Fibers of the Brain Stem and Cerebellum
2.4.5 Clinical Importance of White Matter Fiber Anatomy
2.5 Conclusion
4.1 Preface
4.1.1 Theoretical Considerations for Diffusion Tensor and Diffusion Kurtosis Imaging
4.1.1.1 Diffusion-Weighted Imaging
4.1.1.2 Diffusion Tensor Imaging Based on a Gaussian Distribution
4.1.1.3 Non-Gaussian Diffusion and Diffusion Kurtosis Imaging
4.1.2 Studies Using Diffusion Kurtosis Imaging for Central Nervous System Diseases
4.1.2.1 Cerebrovascular Diseases
4.1.2.2 Brain Tumors
4.1.2.3 Demyelinating Diseases
4.1.2.4 Neurodegenerative Diseases
4.1.2.5 Development and Developmental Abnormalities
4.1.3 Glymphatic System and Diffusion Imaging
4.2 Conclusion
References
5: Intravoxel Incoherent Motion Imaging
5.1 Intravoxel Incoherent Motion Concept
5.2 IVIM Imaging
5.3 Methods of IVIM Analysis
5.4 Neuroimaging Applications of IVIM Imaging
5.4.1 Physiological Applications
5.4.2 IVIM Imaging of Brain Tumors
5.4.3 IVIM Imaging of Gliomas
5.4.4 Other Brain Tumors
5.4.5 Stroke and Brain Ischemia
5.4.6 Head and Neck Lesions
5.5 Pitfalls and Technical Limitations
References
6: Functional MRI and Diffusion Tensor Imaging
Preface to the 3rd edition
Acknowledgements
Contents
Contributors
Part I: Principles of DW Imaging
1: Basics of Diffusion Measurements by MRI
1.1 Diffusion: A Probabilistic Process
1.2 Diffusion Imaging in MR
1.3 Diffusion Imaging of the Brain
1.4 Principles of Magnetic Resonance Diffusion Imaging
1.5 Apparent Diffusion Coefficient
1.6 Diffusion Represents a Molecular Event
1.7 Requirements in Clinical Diffusion Imaging
1.8 Setting the b Value in Clinical DW Imaging
1.9 Future Trends in Clinical Diffusion Imaging
References
2: Diffusion-Weighted and Tensor Imaging of the Normal Brain
2.1 Introduction
2.2 Adult Brain
2.2.1 Low Signal in Basal Ganglia
2.2.2 Diffusion-Weighted Imaging of Gray and White Matter
2.2.3 Choroid Plexus
2.3 Pediatric Brain
2.3.1 Diffusion-Weighted Imaging and ADC of the Pediatric Brain
2.4 Diffusion Tensor Imaging and White Matter Anatomy
2.4.1 Association Fibers
2.4.2 Projection Fibers
2.4.3 Commissural Fibers
2.4.4 Fibers of the Brain Stem and Cerebellum
2.4.5 Clinical Importance of White Matter Fiber Anatomy
2.5 Conclusion
4.1 Preface
4.1.1 Theoretical Considerations for Diffusion Tensor and Diffusion Kurtosis Imaging
4.1.1.1 Diffusion-Weighted Imaging
4.1.1.2 Diffusion Tensor Imaging Based on a Gaussian Distribution
4.1.1.3 Non-Gaussian Diffusion and Diffusion Kurtosis Imaging
4.1.2 Studies Using Diffusion Kurtosis Imaging for Central Nervous System Diseases
4.1.2.1 Cerebrovascular Diseases
4.1.2.2 Brain Tumors
4.1.2.3 Demyelinating Diseases
4.1.2.4 Neurodegenerative Diseases
4.1.2.5 Development and Developmental Abnormalities
4.1.3 Glymphatic System and Diffusion Imaging
4.2 Conclusion
References
5: Intravoxel Incoherent Motion Imaging
5.1 Intravoxel Incoherent Motion Concept
5.2 IVIM Imaging
5.3 Methods of IVIM Analysis
5.4 Neuroimaging Applications of IVIM Imaging
5.4.1 Physiological Applications
5.4.2 IVIM Imaging of Brain Tumors
5.4.3 IVIM Imaging of Gliomas
5.4.4 Other Brain Tumors
5.4.5 Stroke and Brain Ischemia
5.4.6 Head and Neck Lesions
5.5 Pitfalls and Technical Limitations
References
6: Functional MRI and Diffusion Tensor Imaging