001437290 000__ 06304cam\a2200577\a\4500 001437290 001__ 1437290 001437290 003__ OCoLC 001437290 005__ 20230309004141.0 001437290 006__ m\\\\\o\\d\\\\\\\\ 001437290 007__ cr\un\nnnunnun 001437290 008__ 210612s2021\\\\sz\\\\\\o\\\\\001\0\eng\d 001437290 020__ $$a9783030646684$$q(electronic bk.) 001437290 020__ $$a3030646688$$q(electronic bk.) 001437290 020__ $$z9783030646677 001437290 0247_ $$a10.1007/978-3-030-64668-4$$2doi 001437290 035__ $$aSP(OCoLC)1256238433 001437290 040__ $$aEBLCP$$beng$$epn$$cEBLCP$$dGW5XE$$dOCLCO$$dEBLCP$$dOCLCF$$dUKAHL$$dOCLCQ$$dOCLCO$$dCOM$$dOCLCQ 001437290 049__ $$aISEA 001437290 050_4 $$aRC280.C6 001437290 08204 $$a616.99/434706$$223 001437290 24500 $$aColon cancer diagnosis and therapy.$$nVolume 2 /$$cNaveen Kumar Vishvakarma, Ganji Purnachandra Nagaraju, Dhananjay Shukla, editors. 001437290 260__ $$aCham :$$bSpringer,$$c2021. 001437290 300__ $$a1 online resource (459 pages) 001437290 336__ $$atext$$btxt$$2rdacontent 001437290 337__ $$acomputer$$bc$$2rdamedia 001437290 338__ $$aonline resource$$bcr$$2rdacarrier 001437290 500__ $$a6.1.2 Microflora. 001437290 500__ $$aIncludes index. 001437290 5050_ $$aIntro -- Preface -- Contents -- About the Editors -- Chapter 1: Application of Single Cell Technology in Colorectal Cancer -- 1.1 Introduction -- 1.2 Isolation Methods for Single Cells and Recent Developments in Single Cell Techniques -- 1.2.1 Single Cell Genome (DNA) Sequencing -- 1.2.2 Single Cell Transcriptome (RNA) Sequencing -- 1.2.3 Single Cell Epigenome Sequencing: DNA Methylation and Histone Sequencing -- 1.3 Applications -- 1.4 Conclusion -- References -- Chapter 2: Dietary Habits and Global Incidence of Colon Cancer -- 2.1 Introduction -- 2.2 The Difference in Dietary Habits 001437290 5058_ $$a2.2.1 The Western Diet -- 2.2.2 Mediterranean Diet (MeD) -- 2.2.3 African Diet -- 2.2.4 Asian Diet -- 2.2.4.1 Chinese Diet -- 2.2.4.2 Japanese Diet -- 2.3 Fruits and Vegetables (F & V) -- 2.3.1 Dietary Fiber -- 2.4 Grains -- 2.5 Meat -- 2.6 Carcinogens Produced by Cooking Methods -- 2.6.1 Barbecue (BBQ)/Grilling -- 2.6.2 Frying -- 2.6.3 Roasting -- 2.7 Carcinogen from Food Processing -- 2.8 Carcinogen from Food Preservation -- 2.8.1 Salt -- 2.8.2 Monosodium Glutamate (MSG) -- 2.9 Carcinogen from Pesticide Uses -- 2.10 Environment Pollutants -- 2.10.1 Aflatoxins (AFB1) -- 2.11 Carcinogen from Water 001437290 5058_ $$a2.12 Role of Lifestyle Factors -- 2.12.1 Obesity -- 2.12.2 Physical Inactivity -- 2.12.3 Alcohol Consumption -- 2.12.4 Smoking -- 2.13 Immune Status -- 2.14 Conclusion -- References -- Chapter 3: Diet and Colon Cancer: A Comprehensive Review -- 3.1 Introduction -- 3.2 Role of Nutrients in CRC -- 3.3 Calcium -- 3.4 Vitamin D -- 3.5 Dietary Fiber -- 3.6 Foods -- 3.7 Meat -- 3.8 Dairy Products -- 3.9 Fruits and Vegetables -- 3.10 Whole Grain -- 3.11 Dietary Pattern -- 3.12 Conclusion and Future Direction -- References -- Chapter 4: Recent Therapeutic Strategies for the Treatment of Colon Cancer 001437290 5058_ $$a4.1 Introduction -- 4.2 Molecular Aspects of Colon Cancer -- 4.3 Diagnostic and Therapeutic Targets of Colorectal Cancer -- 4.3.1 Treatment Approaches to Colon Cancer -- 4.3.1.1 Conventional Methods -- Surgery/Polypectomy -- Radiation Therapy -- Chemotherapy -- Targeted Therapy -- 4.3.1.2 Advanced Approaches to Treat Colon Cancer -- Immunotherapy -- Cancer Vaccines -- Cellular Therapies -- Gene Therapies -- Combination Therapies -- Nutritional Supplement Therapies -- References -- Chapter 5: Role of Bacteria in the Development of Cancer -- 5.1 Introduction 001437290 5058_ $$a5.2 Bacterial Factors Involved in Cancer Development -- 5.2.1 Cell Surface Components -- 5.2.2 Bacterial Toxins -- 5.2.3 Bacterial Effector Proteins -- 5.2.4 Other Factors -- 5.3 Bacterial Species Involved in Colon Cancer Development -- 5.3.1 Escherichia coli -- 5.3.2 Salmonella enterica -- 5.3.3 Fusobacterium nucleatum -- 5.3.4 Bacteroides fragilis -- 5.3.5 Streptococcus gallolyticus -- 5.3.6 Enterococcus faecalis -- 5.4 Conclusions -- References -- Chapter 6: Role of Bacterial Infection (H. pylori) in Colon Carcinogenesis and Therapeutic Approaches -- 6.1 Introduction -- 6.1.1 Colorectal Polyp 001437290 506__ $$aAccess limited to authorized users. 001437290 520__ $$aColorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide. Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early stage diagnosis. This book is the second of three volumes on recent developments in colorectal diagnosis and therapy. Each volume can be read on its own, or together. Each volume focuses on different novel therapeutic advances, biomarkers, and identifies therapeutic targets for treatment. Written by leading international experts in the field, coverage addresses the role of diet habits and lifestyle in reducing gastrointestinal disorders and incidence of CRC. Chapters discuss current and future diagnostic and therapeutic options for colorectal cancer patients, focusing on immunotherapeutics, nanomedicine, biomarkers, and dietary factors for the effective management of colon cancer. 001437290 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed June 21, 2021). 001437290 650_0 $$aColon (Anatomy)$$xCancer$$xDiagnosis. 001437290 650_0 $$aColon (Anatomy)$$xCancer$$xTreatment. 001437290 650_0 $$aRectum$$xCancer$$xTreatment. 001437290 650_0 $$aRectum$$xCancer$$xDiagnosis. 001437290 655_0 $$aElectronic books. 001437290 7001_ $$aVishvakarma, Naveen Kumar. 001437290 7001_ $$aNagaraju, Ganji Purnachandra. 001437290 7001_ $$aShukla, Dhananjay. 001437290 77608 $$iPrint version:$$aVishvakarma, Naveen Kumar.$$tColon Cancer Diagnosis and Therapy.$$dCham : Springer International Publishing AG, ©2021$$z9783030646677 001437290 852__ $$bebk 001437290 85640 $$3Springer Nature$$uhttps://univsouthin.idm.oclc.org/login?url=https://link.springer.com/10.1007/978-3-030-64668-4$$zOnline Access$$91397441.1 001437290 909CO $$ooai:library.usi.edu:1437290$$pGLOBAL_SET 001437290 980__ $$aBIB 001437290 980__ $$aEBOOK 001437290 982__ $$aEbook 001437290 983__ $$aOnline 001437290 994__ $$a92$$bISE